Motif ID: Maff

Z-value: 0.507


Transcription factors associated with Maff:

Gene SymbolEntrez IDGene Name
Maff ENSMUSG00000042622.7 Maff

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Maffmm10_v2_chr15_+_79347534_793475560.411.3e-03Click!


Activity profile for motif Maff.

activity profile for motif Maff


Sorted Z-values histogram for motif Maff

Sorted Z-values for motif Maff



Network of associatons between targets according to the STRING database.



First level regulatory network of Maff

PNG image of the network

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Top targets:


Showing 1 to 20 of 73 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_3270767 5.138 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr4_-_136886187 3.989 ENSMUST00000046384.8
 C1qb
complement component 1, q subcomponent, beta polypeptide
chr14_+_118787894 3.903 ENSMUST00000047761.6
ENSMUST00000071546.7
 Cldn10

claudin 10

chr7_-_110862944 3.332 ENSMUST00000033050.3
 Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr13_-_23710714 3.044 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
 Hfe


hemochromatosis


chr6_+_120773633 2.700 ENSMUST00000112682.2
 Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr17_-_25570678 2.597 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr16_-_22439719 2.216 ENSMUST00000079601.6
 Etv5
ets variant gene 5
chr5_+_104435112 2.132 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
 Spp1





secreted phosphoprotein 1





chr1_-_120074023 1.615 ENSMUST00000056089.7
 Tmem37
transmembrane protein 37
chr11_+_82101836 1.493 ENSMUST00000000194.3
 Ccl12
chemokine (C-C motif) ligand 12
chr4_+_102421518 1.484 ENSMUST00000106904.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr19_+_56722372 1.425 ENSMUST00000038949.4
 Adrb1
adrenergic receptor, beta 1
chr3_-_59262825 1.149 ENSMUST00000050360.7
 P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr5_+_140505550 1.098 ENSMUST00000043050.8
ENSMUST00000124142.1
 Chst12

carbohydrate sulfotransferase 12

chr12_+_35047180 1.068 ENSMUST00000048519.9
ENSMUST00000163677.1
 Snx13

sorting nexin 13

chr7_+_84528964 1.043 ENSMUST00000180387.1
 Gm2115
predicted gene 2115
chr11_-_109473598 1.042 ENSMUST00000070152.5
 Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr18_+_4921662 0.938 ENSMUST00000143254.1
 Svil
supervillin
chr7_-_100964371 0.929 ENSMUST00000060174.4
 P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 5.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 4.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 3.3 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
1.0 3.0 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.9 2.6 GO:0072034 renal vesicle induction(GO:0072034)
0.4 2.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 2.1 GO:0033280 response to vitamin D(GO:0033280)
0.2 1.6 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.5 1.5 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 1.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.5 1.4 GO:1900133 renin secretion into blood stream(GO:0002001) negative regulation of urine volume(GO:0035811) regulation of renin secretion into blood stream(GO:1900133)
0.4 1.1 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.4 1.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.0 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.3 0.9 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 0.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.9 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.7 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.2 0.6 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:0045177 apical part of cell(GO:0045177)
0.1 4.0 GO:0005581 collagen trimer(GO:0005581)
0.0 3.9 GO:0005923 bicellular tight junction(GO:0005923)
0.6 3.0 GO:1990357 terminal web(GO:1990357)
0.0 2.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.9 GO:0005770 late endosome(GO:0005770)
0.0 1.8 GO:0005769 early endosome(GO:0005769)
0.1 1.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.3 GO:0043034 costamere(GO:0043034)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.7 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.1 GO:0008430 selenium binding(GO:0008430)
0.2 3.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 3.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3 3.0 GO:0039706 co-receptor binding(GO:0039706)
0.0 2.7 GO:0015293 symporter activity(GO:0015293)
0.3 2.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 2.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.6 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
0.0 1.6 GO:0005262 calcium channel activity(GO:0005262)
0.4 1.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 1.5 GO:0030552 cAMP binding(GO:0030552)
0.5 1.4 GO:0051379 epinephrine binding(GO:0051379)
0.3 1.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 1.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.9 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0070402 NADPH binding(GO:0070402)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)