Motif ID: Maz_Zfp281

Z-value: 1.366

Transcription factors associated with Maz_Zfp281:

Gene SymbolEntrez IDGene Name
Maz ENSMUSG00000030678.6 Maz
Zfp281 ENSMUSG00000041483.8 Zfp281

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp281mm10_v2_chr1_+_136624901_1366249490.229.0e-02Click!
Mazmm10_v2_chr7_-_127026479_127026496-0.057.0e-01Click!


Activity profile for motif Maz_Zfp281.

activity profile for motif Maz_Zfp281


Sorted Z-values histogram for motif Maz_Zfp281

Sorted Z-values for motif Maz_Zfp281



Network of associatons between targets according to the STRING database.



First level regulatory network of Maz_Zfp281

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_144939823 15.424 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr10_-_120476469 12.746 ENSMUST00000072777.7
ENSMUST00000159699.1
 Hmga2

high mobility group AT-hook 2

chr14_-_98169542 10.669 ENSMUST00000069334.7
ENSMUST00000071533.6
 Dach1

dachshund 1 (Drosophila)

chrX_-_106485367 10.667 ENSMUST00000140707.1
 Fndc3c1
fibronectin type III domain containing 3C1
chr14_-_52316323 10.198 ENSMUST00000135523.1
 Sall2
sal-like 2 (Drosophila)
chrX_-_106485214 9.934 ENSMUST00000039447.7
 Fndc3c1
fibronectin type III domain containing 3C1
chr16_+_84774123 9.409 ENSMUST00000114195.1
 Jam2
junction adhesion molecule 2
chr8_-_87959560 8.703 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr10_-_127341583 8.670 ENSMUST00000026474.3
 Gli1
GLI-Kruppel family member GLI1
chr3_+_131110350 8.341 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
 Lef1


lymphoid enhancer binding factor 1


chr1_-_138847579 7.857 ENSMUST00000093486.3
ENSMUST00000046870.6
 Lhx9

LIM homeobox protein 9

chr11_+_88718442 7.812 ENSMUST00000138007.1
 C030037D09Rik
RIKEN cDNA C030037D09 gene
chr11_-_88718165 7.770 ENSMUST00000107908.1
 Msi2
musashi RNA-binding protein 2
chr7_+_19094594 7.501 ENSMUST00000049454.5
 Six5
sine oculis-related homeobox 5
chr11_-_88718223 7.456 ENSMUST00000107909.1
 Msi2
musashi RNA-binding protein 2
chr17_+_85620816 7.217 ENSMUST00000175898.2
 Six3
sine oculis-related homeobox 3
chr6_-_72390659 7.129 ENSMUST00000059983.9
 Vamp8
vesicle-associated membrane protein 8
chr7_-_144738520 7.115 ENSMUST00000118556.2
ENSMUST00000033393.8
 Ano1

anoctamin 1, calcium activated chloride channel

chr3_+_87948666 6.995 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr13_-_29984219 6.994 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,224 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 28.3 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.2 23.7 GO:0051028 mRNA transport(GO:0051028)
1.3 21.3 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
2.0 18.0 GO:0010587 miRNA catabolic process(GO:0010587)
2.0 17.6 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
1.8 17.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 17.4 GO:0008380 RNA splicing(GO:0008380)
3.4 17.2 GO:0035262 gonad morphogenesis(GO:0035262)
5.4 16.2 GO:0097402 neuroblast migration(GO:0097402)
1.8 16.2 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.7 15.6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
1.7 15.0 GO:0097421 liver regeneration(GO:0097421)
0.9 15.0 GO:0050434 positive regulation of viral transcription(GO:0050434)
1.7 14.9 GO:0060613 fat pad development(GO:0060613)
0.5 14.9 GO:0006270 DNA replication initiation(GO:0006270)
2.7 13.6 GO:0015705 iodide transport(GO:0015705)
0.3 13.6 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.7 13.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.3 13.0 GO:0043297 apical junction assembly(GO:0043297)
1.0 12.7 GO:0001779 natural killer cell differentiation(GO:0001779)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 376 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 117.9 GO:0005634 nucleus(GO:0005634)
0.1 99.0 GO:0005654 nucleoplasm(GO:0005654)
0.2 60.5 GO:0005667 transcription factor complex(GO:0005667)
0.9 39.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.6 34.2 GO:0005844 polysome(GO:0005844)
0.1 33.0 GO:0031012 extracellular matrix(GO:0031012)
0.2 30.0 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 26.7 GO:0005694 chromosome(GO:0005694)
0.4 24.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 23.0 GO:0005681 spliceosomal complex(GO:0005681)
0.2 22.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
1.9 20.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.4 17.8 GO:0005876 spindle microtubule(GO:0005876)
0.2 13.8 GO:0005643 nuclear pore(GO:0005643)
1.1 12.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.6 12.4 GO:0001741 XY body(GO:0001741)
0.7 12.2 GO:0097470 ribbon synapse(GO:0097470)
0.6 11.8 GO:0016580 Sin3 complex(GO:0016580)
0.9 11.4 GO:0097542 ciliary tip(GO:0097542)
1.0 11.2 GO:0005915 zonula adherens(GO:0005915)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 646 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 94.7 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.6 49.2 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 32.6 GO:0003677 DNA binding(GO:0003677)
1.2 28.0 GO:0070064 proline-rich region binding(GO:0070064)
1.0 21.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 21.8 GO:0001047 core promoter binding(GO:0001047)
1.0 21.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 20.6 GO:0033613 activating transcription factor binding(GO:0033613)
1.8 20.2 GO:0003680 AT DNA binding(GO:0003680)
0.7 19.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
2.2 17.7 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.7 17.6 GO:0071837 HMG box domain binding(GO:0071837)
0.9 17.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
1.0 16.2 GO:0070410 co-SMAD binding(GO:0070410)
1.0 15.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.4 15.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.4 15.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.3 15.0 GO:0051287 NAD binding(GO:0051287)
0.5 14.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 14.3 GO:0042393 histone binding(GO:0042393)