Motif ID: Mef2b

Z-value: 1.055


Transcription factors associated with Mef2b:

Gene SymbolEntrez IDGene Name
Mef2b ENSMUSG00000079033.3 Mef2b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mef2bmm10_v2_chr8_+_70152754_701527810.133.3e-01Click!


Activity profile for motif Mef2b.

activity profile for motif Mef2b


Sorted Z-values histogram for motif Mef2b

Sorted Z-values for motif Mef2b



Network of associatons between targets according to the STRING database.



First level regulatory network of Mef2b

PNG image of the network

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Top targets:


Showing 1 to 20 of 193 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103843154 23.071 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr6_-_23248264 14.668 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr7_-_142899985 13.016 ENSMUST00000000219.3
 Th
tyrosine hydroxylase
chr7_-_144738478 11.411 ENSMUST00000121758.1
 Ano1
anoctamin 1, calcium activated chloride channel
chr2_-_94264713 7.091 ENSMUST00000129661.1
 E530001K10Rik
RIKEN cDNA E530001K10 gene
chr2_-_94264745 6.858 ENSMUST00000134563.1
 E530001K10Rik
RIKEN cDNA E530001K10 gene
chr7_-_144738520 6.590 ENSMUST00000118556.2
ENSMUST00000033393.8
 Ano1

anoctamin 1, calcium activated chloride channel

chr17_-_58991343 5.653 ENSMUST00000025064.7
 2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr5_-_116422858 5.156 ENSMUST00000036991.4
 Hspb8
heat shock protein 8
chr3_-_98814434 4.838 ENSMUST00000029463.6
 Hsd3b6
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
chr4_+_119108711 4.695 ENSMUST00000030398.3
 Slc2a1
solute carrier family 2 (facilitated glucose transporter), member 1
chr4_+_119108795 4.451 ENSMUST00000134105.1
ENSMUST00000144329.1
 Slc2a1

solute carrier family 2 (facilitated glucose transporter), member 1

chr18_+_50030977 4.363 ENSMUST00000145726.1
ENSMUST00000128377.1
 Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chrX_+_75096039 4.162 ENSMUST00000131155.1
ENSMUST00000132000.1
 Dkc1

dyskeratosis congenita 1, dyskerin

chr2_+_120463566 4.070 ENSMUST00000028749.7
ENSMUST00000110721.1
 Capn3

calpain 3

chr6_-_126939524 3.913 ENSMUST00000144954.1
ENSMUST00000112221.1
ENSMUST00000112220.1
 Rad51ap1


RAD51 associated protein 1


chr3_+_40800013 3.826 ENSMUST00000026858.5
ENSMUST00000170825.1
 Plk4

polo-like kinase 4

chrX_-_93832106 3.825 ENSMUST00000045748.6
 Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
chrX_+_75095854 3.753 ENSMUST00000033776.8
 Dkc1
dyskeratosis congenita 1, dyskerin
chr17_+_91236787 3.749 ENSMUST00000057074.8
 Gm6741
predicted gene 6741

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.6 23.1 GO:0015671 oxygen transport(GO:0015671)
3.6 18.0 GO:0015705 iodide transport(GO:0015705)
2.4 14.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
3.3 13.0 GO:0042414 epinephrine metabolic process(GO:0042414)
3.0 9.1 GO:0042908 xenobiotic transport(GO:0042908)
2.6 7.9 GO:1990481 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) snRNA pseudouridine synthesis(GO:0031120) mRNA pseudouridine synthesis(GO:1990481)
0.3 6.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 6.2 GO:0042384 cilium assembly(GO:0042384)
0.4 6.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 4.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 4.8 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 4.5 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.1 4.4 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
1.4 4.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.2 4.0 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.4 3.9 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 3.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
1.0 3.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.8 3.8 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.3 3.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 23.2 GO:0034707 chloride channel complex(GO:0034707)
2.9 23.1 GO:0005833 hemoglobin complex(GO:0005833)
0.5 13.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
1.0 10.4 GO:0001939 female pronucleus(GO:0001939)
2.0 7.9 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 6.2 GO:0005814 centriole(GO:0005814)
0.5 3.8 GO:0098536 deuterosome(GO:0098536)
0.7 3.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 3.6 GO:0030118 clathrin coat(GO:0030118)
0.0 3.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.7 3.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 3.3 GO:0031528 microvillus membrane(GO:0031528)
0.1 3.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.5 3.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 3.0 GO:0000922 spindle pole(GO:0000922)
0.0 3.0 GO:0016607 nuclear speck(GO:0016607)
0.3 2.8 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 2.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 2.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 2.6 GO:0008023 transcription elongation factor complex(GO:0008023)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.8 23.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
4.5 18.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
2.2 13.0 GO:0035240 dopamine binding(GO:0035240)
2.9 11.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 11.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
2.0 7.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.4 6.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.3 6.1 GO:0070402 NADPH binding(GO:0070402)
0.1 5.3 GO:0000049 tRNA binding(GO:0000049)
0.0 4.9 GO:0017137 Rab GTPase binding(GO:0017137)
1.6 4.8 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.5 4.1 GO:0031432 titin binding(GO:0031432)
0.1 4.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 3.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 3.9 GO:0003697 single-stranded DNA binding(GO:0003697)
1.0 3.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 3.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 3.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.7 3.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 3.3 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)