Motif ID: Meis2

Z-value: 1.332


Transcription factors associated with Meis2:

Gene SymbolEntrez IDGene Name
Meis2 ENSMUSG00000027210.14 Meis2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meis2mm10_v2_chr2_-_116065798_1160658530.683.3e-09Click!


Activity profile for motif Meis2.

activity profile for motif Meis2


Sorted Z-values histogram for motif Meis2

Sorted Z-values for motif Meis2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meis2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_194619815 14.215 ENSMUST00000027952.5
 Plxna2
plexin A2
chr6_+_49822710 11.556 ENSMUST00000031843.6
 Npy
neuropeptide Y
chr7_+_44850393 10.276 ENSMUST00000136232.1
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr5_-_100159261 9.235 ENSMUST00000139520.1
 Tmem150c
transmembrane protein 150C
chr9_-_121495678 9.172 ENSMUST00000035120.4
 Cck
cholecystokinin
chr5_-_109558957 8.920 ENSMUST00000044579.7
 Crlf2
cytokine receptor-like factor 2
chr19_+_42247544 8.904 ENSMUST00000122375.1
 Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr4_+_128058962 8.765 ENSMUST00000184063.1
 Csmd2
CUB and Sushi multiple domains 2
chr3_-_82074639 8.458 ENSMUST00000029635.8
 Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr7_+_48959089 7.575 ENSMUST00000183659.1
 Nav2
neuron navigator 2
chr8_+_120114144 7.531 ENSMUST00000108948.1
ENSMUST00000034281.6
ENSMUST00000108951.1
 6430548M08Rik


RIKEN cDNA 6430548M08 gene


chr11_+_78324200 7.459 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr18_+_36939178 7.391 ENSMUST00000115662.2
 Pcdha2
protocadherin alpha 2
chr17_+_8924109 7.342 ENSMUST00000149440.1
 Pde10a
phosphodiesterase 10A
chr3_-_107518001 7.092 ENSMUST00000169449.1
ENSMUST00000029499.8
 Slc6a17

solute carrier family 6 (neurotransmitter transporter), member 17

chr9_-_86880414 7.009 ENSMUST00000074501.5
ENSMUST00000098495.3
ENSMUST00000074468.6
ENSMUST00000036347.6
 Snap91



synaptosomal-associated protein 91



chr1_+_156558759 6.482 ENSMUST00000173929.1
 Abl2
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr12_-_24493656 6.434 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr4_+_42922253 6.315 ENSMUST00000139100.1
 N28178
expressed sequence N28178
chr15_-_100599864 6.270 ENSMUST00000177247.2
ENSMUST00000177505.2
 Pou6f1

POU domain, class 6, transcription factor 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 143 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 14.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.3 12.5 GO:0006376 mRNA splice site selection(GO:0006376)
2.3 11.6 GO:0019732 antifungal humoral response(GO:0019732)
0.6 10.3 GO:0045792 negative regulation of cell size(GO:0045792)
2.5 10.1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.1 9.6 GO:0030032 lamellipodium assembly(GO:0030032)
1.5 8.9 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.4 8.5 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.8 8.4 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
2.7 8.1 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.4 8.1 GO:0048268 clathrin coat assembly(GO:0048268)
1.3 7.7 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 7.7 GO:0007020 microtubule nucleation(GO:0007020)
0.1 7.7 GO:0008643 carbohydrate transport(GO:0008643)
1.9 7.6 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.7 7.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4 7.3 GO:0046069 cGMP catabolic process(GO:0046069)
1.4 7.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.9 6.9 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 6.3 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 15.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 15.2 GO:0043195 terminal bouton(GO:0043195)
1.3 14.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 12.9 GO:0008021 synaptic vesicle(GO:0008021)
1.1 10.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.9 10.3 GO:0031931 TORC1 complex(GO:0031931)
0.1 9.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 9.6 GO:0097060 synaptic membrane(GO:0097060)
1.9 9.4 GO:0044316 cone cell pedicle(GO:0044316)
0.7 9.2 GO:0043203 axon hillock(GO:0043203)
1.6 8.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 7.3 GO:0043198 dendritic shaft(GO:0043198)
0.6 7.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 7.0 GO:0000139 Golgi membrane(GO:0000139)
0.3 6.9 GO:0001891 phagocytic cup(GO:0001891)
0.4 6.5 GO:0005614 interstitial matrix(GO:0005614)
0.5 5.7 GO:0061700 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.4 5.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.2 4.8 GO:0045098 type III intermediate filament(GO:0045098)
0.3 4.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 108 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 18.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
1.0 14.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 13.4 GO:0003779 actin binding(GO:0003779)
1.1 10.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.6 10.1 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 9.9 GO:0005125 cytokine activity(GO:0005125)
1.6 8.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
1.9 7.7 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
1.2 7.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.4 7.3 GO:0030553 cGMP binding(GO:0030553)
0.4 7.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.8 7.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 7.0 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 6.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 6.6 GO:0008201 heparin binding(GO:0008201)
0.3 6.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 6.2 GO:0030552 cAMP binding(GO:0030552)
0.1 5.7 GO:0017022 myosin binding(GO:0017022)
1.4 5.4 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.4 5.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)