Motif ID: Meox2

Z-value: 0.777


Transcription factors associated with Meox2:

Gene SymbolEntrez IDGene Name
Meox2 ENSMUSG00000036144.5 Meox2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meox2mm10_v2_chr12_+_37108533_371085460.211.1e-01Click!


Activity profile for motif Meox2.

activity profile for motif Meox2


Sorted Z-values histogram for motif Meox2

Sorted Z-values for motif Meox2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meox2

PNG image of the network

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Top targets:


Showing 1 to 20 of 145 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_26119811 8.697 ENSMUST00000173617.1
 Duxbl2
doubl homeobox B-like 2
chr14_+_25980039 8.462 ENSMUST00000173155.1
 Duxbl1
double homeobox B-like 1
chr14_+_26259109 6.927 ENSMUST00000174494.1
 Duxbl3
double homeobox B-like 3
chr8_-_46294592 5.957 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr14_+_25979401 3.760 ENSMUST00000173580.1
 Duxbl1
double homeobox B-like 1
chr14_+_26119173 3.133 ENSMUST00000174564.1
 Duxbl2
doubl homeobox B-like 2
chr14_+_26258786 3.133 ENSMUST00000172517.1
 Duxbl3
double homeobox B-like 3
chr5_-_62766153 2.726 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_33923582 2.723 ENSMUST00000168727.1
 Gdf10
growth differentiation factor 10
chr13_+_104229366 2.564 ENSMUST00000022227.6
 Cenpk
centromere protein K
chr11_-_83645621 2.079 ENSMUST00000182502.1
 Rpl9-ps1
ribosomal protein L9, pseudogene 1
chr16_+_42907563 1.865 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr16_+_14906622 1.852 ENSMUST00000090277.1
 Efcab1
EF hand calcium binding domain 1
chr17_+_86963077 1.839 ENSMUST00000024956.8
 Rhoq
ras homolog gene family, member Q
chr15_+_85116829 1.815 ENSMUST00000105085.1
 Gm10923
predicted gene 10923
chr3_-_98339921 1.798 ENSMUST00000065793.5
 Phgdh
3-phosphoglycerate dehydrogenase
chr9_-_36726374 1.725 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
 Chek1


checkpoint kinase 1


chr3_+_127553462 1.706 ENSMUST00000043108.4
 4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr8_+_12395287 1.651 ENSMUST00000180353.1
 Sox1
SRY-box containing gene 1
chr3_+_107291215 1.641 ENSMUST00000029502.7
 Slc16a4
solute carrier family 16 (monocarboxylic acid transporters), member 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 13.0 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.3 6.0 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.1 2.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 1.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.6 1.8 GO:0006566 threonine metabolic process(GO:0006566)
0.1 1.8 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.3 1.7 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 1.7 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.5 1.6 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 1.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 1.6 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.5 1.5 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2 1.5 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.4 1.3 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.3 1.3 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 1.3 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 1.3 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.2 1.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 1.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.6 GO:0000776 kinetochore(GO:0000776)
0.0 1.8 GO:0005884 actin filament(GO:0005884)
0.3 1.5 GO:0097149 centralspindlin complex(GO:0097149)
0.0 1.5 GO:0005657 replication fork(GO:0005657)
0.1 1.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.2 GO:0000922 spindle pole(GO:0000922)
0.2 1.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 0.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 0.8 GO:0008623 CHRAC(GO:0008623)
0.2 0.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.8 GO:0005844 polysome(GO:0005844)
0.0 0.8 GO:0005776 autophagosome(GO:0005776)
0.2 0.6 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 0.5 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0045275 respiratory chain complex III(GO:0045275)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 4.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 2.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.8 GO:0051287 NAD binding(GO:0051287)
0.6 1.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 1.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 1.5 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.3 GO:0016836 hydro-lyase activity(GO:0016836)
0.2 1.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 1.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 1.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.0 GO:0005507 copper ion binding(GO:0005507)
0.2 0.8 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.8 GO:0043022 ribosome binding(GO:0043022)
0.1 0.6 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)