Motif ID: Mnx1_Lhx6_Lmx1a
Z-value: 0.783
Transcription factors associated with Mnx1_Lhx6_Lmx1a:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Lhx6 | ENSMUSG00000026890.13 | Lhx6 |
| Lmx1a | ENSMUSG00000026686.8 | Lmx1a |
| Mnx1 | ENSMUSG00000001566.8 | Mnx1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Lhx6 | mm10_v2_chr2_-_36104060_36104073 | -0.42 | 8.8e-04 | Click! |
| Lmx1a | mm10_v2_chr1_+_167689552_167689563 | 0.27 | 3.5e-02 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 118 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 7.2 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.9 | 7.0 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 2.1 | 6.2 | GO:0060489 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
| 0.9 | 5.1 | GO:0060648 | mammary gland bud morphogenesis(GO:0060648) |
| 0.0 | 4.9 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.1 | 4.8 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.2 | 4.3 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 1.1 | 4.2 | GO:0021847 | ventricular zone neuroblast division(GO:0021847) |
| 0.2 | 4.0 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 1.1 | 3.3 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
| 0.1 | 3.3 | GO:0051693 | actin filament capping(GO:0051693) |
| 0.7 | 2.9 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
| 0.6 | 2.8 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.1 | 2.6 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.0 | 2.6 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
| 0.2 | 2.4 | GO:0080111 | DNA demethylation(GO:0080111) |
| 0.2 | 2.3 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.3 | 2.2 | GO:0007195 | adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) |
| 0.0 | 2.2 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 2.1 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 48 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 7.2 | GO:0002102 | podosome(GO:0002102) |
| 1.6 | 6.2 | GO:0060187 | cell pole(GO:0060187) |
| 0.1 | 5.7 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.2 | 4.2 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 4.2 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.0 | 2.6 | GO:0043296 | apical junction complex(GO:0043296) |
| 0.4 | 2.4 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.4 | 2.2 | GO:0031523 | Myb complex(GO:0031523) |
| 0.0 | 2.2 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.4 | 2.1 | GO:0008623 | CHRAC(GO:0008623) |
| 0.0 | 2.1 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.1 | 1.8 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.0 | 1.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.0 | 1.5 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.1 | 1.4 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 1.2 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 1.2 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 1.1 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.1 | 0.8 | GO:0098536 | deuterosome(GO:0098536) |
| 0.0 | 0.8 | GO:0000788 | nuclear nucleosome(GO:0000788) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 85 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.0 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 7.4 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
| 1.0 | 7.3 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.3 | 5.1 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.0 | 5.1 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.3 | 4.2 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
| 0.1 | 4.1 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 3.9 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 3.5 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.1 | 3.3 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.2 | 2.8 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 2.8 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.2 | 2.6 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.1 | 2.4 | GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) |
| 0.1 | 2.4 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 2.3 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.6 | 2.2 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.2 | 1.9 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.1 | 1.9 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.4 | 1.8 | GO:0008142 | oxysterol binding(GO:0008142) |
|
|
|