Motif ID: Mnx1_Lhx6_Lmx1a
Z-value: 0.783
Transcription factors associated with Mnx1_Lhx6_Lmx1a:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Lhx6 | ENSMUSG00000026890.13 | Lhx6 |
| Lmx1a | ENSMUSG00000026686.8 | Lmx1a |
| Mnx1 | ENSMUSG00000001566.8 | Mnx1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Lhx6 | mm10_v2_chr2_-_36104060_36104073 | -0.42 | 8.8e-04 | Click! |
| Lmx1a | mm10_v2_chr1_+_167689552_167689563 | 0.27 | 3.5e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 6.2 | GO:0060489 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
| 1.1 | 3.3 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
| 1.1 | 4.2 | GO:0021847 | ventricular zone neuroblast division(GO:0021847) |
| 0.9 | 7.0 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.9 | 5.1 | GO:0060648 | mammary gland bud morphogenesis(GO:0060648) |
| 0.7 | 2.9 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
| 0.6 | 2.8 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.5 | 1.5 | GO:2000852 | regulation of corticosterone secretion(GO:2000852) |
| 0.5 | 7.2 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.5 | 1.4 | GO:0060523 | prostate epithelial cord elongation(GO:0060523) |
| 0.4 | 1.2 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) |
| 0.4 | 1.2 | GO:0048818 | embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364) |
| 0.4 | 1.4 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 0.3 | 1.0 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.3 | 1.3 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.3 | 0.9 | GO:1905065 | cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) positive regulation of vascular smooth muscle cell differentiation(GO:1905065) |
| 0.3 | 0.8 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 0.3 | 2.2 | GO:0007195 | adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) |
| 0.3 | 1.1 | GO:0035553 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
| 0.3 | 1.8 | GO:0072539 | T-helper 17 cell differentiation(GO:0072539) |
| 0.2 | 4.0 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.2 | 4.3 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.2 | 2.3 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.2 | 1.2 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.2 | 0.8 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.2 | 1.9 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.2 | 0.5 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.2 | 0.5 | GO:0072356 | chromosome passenger complex localization to kinetochore(GO:0072356) |
| 0.2 | 2.4 | GO:0080111 | DNA demethylation(GO:0080111) |
| 0.2 | 0.7 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.2 | 0.8 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
| 0.2 | 0.7 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) resolution of recombination intermediates(GO:0071139) |
| 0.2 | 1.6 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 0.2 | 0.5 | GO:0051798 | positive regulation of hair follicle development(GO:0051798) |
| 0.2 | 1.6 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.2 | 0.6 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
| 0.1 | 0.4 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.1 | 1.8 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.1 | 4.8 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.1 | 0.4 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
| 0.1 | 1.6 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.1 | 0.9 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.1 | 1.7 | GO:0030497 | fatty acid elongation(GO:0030497) |
| 0.1 | 0.4 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) |
| 0.1 | 0.2 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 0.1 | 0.9 | GO:1902916 | positive regulation of protein polyubiquitination(GO:1902916) |
| 0.1 | 2.6 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.1 | 1.9 | GO:0007530 | sex determination(GO:0007530) |
| 0.1 | 0.4 | GO:0071449 | cellular response to lipid hydroperoxide(GO:0071449) |
| 0.1 | 1.1 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 0.1 | 0.7 | GO:1900194 | negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194) |
| 0.1 | 0.1 | GO:0072106 | regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) |
| 0.1 | 0.3 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 0.1 | 0.8 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.1 | 0.8 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 0.1 | 1.6 | GO:0033194 | response to hydroperoxide(GO:0033194) |
| 0.1 | 0.7 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
| 0.1 | 0.4 | GO:0030242 | pexophagy(GO:0030242) |
| 0.1 | 0.4 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
| 0.1 | 3.3 | GO:0051693 | actin filament capping(GO:0051693) |
| 0.1 | 0.6 | GO:0046689 | response to mercury ion(GO:0046689) |
| 0.1 | 1.2 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 0.2 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
| 0.1 | 1.7 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.1 | 0.4 | GO:0051461 | corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
| 0.1 | 0.1 | GO:0060527 | prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527) |
| 0.1 | 1.5 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.1 | 0.2 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
| 0.1 | 0.4 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.1 | 1.1 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
| 0.1 | 0.4 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 0.1 | 0.3 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
| 0.0 | 0.3 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 0.0 | 0.5 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.0 | 0.7 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.6 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.5 | GO:0009396 | folic acid-containing compound biosynthetic process(GO:0009396) |
| 0.0 | 0.7 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
| 0.0 | 0.2 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.0 | 0.3 | GO:0036233 | glycine import(GO:0036233) |
| 0.0 | 1.5 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 0.8 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
| 0.0 | 0.2 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.0 | 1.1 | GO:0071384 | cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385) |
| 0.0 | 0.3 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.0 | 0.6 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 0.0 | 0.2 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.0 | 0.9 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.0 | 0.3 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.0 | 1.0 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
| 0.0 | 0.2 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.0 | 2.2 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 0.8 | GO:0007588 | excretion(GO:0007588) |
| 0.0 | 0.8 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 4.9 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 2.6 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
| 0.0 | 0.4 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.7 | GO:0034508 | centromere complex assembly(GO:0034508) |
| 0.0 | 0.1 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
| 0.0 | 0.2 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
| 0.0 | 0.0 | GO:0090324 | negative regulation of oxidative phosphorylation(GO:0090324) |
| 0.0 | 1.8 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.0 | 1.0 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.0 | 0.5 | GO:0006303 | double-strand break repair via nonhomologous end joining(GO:0006303) |
| 0.0 | 2.1 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
| 0.0 | 0.3 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.0 | 0.5 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.0 | 0.6 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.4 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.4 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.0 | 0.0 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.0 | 0.8 | GO:0071774 | response to fibroblast growth factor(GO:0071774) |
| 0.0 | 0.1 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.0 | 0.4 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
| 0.0 | 0.5 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
| 0.0 | 1.0 | GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway(GO:2001243) |
| 0.0 | 1.4 | GO:0046488 | phosphatidylinositol metabolic process(GO:0046488) |
| 0.0 | 0.8 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 6.2 | GO:0060187 | cell pole(GO:0060187) |
| 0.4 | 2.2 | GO:0031523 | Myb complex(GO:0031523) |
| 0.4 | 2.1 | GO:0008623 | CHRAC(GO:0008623) |
| 0.4 | 2.4 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.3 | 7.2 | GO:0002102 | podosome(GO:0002102) |
| 0.2 | 0.7 | GO:0042585 | germinal vesicle(GO:0042585) |
| 0.2 | 4.2 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.1 | 1.8 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 0.7 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.1 | 1.2 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.1 | 0.8 | GO:0098536 | deuterosome(GO:0098536) |
| 0.1 | 0.3 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
| 0.1 | 0.5 | GO:0072487 | MSL complex(GO:0072487) |
| 0.1 | 0.4 | GO:0071438 | NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438) |
| 0.1 | 0.7 | GO:0030478 | actin cap(GO:0030478) |
| 0.1 | 0.4 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 0.1 | 1.4 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 5.7 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.1 | 0.6 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.0 | 0.5 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.0 | 1.5 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 0.5 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.0 | 4.2 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.0 | 1.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.0 | 0.6 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 1.1 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.0 | 0.5 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.0 | 0.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.0 | 0.4 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 0.4 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.0 | 2.1 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 0.5 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.6 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) microbody part(GO:0044438) peroxisomal part(GO:0044439) |
| 0.0 | 0.2 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.0 | 0.4 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 0.8 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.0 | 1.2 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 2.2 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 0.2 | GO:0060091 | kinocilium(GO:0060091) |
| 0.0 | 0.3 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 0.3 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 2.6 | GO:0043296 | apical junction complex(GO:0043296) |
| 0.0 | 0.0 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.0 | 0.2 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.0 | 0.8 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 0.1 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 0.0 | 0.2 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 0.6 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 1.1 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 1.0 | 7.3 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.6 | 1.7 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.6 | 2.2 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.5 | 1.4 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.4 | 1.8 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.3 | 5.1 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.3 | 4.2 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
| 0.3 | 1.1 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
| 0.2 | 1.4 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.2 | 1.9 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.2 | 2.6 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.2 | 2.8 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.2 | 0.9 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.2 | 0.5 | GO:0047256 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
| 0.2 | 0.8 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.1 | 1.0 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.1 | 4.1 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 2.8 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.1 | 0.4 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.1 | 0.9 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.1 | 0.7 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.1 | 2.3 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.1 | 0.5 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.1 | 1.2 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.1 | 3.9 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 0.6 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 0.9 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) |
| 0.1 | 0.3 | GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
| 0.1 | 1.1 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.1 | 1.4 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 0.4 | GO:0031628 | opioid receptor binding(GO:0031628) |
| 0.1 | 2.4 | GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) |
| 0.1 | 0.4 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.1 | 2.4 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 0.5 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.1 | 0.5 | GO:0051718 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718) |
| 0.1 | 0.3 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.1 | 1.6 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
| 0.1 | 0.4 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.1 | 0.4 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 3.3 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.1 | 1.9 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 1.3 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 1.8 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 0.8 | GO:0015197 | peptide transporter activity(GO:0015197) |
| 0.0 | 0.2 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.0 | 0.3 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.0 | 1.3 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 0.3 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.0 | 0.3 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.0 | 0.3 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.0 | 0.5 | GO:0048185 | activin binding(GO:0048185) |
| 0.0 | 0.9 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.2 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 0.0 | 1.7 | GO:0044824 | integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824) |
| 0.0 | 0.1 | GO:0019808 | polyamine binding(GO:0019808) |
| 0.0 | 0.3 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
| 0.0 | 0.3 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.6 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 1.6 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.0 | 0.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.5 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.0 | 0.3 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.0 | 1.1 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 12.0 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 0.4 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.0 | 0.9 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 0.4 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.0 | 0.7 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
| 0.0 | 0.4 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.0 | 0.9 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 1.3 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 5.1 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.0 | 0.8 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 0.5 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 3.5 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.0 | 0.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.3 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.1 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.0 | 0.6 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.6 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 7.4 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
| 0.0 | 0.4 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 1.0 | GO:0061659 | ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
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