Motif ID: Msx1_Lhx9_Barx1_Rax_Dlx6

Z-value: 0.629


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Lhx9mm10_v2_chr1_-_138848576_138848603-0.563.5e-06Click!
Raxmm10_v2_chr18_-_65939048_65939089-0.541.0e-05Click!
Msx1mm10_v2_chr5_-_37824580_37824584-0.302.3e-02Click!
Dlx6mm10_v2_chr6_+_6863269_6863334-0.211.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Msx1_Lhx9_Barx1_Rax_Dlx6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_136171722 8.442 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr5_-_134747241 8.038 ENSMUST00000015138.9
Eln
elastin
chr5_-_62766153 7.773 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_+_118478344 7.750 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr9_+_118478182 7.503 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr8_+_54954728 6.032 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr2_+_116067213 5.750 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr4_-_14621805 5.101 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr16_+_45093611 5.032 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr9_-_40346290 4.842 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr7_+_126950518 4.616 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr1_-_155417394 4.333 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr19_+_26749726 4.003 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_155417283 3.959 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr7_+_126950687 3.868 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr2_-_116067391 3.624 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr16_+_42907563 3.180 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr4_-_14621494 3.119 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr18_+_23415400 3.069 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr2_-_45117349 3.028 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr6_-_126645784 3.021 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr17_-_90088343 2.980 ENSMUST00000173917.1
Nrxn1
neurexin I
chr10_+_39612934 2.896 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr7_+_126950837 2.831 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr11_-_98053415 2.775 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr11_-_87359011 2.664 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr17_+_3397189 2.647 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr16_-_74411292 2.634 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr15_-_66812593 2.549 ENSMUST00000100572.3
Sla
src-like adaptor
chr1_-_158356258 2.495 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr3_+_68572245 2.471 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr14_-_118052235 2.454 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr12_+_49382791 2.451 ENSMUST00000179669.1
Foxg1
forkhead box G1
chr1_+_104768510 2.238 ENSMUST00000062528.8
Cdh20
cadherin 20
chr12_-_83487708 2.199 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr18_-_37969742 2.192 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
Fchsd1


FCH and double SH3 domains 1


chr17_-_49564262 2.101 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr5_-_77115145 2.095 ENSMUST00000081964.5
Hopx
HOP homeobox
chr5_-_62765618 1.914 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_-_26210553 1.839 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr18_+_57468478 1.839 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr15_+_21111452 1.720 ENSMUST00000075132.6
Cdh12
cadherin 12
chr10_-_25200110 1.717 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr16_-_45724600 1.706 ENSMUST00000096057.4
Tagln3
transgelin 3
chr16_-_42340595 1.655 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr5_-_123141067 1.645 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr1_-_78968079 1.636 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr8_-_109251698 1.588 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr13_+_23574381 1.561 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr16_-_97170707 1.493 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr7_-_81493725 1.484 ENSMUST00000119121.1
Ap3b2
adaptor-related protein complex 3, beta 2 subunit
chr14_-_79771305 1.408 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chr1_-_79440039 1.392 ENSMUST00000049972.4
Scg2
secretogranin II
chr10_+_73821857 1.372 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr3_+_55461758 1.363 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr6_+_145934113 1.354 ENSMUST00000032383.7
Sspn
sarcospan
chr15_-_8710734 1.307 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_-_14621669 1.291 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr4_+_97777780 1.246 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr15_-_8710409 1.222 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr19_+_26750939 1.213 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_32116040 1.132 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr2_+_20737306 1.123 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr12_-_91849081 1.094 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
Sel1l


sel-1 suppressor of lin-12-like (C. elegans)


chr2_-_77703252 1.083 ENSMUST00000171063.1
Zfp385b
zinc finger protein 385B
chr6_+_63255971 1.058 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr9_+_45370185 1.056 ENSMUST00000085939.6
Fxyd6
FXYD domain-containing ion transport regulator 6
chr17_-_29888570 0.993 ENSMUST00000171691.1
Mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr13_+_83732438 0.977 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr4_+_108719649 0.975 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr3_+_62419668 0.952 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr10_+_127421124 0.909 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chr12_+_74297474 0.900 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr9_-_103222063 0.891 ENSMUST00000170904.1
Trf
transferrin
chr16_-_63864114 0.877 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr2_-_79456750 0.867 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr18_+_37819543 0.819 ENSMUST00000055935.5
Pcdhga9
protocadherin gamma subfamily A, 9
chrX_+_166344692 0.814 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chrX_-_143933204 0.792 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr3_+_96268654 0.721 ENSMUST00000098843.2
Hist2h3b
histone cluster 2, H3b
chr13_+_42680565 0.719 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr11_+_102285161 0.697 ENSMUST00000156326.1
Tmub2
transmembrane and ubiquitin-like domain containing 2
chr6_+_8948608 0.691 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr17_+_75005523 0.687 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr5_+_13398688 0.662 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_-_6721606 0.661 ENSMUST00000150624.2
ENSMUST00000142941.1
ENSMUST00000100429.4
ENSMUST00000182879.1
Celf2



CUGBP, Elav-like family member 2



chr2_+_71528657 0.649 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr8_+_83666827 0.638 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr13_+_16011851 0.618 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr3_+_86070915 0.594 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr11_-_119547744 0.579 ENSMUST00000026670.4
Nptx1
neuronal pentraxin 1
chr16_-_4880284 0.570 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr1_-_152625212 0.570 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chrX_-_143933089 0.563 ENSMUST00000087313.3
Dcx
doublecortin
chr6_-_57535422 0.552 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr15_-_67113909 0.547 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr2_-_64975762 0.528 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr13_-_113663670 0.528 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr8_+_107031218 0.523 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr3_+_90600203 0.513 ENSMUST00000001047.7
S100a3
S100 calcium binding protein A3
chr10_+_127420867 0.507 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr7_+_29071597 0.505 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr13_-_23574196 0.490 ENSMUST00000105106.1
Hist1h2bf
histone cluster 1, H2bf
chr7_-_73541738 0.486 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr3_+_151437887 0.473 ENSMUST00000046977.7
Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr10_+_127420334 0.466 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chr5_-_23616528 0.463 ENSMUST00000088392.4
Srpk2
serine/arginine-rich protein specific kinase 2
chr14_-_108914237 0.462 ENSMUST00000100322.2
Slitrk1
SLIT and NTRK-like family, member 1
chr2_-_6721890 0.456 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr4_-_155056784 0.449 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr12_+_38780284 0.409 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr3_-_94412883 0.408 ENSMUST00000181305.1
1700040D17Rik
RIKEN cDNA 1700040D17 gene
chr12_+_111814170 0.390 ENSMUST00000021714.7
Zfyve21
zinc finger, FYVE domain containing 21
chr4_+_21848039 0.388 ENSMUST00000098238.2
ENSMUST00000108229.1
Sfrs18

serine/arginine-rich splicing factor 18

chr4_+_5724304 0.388 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr11_+_116843278 0.387 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr5_-_137684665 0.365 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
Agfg2


ArfGAP with FG repeats 2


chr2_+_106693185 0.360 ENSMUST00000111063.1
Mpped2
metallophosphoesterase domain containing 2
chr5_-_137531204 0.355 ENSMUST00000150063.2
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr2_-_33086366 0.344 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr15_+_92597104 0.342 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr3_+_66219909 0.333 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr2_+_73271925 0.318 ENSMUST00000090813.5
Sp9
trans-acting transcription factor 9
chr8_+_56551090 0.317 ENSMUST00000040218.5
ENSMUST00000110322.3
Fbxo8

F-box protein 8

chr12_+_38780817 0.317 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr5_+_14025305 0.303 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr9_+_61372359 0.299 ENSMUST00000178113.1
ENSMUST00000159386.1
Tle3

transducin-like enhancer of split 3, homolog of Drosophila E(spl)

chr17_-_29007925 0.297 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chr13_+_80883403 0.295 ENSMUST00000099356.2
Arrdc3
arrestin domain containing 3
chr12_-_48559971 0.293 ENSMUST00000169406.1
Gm1818
predicted gene 1818
chrX_-_75416533 0.290 ENSMUST00000033542.4
Mtcp1
mature T cell proliferation 1
chr1_+_132298606 0.279 ENSMUST00000046071.4
Klhdc8a
kelch domain containing 8A
chr7_+_64501949 0.274 ENSMUST00000138829.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr19_+_25672408 0.272 ENSMUST00000053068.5
Dmrt2
doublesex and mab-3 related transcription factor 2
chr7_-_45103747 0.268 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr13_+_36117349 0.253 ENSMUST00000021857.5
ENSMUST00000099582.2
Fars2

phenylalanine-tRNA synthetase 2 (mitochondrial)

chr15_+_79690869 0.252 ENSMUST00000046463.8
Gtpbp1
GTP binding protein 1
chr17_+_46161021 0.249 ENSMUST00000024748.7
ENSMUST00000172170.1
Gtpbp2

GTP binding protein 2

chr8_-_84662841 0.248 ENSMUST00000060427.4
Ier2
immediate early response 2
chr5_+_34999070 0.235 ENSMUST00000114280.1
Rgs12
regulator of G-protein signaling 12
chr10_+_18469958 0.234 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr1_-_172027251 0.219 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr5_-_122989260 0.219 ENSMUST00000118027.1
Kdm2b
lysine (K)-specific demethylase 2B
chr13_-_36117269 0.215 ENSMUST00000053265.6
Lyrm4
LYR motif containing 4
chr5_+_34999046 0.204 ENSMUST00000114281.1
Rgs12
regulator of G-protein signaling 12
chr7_+_102210335 0.192 ENSMUST00000140631.1
ENSMUST00000120879.1
ENSMUST00000146996.1
Pgap2


post-GPI attachment to proteins 2


chr15_-_79285502 0.189 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr5_+_64812336 0.189 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr2_-_6722187 0.185 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr5_-_137531952 0.178 ENSMUST00000140139.1
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr3_+_61364507 0.171 ENSMUST00000049064.2
Rap2b
RAP2B, member of RAS oncogene family
chr12_+_38783503 0.162 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr3_+_32436151 0.158 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr5_-_122989086 0.155 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr8_+_121116163 0.151 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr5_+_34999111 0.143 ENSMUST00000114283.1
Rgs12
regulator of G-protein signaling 12
chr6_-_102464667 0.139 ENSMUST00000032159.6
Cntn3
contactin 3
chr18_-_24603791 0.139 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr4_-_97584612 0.138 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr8_+_4238733 0.135 ENSMUST00000110998.2
ENSMUST00000062686.4
Map2k7

mitogen-activated protein kinase kinase 7

chr7_+_64501687 0.134 ENSMUST00000032732.8
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr9_-_71163224 0.131 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr4_+_154964117 0.122 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr7_+_25681158 0.119 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr16_-_92400067 0.117 ENSMUST00000023672.8
Rcan1
regulator of calcineurin 1
chr9_+_17030045 0.115 ENSMUST00000164523.2
Gm5611
predicted gene 5611
chr8_+_45658666 0.112 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr7_-_73537621 0.111 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr18_-_24603464 0.100 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr3_-_59220150 0.100 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr8_+_45658731 0.088 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr11_-_97700327 0.066 ENSMUST00000018681.7
Pcgf2
polycomb group ring finger 2
chr7_+_64502090 0.062 ENSMUST00000137732.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chrM_+_2743 0.057 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chrX_-_95658379 0.050 ENSMUST00000119640.1
Zc4h2
zinc finger, C4H2 domain containing
chr8_-_84846860 0.027 ENSMUST00000003912.6
Calr
calreticulin
chr13_+_118714678 0.027 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr4_-_97584605 0.018 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr12_+_21417872 0.016 ENSMUST00000180671.1
Gm4419
predicted gene 4419
chr7_-_99141068 0.008 ENSMUST00000037968.8
Uvrag
UV radiation resistance associated gene
chr5_-_122988533 0.007 ENSMUST00000086200.4
ENSMUST00000156474.1
Kdm2b

lysine (K)-specific demethylase 2B

chr16_-_76373827 0.006 ENSMUST00000121927.1
Nrip1
nuclear receptor interacting protein 1
chr12_+_55089202 0.005 ENSMUST00000021407.10
Srp54a
signal recognition particle 54A
chrX_-_95658416 0.004 ENSMUST00000044382.6
Zc4h2
zinc finger, C4H2 domain containing
chr4_+_116720920 0.003 ENSMUST00000045542.6
ENSMUST00000106459.1
Tesk2

testis-specific kinase 2


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.3 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.4 8.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.4 9.5 GO:0019532 oxalate transport(GO:0019532)
1.0 3.0 GO:0050975 sensory perception of touch(GO:0050975)
0.9 2.6 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.8 2.5 GO:0021852 pyramidal neuron migration(GO:0021852)
0.6 2.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.6 3.0 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.6 5.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.6 8.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.5 3.0 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.5 1.5 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.5 11.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.4 1.7 GO:0016198 axon choice point recognition(GO:0016198)
0.4 2.5 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.3 2.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.3 0.9 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.3 1.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.3 1.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.2 1.0 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 2.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 0.9 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.2 0.6 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.2 1.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 0.5 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 3.1 GO:0001553 luteinization(GO:0001553)
0.2 6.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 2.9 GO:0048305 immunoglobulin secretion(GO:0048305)
0.2 1.4 GO:0050957 equilibrioception(GO:0050957)
0.1 0.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.6 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.5 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.9 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.1 0.3 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.3 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.1 3.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.1 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 8.5 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 1.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.3 GO:0061055 myotome development(GO:0061055)
0.1 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 1.2 GO:0060074 synapse maturation(GO:0060074)
0.1 2.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.2 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278) regulation of vascular wound healing(GO:0061043) glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.0 0.1 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.6 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 4.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.0 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.7 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.1 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 1.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 1.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0060915 fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915) Harderian gland development(GO:0070384)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0015791 polyol transport(GO:0015791) bile acid secretion(GO:0032782)
0.0 3.5 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 2.3 GO:0098792 xenophagy(GO:0098792)
0.0 0.3 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 2.1 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 1.2 GO:0048706 embryonic skeletal system development(GO:0048706)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0071953 elastic fiber(GO:0071953)
0.8 8.4 GO:0043083 synaptic cleft(GO:0043083)
0.3 5.0 GO:0005614 interstitial matrix(GO:0005614)
0.3 7.4 GO:0071565 nBAF complex(GO:0071565)
0.3 4.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 0.7 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 0.6 GO:0043512 inhibin A complex(GO:0043512)
0.2 2.5 GO:0043205 fibril(GO:0043205)
0.2 2.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 3.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.5 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.8 GO:0097433 dense body(GO:0097433)
0.1 1.4 GO:0031045 dense core granule(GO:0031045)
0.1 1.7 GO:0031527 filopodium membrane(GO:0031527)
0.1 2.6 GO:0030673 axolemma(GO:0030673)
0.1 4.1 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 0.5 GO:0090543 Flemming body(GO:0090543)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 3.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 2.9 GO:0005768 endosome(GO:0005768)
0.0 1.4 GO:0032420 stereocilium(GO:0032420)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 8.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 1.1 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.7 GO:0030424 axon(GO:0030424)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 7.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 2.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0045202 synapse(GO:0045202)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 8.3 GO:0001618 virus receptor activity(GO:0001618)
0.9 9.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.8 8.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.5 2.5 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.3 2.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 16.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 3.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 1.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 7.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 9.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 5.0 GO:0001968 fibronectin binding(GO:0001968)
0.2 2.5 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 0.7 GO:0050436 microfibril binding(GO:0050436)
0.2 0.6 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.9 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.3 GO:0046790 virion binding(GO:0046790)
0.1 3.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 4.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 3.0 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.7 GO:0016208 AMP binding(GO:0016208)
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.1 1.4 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 6.0 GO:0005262 calcium channel activity(GO:0005262)
0.1 1.1 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.7 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 1.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 2.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 2.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.3 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)