Motif ID: Myb

Z-value: 2.108


Transcription factors associated with Myb:

Gene SymbolEntrez IDGene Name
Myb ENSMUSG00000019982.8 Myb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybmm10_v2_chr10_-_21160925_211609840.782.6e-13Click!


Activity profile for motif Myb.

activity profile for motif Myb


Sorted Z-values histogram for motif Myb

Sorted Z-values for motif Myb



Network of associatons between targets according to the STRING database.



First level regulatory network of Myb

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_64851991 13.861 ENSMUST00000067744.7
Cggbp1
CGG triplet repeat binding protein 1
chr18_+_60925612 13.585 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr5_+_123749696 11.883 ENSMUST00000031366.7
Kntc1
kinetochore associated 1
chr2_-_127831817 11.780 ENSMUST00000028858.7
Bub1
budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
chr11_-_69921057 11.747 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
Eif5a


eukaryotic translation initiation factor 5A


chr2_+_118814195 11.523 ENSMUST00000110842.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chr2_+_118814237 11.482 ENSMUST00000028803.7
ENSMUST00000126045.1
Knstrn

kinetochore-localized astrin/SPAG5 binding

chr17_-_70851189 11.262 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chrX_+_58030999 10.857 ENSMUST00000088631.4
ENSMUST00000088629.3
Zic3

zinc finger protein of the cerebellum 3

chr11_-_69921329 10.749 ENSMUST00000108613.3
ENSMUST00000043419.3
ENSMUST00000070996.4
Eif5a


eukaryotic translation initiation factor 5A


chr9_+_72438534 10.638 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr2_+_118813995 10.634 ENSMUST00000134661.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chr4_-_118437331 10.541 ENSMUST00000006565.6
Cdc20
cell division cycle 20
chr9_+_72438519 10.527 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr7_-_144939823 10.419 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr16_-_46496955 10.202 ENSMUST00000023335.6
ENSMUST00000023334.8
Pvrl3

poliovirus receptor-related 3

chr11_-_69921190 9.661 ENSMUST00000108607.1
Eif5a
eukaryotic translation initiation factor 5A
chr11_-_69920892 9.525 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr10_+_84838143 9.426 ENSMUST00000095388.4
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr1_-_191575534 9.189 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 164 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.6 39.9 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
2.2 39.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 23.7 GO:0007067 mitotic nuclear division(GO:0007067)
1.3 21.2 GO:0070986 left/right axis specification(GO:0070986)
2.6 21.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
1.2 18.9 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 18.9 GO:0043484 regulation of RNA splicing(GO:0043484)
1.2 18.6 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
1.1 17.7 GO:0022027 interkinetic nuclear migration(GO:0022027) astral microtubule organization(GO:0030953)
2.9 17.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.8 16.1 GO:0001522 pseudouridine synthesis(GO:0001522)
0.5 14.5 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
3.6 14.3 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.5 13.9 GO:0007099 centriole replication(GO:0007099)
2.7 13.4 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.5 13.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 13.0 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.8 12.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.6 11.8 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.6 11.7 GO:0000920 cell separation after cytokinesis(GO:0000920)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 99 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.1 40.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 36.7 GO:0005813 centrosome(GO:0005813)
0.3 34.8 GO:0000776 kinetochore(GO:0000776)
1.1 33.6 GO:0035371 microtubule plus-end(GO:0035371)
1.2 31.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 24.5 GO:0005730 nucleolus(GO:0005730)
0.3 21.1 GO:0005882 intermediate filament(GO:0005882)
0.3 17.4 GO:0005871 kinesin complex(GO:0005871)
0.8 16.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.5 16.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 15.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
1.0 14.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 13.4 GO:0005643 nuclear pore(GO:0005643)
4.0 11.9 GO:1990423 RZZ complex(GO:1990423)
2.9 11.8 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.6 11.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 10.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 10.1 GO:0005814 centriole(GO:0005814)
1.4 9.5 GO:0001940 male pronucleus(GO:0001940)
0.4 9.3 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 119 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.1 39.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 23.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.8 18.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.3 17.4 GO:0003777 microtubule motor activity(GO:0003777)
1.3 16.1 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
3.6 14.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.5 14.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 12.8 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 12.7 GO:0042393 histone binding(GO:0042393)
0.1 11.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.5 11.3 GO:0070410 co-SMAD binding(GO:0070410)
2.8 11.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 11.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
3.7 11.0 GO:0097100 supercoiled DNA binding(GO:0097100)
1.8 10.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.4 10.4 GO:0070064 proline-rich region binding(GO:0070064)
0.2 10.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.4 10.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 10.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.6 9.7 GO:0044183 protein binding involved in protein folding(GO:0044183)