Motif ID: Mybl1

Z-value: 1.189


Transcription factors associated with Mybl1:

Gene SymbolEntrez IDGene Name
Mybl1 ENSMUSG00000025912.10 Mybl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybl1mm10_v2_chr1_-_9700209_9700329-0.038.0e-01Click!


Activity profile for motif Mybl1.

activity profile for motif Mybl1


Sorted Z-values histogram for motif Mybl1

Sorted Z-values for motif Mybl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Mybl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_32276400 9.933 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_-_69921190 8.178 ENSMUST00000108607.1
 Eif5a
eukaryotic translation initiation factor 5A
chr14_-_48662740 7.787 ENSMUST00000122009.1
 Otx2
orthodenticle homolog 2 (Drosophila)
chr7_+_126862431 7.400 ENSMUST00000132808.1
 Hirip3
HIRA interacting protein 3
chrX_-_106485214 7.225 ENSMUST00000039447.7
 Fndc3c1
fibronectin type III domain containing 3C1
chr9_+_78191966 7.124 ENSMUST00000034903.5
 Gsta4
glutathione S-transferase, alpha 4
chr2_+_118814195 6.125 ENSMUST00000110842.1
 Knstrn
kinetochore-localized astrin/SPAG5 binding
chr2_+_118814237 6.027 ENSMUST00000028803.7
ENSMUST00000126045.1
 Knstrn

kinetochore-localized astrin/SPAG5 binding

chr8_+_83715504 6.025 ENSMUST00000109810.1
 Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr11_-_106999369 5.839 ENSMUST00000106768.1
ENSMUST00000144834.1
 Kpna2

karyopherin (importin) alpha 2

chrX_-_102157065 5.387 ENSMUST00000056904.2
 Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr11_+_59306920 5.383 ENSMUST00000000128.3
ENSMUST00000108783.3
 Wnt9a

wingless-type MMTV integration site 9A

chr2_+_118813995 5.315 ENSMUST00000134661.1
 Knstrn
kinetochore-localized astrin/SPAG5 binding
chr11_-_69921329 5.242 ENSMUST00000108613.3
ENSMUST00000043419.3
ENSMUST00000070996.4
 Eif5a


eukaryotic translation initiation factor 5A


chr4_+_65124174 5.210 ENSMUST00000084501.3
 Pappa
pregnancy-associated plasma protein A
chr9_+_7764041 5.202 ENSMUST00000052865.9
 Tmem123
transmembrane protein 123
chr19_+_60144682 5.198 ENSMUST00000065383.4
 E330013P04Rik
RIKEN cDNA E330013P04 gene
chr17_+_29093763 5.071 ENSMUST00000023829.6
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr17_-_26095487 4.954 ENSMUST00000025007.5
 Nme4
NME/NM23 nucleoside diphosphate kinase 4
chr7_+_144915100 4.914 ENSMUST00000128057.1
 Oraov1
oral cancer overexpressed 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 274 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 20.6 GO:0007067 mitotic nuclear division(GO:0007067)
3.4 20.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
1.0 17.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.7 16.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 13.1 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
2.0 9.9 GO:0015671 oxygen transport(GO:0015671)
1.9 7.8 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.9 7.4 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 7.0 GO:0051384 response to glucocorticoid(GO:0051384)
0.1 7.0 GO:0051225 spindle assembly(GO:0051225)
2.2 6.6 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 6.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
1.3 6.4 GO:0019659 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.8 6.3 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.7 6.3 GO:0044458 motile cilium assembly(GO:0044458)
1.5 6.2 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
1.5 6.1 GO:0003360 brainstem development(GO:0003360)
0.2 6.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.0 5.9 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.4 5.4 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 144 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 21.6 GO:0005642 annulate lamellae(GO:0005642)
0.6 21.0 GO:0035371 microtubule plus-end(GO:0035371)
0.3 20.9 GO:0005643 nuclear pore(GO:0005643)
0.0 20.2 GO:0005615 extracellular space(GO:0005615)
0.1 20.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 15.6 GO:0005730 nucleolus(GO:0005730)
1.4 11.5 GO:0005833 hemoglobin complex(GO:0005833)
0.1 8.8 GO:0000776 kinetochore(GO:0000776)
0.0 8.5 GO:0005925 focal adhesion(GO:0005925)
0.4 8.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 7.8 GO:0005635 nuclear envelope(GO:0005635)
0.3 7.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 7.2 GO:0035861 site of double-strand break(GO:0035861)
0.2 7.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3 7.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 6.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
2.0 6.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.7 5.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.9 5.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 4.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 190 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 28.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.6 21.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.6 16.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 15.2 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 13.9 GO:0044822 poly(A) RNA binding(GO:0044822)
2.0 9.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 9.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 7.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.3 7.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.4 6.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 6.4 GO:0070491 repressing transcription factor binding(GO:0070491)
1.3 6.3 GO:0032027 myosin light chain binding(GO:0032027)
0.8 6.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
1.0 6.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 6.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
1.2 5.9 GO:0042610 CD8 receptor binding(GO:0042610)
0.8 5.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.4 5.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 4.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 4.7 GO:0005179 hormone activity(GO:0005179)