Motif ID: Mybl2

Z-value: 1.884


Transcription factors associated with Mybl2:

Gene SymbolEntrez IDGene Name
Mybl2 ENSMUSG00000017861.5 Mybl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybl2mm10_v2_chr2_+_163054682_1630546930.895.1e-21Click!


Activity profile for motif Mybl2.

activity profile for motif Mybl2


Sorted Z-values histogram for motif Mybl2

Sorted Z-values for motif Mybl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Mybl2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_90002881 14.968 ENSMUST00000020864.8
 Pctp
phosphatidylcholine transfer protein
chr1_-_169531343 13.196 ENSMUST00000028000.7
 Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr19_-_41802028 13.173 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
 Arhgap19


Rho GTPase activating protein 19


chr18_+_5591860 12.422 ENSMUST00000025081.5
ENSMUST00000159390.1
 Zeb1

zinc finger E-box binding homeobox 1

chrX_-_143827391 12.162 ENSMUST00000087316.5
 Capn6
calpain 6
chr11_-_106999369 12.001 ENSMUST00000106768.1
ENSMUST00000144834.1
 Kpna2

karyopherin (importin) alpha 2

chr9_-_79977782 11.677 ENSMUST00000093811.4
 Filip1
filamin A interacting protein 1
chr4_-_116627921 11.327 ENSMUST00000030456.7
 Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr1_-_169531447 10.931 ENSMUST00000111368.1
 Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr13_-_81710937 10.810 ENSMUST00000161920.1
ENSMUST00000048993.5
 Polr3g

polymerase (RNA) III (DNA directed) polypeptide G

chr10_+_84838143 9.812 ENSMUST00000095388.4
 Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr4_-_116627478 9.607 ENSMUST00000081182.4
ENSMUST00000030457.5
 Nasp

nuclear autoantigenic sperm protein (histone-binding)

chr13_+_92354783 9.053 ENSMUST00000022218.4
 Dhfr
dihydrofolate reductase
chr1_+_191821444 8.797 ENSMUST00000027931.7
 Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr11_-_106999482 8.709 ENSMUST00000018506.6
 Kpna2
karyopherin (importin) alpha 2
chr1_+_57995971 8.680 ENSMUST00000027202.8
 Sgol2
shugoshin-like 2 (S. pombe)
chr2_+_13573927 8.598 ENSMUST00000141365.1
ENSMUST00000028062.2
 Vim

vimentin

chr4_-_124936852 8.561 ENSMUST00000030690.5
ENSMUST00000084296.3
 Cdca8

cell division cycle associated 8

chr14_-_67715585 8.544 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
 Cdca2


cell division cycle associated 2


chr19_+_53142756 8.525 ENSMUST00000050096.7
 Add3
adducin 3 (gamma)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 189 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 20.9 GO:0043486 histone exchange(GO:0043486)
0.6 20.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.7 18.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 15.0 GO:0015914 phospholipid transport(GO:0015914)
0.8 14.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.3 14.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
2.8 13.9 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.4 12.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)
1.4 12.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
2.4 12.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
1.0 12.0 GO:0019985 translesion synthesis(GO:0019985)
0.4 11.7 GO:0007099 centriole replication(GO:0007099)
2.7 10.9 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
1.7 9.9 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
2.0 9.8 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.9 9.6 GO:0070836 caveola assembly(GO:0070836)
0.2 9.4 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
1.7 8.6 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.5 8.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 8.5 GO:0042493 response to drug(GO:0042493)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 107 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.0 30.0 GO:0031262 Ndc80 complex(GO:0031262)
0.3 22.2 GO:0005643 nuclear pore(GO:0005643)
0.1 18.9 GO:0005635 nuclear envelope(GO:0005635)
0.3 17.3 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.2 14.4 GO:0005871 kinesin complex(GO:0005871)
0.5 14.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.4 14.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 12.2 GO:0005876 spindle microtubule(GO:0005876)
0.9 12.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 11.6 GO:0044454 nuclear chromosome part(GO:0044454)
1.6 11.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 11.1 GO:0005681 spliceosomal complex(GO:0005681)
0.5 9.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 9.6 GO:0005667 transcription factor complex(GO:0005667)
0.4 9.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.6 9.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 8.9 GO:0000922 spindle pole(GO:0000922)
0.0 8.8 GO:0005615 extracellular space(GO:0005615)
2.1 8.6 GO:0045098 type III intermediate filament(GO:0045098)
1.7 8.6 GO:0032133 chromosome passenger complex(GO:0032133)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 146 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 21.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.7 19.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 17.8 GO:0042393 histone binding(GO:0042393)
2.5 15.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.2 14.4 GO:0003777 microtubule motor activity(GO:0003777)
0.2 14.3 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 13.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.3 12.4 GO:0070888 E-box binding(GO:0070888)
0.6 12.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 11.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.5 9.9 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 9.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.6 9.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 9.4 GO:0019902 phosphatase binding(GO:0019902)
3.0 9.1 GO:0051870 methotrexate binding(GO:0051870)
2.1 8.6 GO:1990254 keratin filament binding(GO:1990254)
0.1 8.5 GO:0005080 protein kinase C binding(GO:0005080)
1.9 7.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.1 7.5 GO:0034452 dynactin binding(GO:0034452)
1.1 7.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)