Motif ID: Nfat5

Z-value: 0.936


Transcription factors associated with Nfat5:

Gene SymbolEntrez IDGene Name
Nfat5 ENSMUSG00000003847.10 Nfat5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfat5mm10_v2_chr8_+_107293463_1072934830.201.3e-01Click!


Activity profile for motif Nfat5.

activity profile for motif Nfat5


Sorted Z-values histogram for motif Nfat5

Sorted Z-values for motif Nfat5



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfat5

PNG image of the network

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Top targets:


Showing 1 to 20 of 83 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_97417730 9.820 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr6_+_120773633 7.806 ENSMUST00000112682.2
 Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr5_+_139423151 7.012 ENSMUST00000066211.4
 Gper1
G protein-coupled estrogen receptor 1
chr9_+_92457369 7.008 ENSMUST00000034941.7
 Plscr4
phospholipid scramblase 4
chr6_-_58907120 6.102 ENSMUST00000059539.3
 Nap1l5
nucleosome assembly protein 1-like 5
chr7_+_110773658 5.967 ENSMUST00000143786.1
 Ampd3
adenosine monophosphate deaminase 3
chr1_+_45981548 5.222 ENSMUST00000085632.2
 Rpl23a-ps1
ribosomal protein 23A, pseudogene 1
chr5_-_104021919 5.082 ENSMUST00000031251.9
 Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr7_+_110774240 4.943 ENSMUST00000147587.1
 Ampd3
adenosine monophosphate deaminase 3
chr1_+_24678536 4.846 ENSMUST00000095062.3
 Lmbrd1
LMBR1 domain containing 1
chr6_-_101377897 4.722 ENSMUST00000075994.6
 Pdzrn3
PDZ domain containing RING finger 3
chr4_-_82505749 4.625 ENSMUST00000107245.2
ENSMUST00000107246.1
 Nfib

nuclear factor I/B

chr8_-_107403197 4.429 ENSMUST00000003947.8
 Nqo1
NAD(P)H dehydrogenase, quinone 1
chrX_-_155216338 4.353 ENSMUST00000112551.3
 Sat1
spermidine/spermine N1-acetyl transferase 1
chr14_-_101609033 4.353 ENSMUST00000161991.1
ENSMUST00000100340.3
 Tbc1d4

TBC1 domain family, member 4

chr5_-_104021799 4.303 ENSMUST00000119025.1
 Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr4_-_82505707 4.135 ENSMUST00000107248.1
ENSMUST00000107247.1
 Nfib

nuclear factor I/B

chr9_-_29963112 4.095 ENSMUST00000075069.4
 Ntm
neurotrimin
chr15_-_75894474 3.822 ENSMUST00000023237.6
 Naprt1
nicotinate phosphoribosyltransferase domain containing 1
chr7_+_99535652 3.730 ENSMUST00000032995.8
ENSMUST00000162404.1
 Arrb1

arrestin, beta 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 11.0 GO:0008654 phospholipid biosynthetic process(GO:0008654)
1.4 10.9 GO:0032264 IMP salvage(GO:0032264)
0.3 9.8 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.9 9.4 GO:0042447 hormone catabolic process(GO:0042447)
2.2 8.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
2.6 7.8 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
1.1 7.4 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
2.3 7.0 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.1 6.1 GO:0006334 nucleosome assembly(GO:0006334)
0.4 5.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.2 4.8 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 4.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.5 4.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 4.4 GO:0006801 superoxide metabolic process(GO:0006801)
1.1 3.3 GO:0003032 detection of oxygen(GO:0003032) regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
0.2 3.3 GO:0030575 nuclear body organization(GO:0030575)
0.0 3.2 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.2 3.1 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
1.0 3.0 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.7 2.8 GO:0035609 C-terminal protein deglutamylation(GO:0035609)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 18.7 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 18.0 GO:0005829 cytosol(GO:0005829)
0.1 9.4 GO:0005811 lipid particle(GO:0005811)
0.4 8.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 8.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.5 7.4 GO:0031143 pseudopodium(GO:0031143)
0.7 7.0 GO:0044327 dendritic spine membrane(GO:0032591) dendritic spine head(GO:0044327)
0.2 4.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 4.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.1 GO:0031225 anchored component of membrane(GO:0031225)
0.4 3.3 GO:0042382 paraspeckles(GO:0042382)
0.0 3.3 GO:0030315 T-tubule(GO:0030315)
0.0 2.8 GO:0005814 centriole(GO:0005814)
0.0 2.5 GO:0032587 ruffle membrane(GO:0032587)
0.1 2.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.9 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.9 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 1.0 GO:0048787 presynaptic active zone membrane(GO:0048787)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 11.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
1.6 10.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.3 9.4 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
1.5 9.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.3 8.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
2.6 7.8 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
2.5 7.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.9 7.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 6.1 GO:0015293 symporter activity(GO:0015293)
0.7 5.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 5.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.7 4.8 GO:0031419 cobalamin binding(GO:0031419)
0.0 4.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
1.1 4.4 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.8 3.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.8 3.1 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.8 3.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 2.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 2.5 GO:0008013 beta-catenin binding(GO:0008013)
0.2 2.0 GO:0034711 inhibin binding(GO:0034711)