Motif ID: Nfatc3

Z-value: 1.515


Transcription factors associated with Nfatc3:

Gene SymbolEntrez IDGene Name
Nfatc3 ENSMUSG00000031902.9 Nfatc3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfatc3mm10_v2_chr8_+_106059562_1060596230.162.4e-01Click!


Activity profile for motif Nfatc3.

activity profile for motif Nfatc3


Sorted Z-values histogram for motif Nfatc3

Sorted Z-values for motif Nfatc3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfatc3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_80713062 19.123 ENSMUST00000170905.1
ENSMUST00000078049.4
 Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr1_-_162866502 13.435 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr17_-_49564262 12.909 ENSMUST00000057610.6
 Daam2
dishevelled associated activator of morphogenesis 2
chr15_-_79164477 12.350 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr19_+_58670358 11.842 ENSMUST00000057270.7
 Pnlip
pancreatic lipase
chr11_+_63133068 9.670 ENSMUST00000108700.1
 Pmp22
peripheral myelin protein 22
chr1_-_170110491 9.450 ENSMUST00000027985.2
 Ddr2
discoidin domain receptor family, member 2
chr11_+_63132569 8.113 ENSMUST00000108701.1
 Pmp22
peripheral myelin protein 22
chr5_-_62765618 7.947 ENSMUST00000159470.1
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_+_4611971 7.284 ENSMUST00000105590.1
ENSMUST00000067086.7
 Esr1

estrogen receptor 1 (alpha)

chr14_-_16575456 6.760 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta
chr15_+_3270767 6.398 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr6_+_120773633 5.920 ENSMUST00000112682.2
 Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr7_-_134232125 5.848 ENSMUST00000127524.1
 Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr1_-_66863265 5.818 ENSMUST00000027153.5
 Acadl
acyl-Coenzyme A dehydrogenase, long-chain
chr4_-_43523595 5.663 ENSMUST00000107914.3
 Tpm2
tropomyosin 2, beta
chr8_+_104101625 5.574 ENSMUST00000034339.8
 Cdh5
cadherin 5
chr3_-_145649970 5.527 ENSMUST00000029846.3
 Cyr61
cysteine rich protein 61
chr7_-_134232005 5.450 ENSMUST00000134504.1
 Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr18_-_9726670 5.293 ENSMUST00000171339.1
 Gm17430
predicted gene, 17430

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 152 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.4 19.1 GO:0060854 patterning of lymph vessels(GO:0060854)
1.0 17.8 GO:0032060 bleb assembly(GO:0032060)
1.3 13.4 GO:0009404 toxin metabolic process(GO:0009404)
0.1 12.7 GO:0007368 determination of left/right symmetry(GO:0007368)
1.0 12.3 GO:0032808 lacrimal gland development(GO:0032808)
2.0 11.8 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
3.5 10.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
3.3 9.9 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
1.3 9.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
1.2 8.2 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.8 7.3 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.3 7.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
1.4 6.8 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
1.4 6.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.9 6.4 GO:0001887 selenium compound metabolic process(GO:0001887)
1.9 5.6 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.3 5.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
1.7 5.0 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 5.0 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.2 4.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 21.9 GO:0005667 transcription factor complex(GO:0005667)
0.7 17.8 GO:0043218 compact myelin(GO:0043218)
0.1 15.8 GO:0031012 extracellular matrix(GO:0031012)
1.6 12.9 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 10.5 GO:0005829 cytosol(GO:0005829)
1.1 9.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 9.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 8.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 7.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 7.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 5.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.3 4.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.5 4.7 GO:0030478 actin cap(GO:0030478)
0.1 4.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 4.7 GO:0005581 collagen trimer(GO:0005581)
0.6 4.6 GO:0042382 paraspeckles(GO:0042382)
0.2 4.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 4.2 GO:0032432 actin filament bundle(GO:0032432)
0.0 4.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 4.1 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 111 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 19.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.1 16.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 16.2 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
2.7 13.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 13.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
1.1 11.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 10.7 GO:0017048 Rho GTPase binding(GO:0017048)
3.5 10.4 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
1.0 9.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 8.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
2.4 7.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 6.9 GO:0051015 actin filament binding(GO:0051015)
0.3 6.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.3 6.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.4 5.9 GO:0008430 selenium binding(GO:0008430)
0.1 5.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
1.0 5.8 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 5.6 GO:0008013 beta-catenin binding(GO:0008013)
0.1 5.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 5.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)