Motif ID: Nfe2_Bach1_Mafk

Z-value: 0.890

Transcription factors associated with Nfe2_Bach1_Mafk:

Gene SymbolEntrez IDGene Name
Bach1 ENSMUSG00000025612.5 Bach1
Mafk ENSMUSG00000018143.4 Mafk
Nfe2 ENSMUSG00000058794.6 Nfe2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafkmm10_v2_chr5_+_139791513_1397915390.713.3e-10Click!
Nfe2mm10_v2_chr15_-_103251465_103251705-0.471.6e-04Click!
Bach1mm10_v2_chr16_+_87698904_876989590.238.5e-02Click!


Activity profile for motif Nfe2_Bach1_Mafk.

activity profile for motif Nfe2_Bach1_Mafk


Sorted Z-values histogram for motif Nfe2_Bach1_Mafk

Sorted Z-values for motif Nfe2_Bach1_Mafk



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2_Bach1_Mafk

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_5725639 22.512 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr1_-_33907721 13.510 ENSMUST00000115161.1
ENSMUST00000062289.8
 Bend6

BEN domain containing 6

chr2_+_155775333 8.796 ENSMUST00000029141.5
 Mmp24
matrix metallopeptidase 24
chr2_+_136713444 6.545 ENSMUST00000028727.4
ENSMUST00000110098.3
 Snap25

synaptosomal-associated protein 25

chr13_-_54611274 6.122 ENSMUST00000049575.7
 Cltb
clathrin, light polypeptide (Lcb)
chr6_+_5725812 5.706 ENSMUST00000115554.1
ENSMUST00000153942.1
 Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr13_-_54611332 5.513 ENSMUST00000091609.4
 Cltb
clathrin, light polypeptide (Lcb)
chr3_-_116968827 5.300 ENSMUST00000119557.1
 Palmd
palmdelphin
chr5_-_139484420 5.041 ENSMUST00000150992.1
 Zfand2a
zinc finger, AN1-type domain 2A
chr1_+_136131382 4.843 ENSMUST00000075164.4
 Kif21b
kinesin family member 21B
chr3_+_123267445 4.797 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr7_+_127244511 4.721 ENSMUST00000052509.4
 Zfp771
zinc finger protein 771
chr5_-_139484475 4.394 ENSMUST00000110851.1
ENSMUST00000079996.6
 Zfand2a

zinc finger, AN1-type domain 2A

chr17_-_56133817 4.324 ENSMUST00000167545.1
 Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr11_-_50210765 3.641 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
 Sqstm1


sequestosome 1


chr1_-_134235420 3.615 ENSMUST00000038191.6
ENSMUST00000086465.4
 Adora1

adenosine A1 receptor

chr16_+_20694908 3.500 ENSMUST00000056518.6
 Fam131a
family with sequence similarity 131, member A
chr5_-_92348871 3.345 ENSMUST00000038816.6
ENSMUST00000118006.1
 Cxcl10

chemokine (C-X-C motif) ligand 10

chr6_-_13838432 3.322 ENSMUST00000115492.1
 Gpr85
G protein-coupled receptor 85
chrX_+_163911401 3.304 ENSMUST00000140845.1
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 136 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 27.2 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.4 13.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 10.4 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.9 9.5 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.7 8.6 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.4 6.5 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 5.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.6 5.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 5.1 GO:0007018 microtubule-based movement(GO:0007018)
1.2 4.8 GO:0035617 stress granule disassembly(GO:0035617)
0.1 4.7 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.1 4.3 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.8 4.0 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.4 3.9 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.5 3.8 GO:0005513 detection of calcium ion(GO:0005513)
1.2 3.6 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.5 3.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.6 3.4 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.4 3.3 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.1 3.3 GO:0031103 axon regeneration(GO:0031103)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 28.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
1.1 11.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 9.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 8.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 7.9 GO:0071565 nBAF complex(GO:0071565)
1.6 6.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 6.4 GO:0005604 basement membrane(GO:0005604)
0.0 6.0 GO:0043197 dendritic spine(GO:0043197)
0.1 5.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 4.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 4.8 GO:0035253 ciliary rootlet(GO:0035253)
0.1 3.8 GO:0005871 kinesin complex(GO:0005871)
0.0 3.7 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
1.2 3.6 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.2 3.6 GO:0032279 asymmetric synapse(GO:0032279)
0.3 3.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 3.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.2 3.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.8 3.0 GO:0031673 H zone(GO:0031673)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 109 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.6 28.2 GO:0045503 dynein light chain binding(GO:0045503)
0.4 13.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
1.3 11.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 9.7 GO:0003777 microtubule motor activity(GO:0003777)
0.2 8.8 GO:0045296 cadherin binding(GO:0045296)
0.0 7.2 GO:0030695 GTPase regulator activity(GO:0030695)
0.3 6.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 5.6 GO:0017124 SH3 domain binding(GO:0017124)
0.1 5.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 4.6 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 4.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 4.2 GO:0005518 collagen binding(GO:0005518)
0.0 4.2 GO:0008017 microtubule binding(GO:0008017)
0.0 3.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 3.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.5 3.6 GO:0032795 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
1.1 3.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.8 3.2 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 3.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.2 3.1 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)