Motif ID: Nfe2l1_Mafg

Z-value: 1.282

Transcription factors associated with Nfe2l1_Mafg:

Gene SymbolEntrez IDGene Name
Mafg ENSMUSG00000051510.7 Mafg
Mafg ENSMUSG00000053906.4 Mafg
Nfe2l1 ENSMUSG00000038615.11 Nfe2l1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafgmm10_v2_chr11_-_120630516_120630636-0.771.0e-12Click!
Nfe2l1mm10_v2_chr11_-_96824008_968241590.211.1e-01Click!


Activity profile for motif Nfe2l1_Mafg.

activity profile for motif Nfe2l1_Mafg


Sorted Z-values histogram for motif Nfe2l1_Mafg

Sorted Z-values for motif Nfe2l1_Mafg



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2l1_Mafg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 48.943 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chrX_-_141874870 14.956 ENSMUST00000182079.1
 Gm15294
predicted gene 15294
chr1_-_45890078 14.810 ENSMUST00000183590.1
 Gm5269
predicted gene 5269
chr17_+_70929006 12.957 ENSMUST00000092011.6
 Gm16519
predicted gene, 16519
chr7_-_137314394 12.248 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr17_+_78491549 10.782 ENSMUST00000079363.4
 Gm10093
predicted pseudogene 10093
chr12_-_10900296 9.976 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr11_-_33276334 9.291 ENSMUST00000183831.1
 Gm12117
predicted gene 12117
chr12_-_56535047 8.725 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr14_-_76237353 8.425 ENSMUST00000095471.4
 Rps2-ps6
ribosomal protein S2, pseudogene 6
chr9_-_79977782 8.023 ENSMUST00000093811.4
 Filip1
filamin A interacting protein 1
chr3_+_85915722 7.735 ENSMUST00000054148.7
 Gm9790
predicted gene 9790
chr1_-_65051119 7.624 ENSMUST00000161960.1
ENSMUST00000087359.5
 Cryge

crystallin, gamma E

chr12_-_54986363 7.517 ENSMUST00000173433.1
ENSMUST00000173803.1
 Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr4_-_63662910 7.488 ENSMUST00000184252.1
 Gm11214
predicted gene 11214
chrX_+_71663665 7.017 ENSMUST00000070449.5
 Gpr50
G-protein-coupled receptor 50
chr2_+_130277157 6.995 ENSMUST00000028890.8
ENSMUST00000159373.1
 Nop56

NOP56 ribonucleoprotein

chr10_+_52022502 6.271 ENSMUST00000163017.1
ENSMUST00000058347.4
 Vgll2

vestigial like 2 homolog (Drosophila)

chr5_+_128601106 6.158 ENSMUST00000117102.2
 Fzd10
frizzled homolog 10 (Drosophila)
chr10_+_31248140 5.846 ENSMUST00000050717.8
 Gm5422
predicted pseudogene 5422

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 114 entries
Log-likelihood per target Total log-likelihoodTermDescription
8.2 48.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.9 8.7 GO:0021759 globus pallidus development(GO:0021759)
1.1 7.5 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 7.5 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 7.1 GO:0000077 DNA damage checkpoint(GO:0000077)
0.3 7.0 GO:0000154 rRNA modification(GO:0000154)
0.2 6.8 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 6.8 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.8 6.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 6.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 5.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 5.0 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.3 4.9 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
1.6 4.8 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
1.0 4.8 GO:0060594 mammary gland specification(GO:0060594)
0.9 4.7 GO:0097475 motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.8 4.6 GO:0060242 contact inhibition(GO:0060242)
1.1 4.4 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.3 4.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 4.3 GO:0002181 cytoplasmic translation(GO:0002181)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 18.9 GO:0005667 transcription factor complex(GO:0005667)
1.5 7.5 GO:0008623 CHRAC(GO:0008623)
0.9 7.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 6.8 GO:0030863 cortical cytoskeleton(GO:0030863)
0.1 5.0 GO:1990391 DNA repair complex(GO:1990391)
0.1 4.9 GO:0005581 collagen trimer(GO:0005581)
0.2 4.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 4.3 GO:0031012 extracellular matrix(GO:0031012)
0.3 4.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 4.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 3.8 GO:0005811 lipid particle(GO:0005811)
0.2 3.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.8 3.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 3.1 GO:0000502 proteasome complex(GO:0000502)
0.2 3.0 GO:0016460 myosin II complex(GO:0016460)
0.3 2.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 2.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.9 2.7 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.4 2.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.4 2.3 GO:0071817 MMXD complex(GO:0071817)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 86 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 53.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 14.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.7 8.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.8 7.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 7.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
2.3 7.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.6 7.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 6.6 GO:0042802 identical protein binding(GO:0042802)
0.0 6.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.3 6.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 6.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 5.0 GO:0042162 telomeric DNA binding(GO:0042162)
0.8 4.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4 4.9 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.2 4.9 GO:0070064 proline-rich region binding(GO:0070064)
0.5 4.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 4.8 GO:0071837 HMG box domain binding(GO:0071837)
0.2 4.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 4.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.9 4.4 GO:0005047 signal recognition particle binding(GO:0005047)