Motif ID: Nfic_Nfib

Z-value: 2.267

Transcription factors associated with Nfic_Nfib:

Gene SymbolEntrez IDGene Name
Nfib ENSMUSG00000008575.11 Nfib
Nfic ENSMUSG00000055053.11 Nfic

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nficmm10_v2_chr10_-_81427114_814271870.761.8e-12Click!
Nfibmm10_v2_chr4_-_82505274_825053580.453.3e-04Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nfic_Nfib

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_43730593 46.977 ENSMUST00000027217.8
1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr11_+_78324200 43.435 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr6_-_115251839 34.175 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr6_+_135362931 32.012 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr2_-_25469742 30.954 ENSMUST00000114259.2
ENSMUST00000015234.6
Ptgds

prostaglandin D2 synthase (brain)

chr2_-_25470031 30.662 ENSMUST00000114251.1
Ptgds
prostaglandin D2 synthase (brain)
chr8_+_72646679 30.061 ENSMUST00000161386.1
ENSMUST00000093427.4
Nwd1

NACHT and WD repeat domain containing 1

chr8_+_72646728 27.483 ENSMUST00000161254.1
Nwd1
NACHT and WD repeat domain containing 1
chr2_-_164404606 26.160 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
Matn4


matrilin 4


chr10_+_86302854 25.126 ENSMUST00000132307.1
Timp3
tissue inhibitor of metalloproteinase 3
chr11_+_3488275 23.488 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr10_+_57784859 23.335 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr6_+_17306335 22.596 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chr1_-_162859684 22.169 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr16_+_90831113 21.466 ENSMUST00000037539.7
ENSMUST00000099543.3
Eva1c

eva-1 homolog C (C. elegans)

chr4_+_130047840 20.999 ENSMUST00000044565.8
ENSMUST00000132251.1
Col16a1

collagen, type XVI, alpha 1

chr1_+_185454803 20.379 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr7_-_97417730 19.021 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr11_+_78322965 18.051 ENSMUST00000017534.8
Aldoc
aldolase C, fructose-bisphosphate
chr3_+_94933041 17.942 ENSMUST00000090839.5
Selenbp1
selenium binding protein 1
chr7_+_130936172 17.936 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr7_-_79386943 16.440 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr11_-_116110211 15.965 ENSMUST00000106441.1
ENSMUST00000021120.5
Trim47

tripartite motif-containing 47

chr3_+_94693556 14.964 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
Selenbp2



selenium binding protein 2



chr2_+_31470207 14.856 ENSMUST00000102840.4
Ass1
argininosuccinate synthetase 1
chrX_+_166238901 14.665 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chr11_-_102897123 14.641 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr19_-_42752710 14.379 ENSMUST00000076505.3
Pyroxd2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr10_+_57784914 14.243 ENSMUST00000165013.1
Fabp7
fatty acid binding protein 7, brain
chr18_-_78123324 14.045 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr2_-_125723387 13.802 ENSMUST00000042246.7
Shc4
SHC (Src homology 2 domain containing) family, member 4
chr11_-_110095937 13.530 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr1_+_172341197 13.508 ENSMUST00000056136.3
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chrX_+_166238923 13.056 ENSMUST00000060210.7
ENSMUST00000112233.1
Gpm6b

glycoprotein m6b

chr11_+_3989924 12.964 ENSMUST00000109981.1
Gal3st1
galactose-3-O-sulfotransferase 1
chr5_-_9725305 12.762 ENSMUST00000004076.3
Grm3
glutamate receptor, metabotropic 3
chr3_+_57736056 12.666 ENSMUST00000041826.9
Rnf13
ring finger protein 13
chr14_+_65970610 12.623 ENSMUST00000127387.1
Clu
clusterin
chr14_+_65971049 12.118 ENSMUST00000128539.1
Clu
clusterin
chr18_-_80986578 11.995 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr14_+_65970804 11.727 ENSMUST00000138191.1
Clu
clusterin
chr8_+_22757744 11.450 ENSMUST00000033941.5
Plat
plasminogen activator, tissue
chr14_+_65971164 11.325 ENSMUST00000144619.1
Clu
clusterin
chr11_-_102897146 11.239 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr5_-_77115145 10.836 ENSMUST00000081964.5
Hopx
HOP homeobox
chr7_-_105482197 10.787 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr7_+_35186370 10.607 ENSMUST00000135452.1
ENSMUST00000001854.5
Slc7a10

solute carrier family 7 (cationic amino acid transporter, y+ system), member 10

chr11_-_109722214 10.423 ENSMUST00000020938.7
Fam20a
family with sequence similarity 20, member A
chr6_-_24956106 10.256 ENSMUST00000127247.2
Tmem229a
transmembrane protein 229A
chr2_+_102658640 10.038 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr6_+_29433248 9.876 ENSMUST00000101617.2
ENSMUST00000065090.5
Flnc

filamin C, gamma

chr18_-_78206408 9.829 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr17_-_32947372 9.495 ENSMUST00000139353.1
Cyp4f13
cytochrome P450, family 4, subfamily f, polypeptide 13
chr4_+_130047914 9.202 ENSMUST00000142293.1
Col16a1
collagen, type XVI, alpha 1
chr6_+_120773633 9.103 ENSMUST00000112682.2
Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr5_+_16553488 8.983 ENSMUST00000030683.3
Hgf
hepatocyte growth factor
chr17_+_8340710 8.901 ENSMUST00000163887.1
Prr18
proline rich region 18
chr3_-_73056943 8.834 ENSMUST00000059407.7
Slitrk3
SLIT and NTRK-like family, member 3
chr5_-_134747241 8.621 ENSMUST00000015138.9
Eln
elastin
chr5_+_137758133 8.515 ENSMUST00000141733.1
ENSMUST00000110985.1
Tsc22d4

TSC22 domain family, member 4

chr5_-_38480131 8.113 ENSMUST00000143758.1
ENSMUST00000067886.5
Slc2a9

solute carrier family 2 (facilitated glucose transporter), member 9

chr10_+_40629987 7.556 ENSMUST00000019977.7
Ddo
D-aspartate oxidase
chr12_+_95692212 7.548 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr2_+_129592818 7.533 ENSMUST00000153491.1
ENSMUST00000161620.1
ENSMUST00000179001.1
Sirpa


signal-regulatory protein alpha


chr18_+_37806389 7.460 ENSMUST00000076807.4
Pcdhga9
protocadherin gamma subfamily A, 9
chr6_+_17306415 7.272 ENSMUST00000150901.1
Cav1
caveolin 1, caveolae protein
chr19_+_4594312 7.075 ENSMUST00000113825.2
Pcx
pyruvate carboxylase
chr11_+_109485606 7.050 ENSMUST00000106697.1
Arsg
arylsulfatase G
chr9_+_69453620 6.832 ENSMUST00000034756.8
ENSMUST00000123470.1
Anxa2

annexin A2

chr2_+_129592914 6.827 ENSMUST00000103203.1
Sirpa
signal-regulatory protein alpha
chr6_+_29433131 6.796 ENSMUST00000090474.4
Flnc
filamin C, gamma
chr4_-_93335510 6.773 ENSMUST00000066774.4
Tusc1
tumor suppressor candidate 1
chr5_-_150594493 6.761 ENSMUST00000016279.7
N4bp2l1
NEDD4 binding protein 2-like 1
chr3_-_116129615 6.698 ENSMUST00000029574.8
Vcam1
vascular cell adhesion molecule 1
chr17_+_24470393 6.695 ENSMUST00000053024.6
Pgp
phosphoglycolate phosphatase
chr14_+_54259227 6.566 ENSMUST00000041197.7
Abhd4
abhydrolase domain containing 4
chr2_+_152754156 6.533 ENSMUST00000010020.5
Cox4i2
cytochrome c oxidase subunit IV isoform 2
chr1_-_120120138 6.272 ENSMUST00000112648.1
ENSMUST00000128408.1
Dbi

diazepam binding inhibitor

chr1_-_5019342 6.231 ENSMUST00000002533.8
Rgs20
regulator of G-protein signaling 20
chr9_+_69454066 6.229 ENSMUST00000134907.1
Anxa2
annexin A2
chr11_+_115154139 5.999 ENSMUST00000021076.5
Rab37
RAB37, member of RAS oncogene family
chr17_-_32947389 5.936 ENSMUST00000075253.6
Cyp4f13
cytochrome P450, family 4, subfamily f, polypeptide 13
chr19_+_32619997 5.906 ENSMUST00000025833.6
Papss2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr13_+_74639866 5.836 ENSMUST00000169114.1
Erap1
endoplasmic reticulum aminopeptidase 1
chr9_-_79718631 5.751 ENSMUST00000180083.1
Col12a1
collagen, type XII, alpha 1
chr17_+_32685655 5.541 ENSMUST00000008801.6
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr3_-_63964768 5.440 ENSMUST00000029402.8
Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr7_-_80403315 5.420 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr7_+_27447978 5.384 ENSMUST00000037399.9
ENSMUST00000108358.1
Blvrb

biliverdin reductase B (flavin reductase (NADPH))

chr1_-_87573825 5.345 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr9_-_54661870 5.339 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr17_+_34203527 5.333 ENSMUST00000025197.5
Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr3_-_63964659 5.318 ENSMUST00000161659.1
Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr11_-_77894096 5.258 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr5_+_137745967 5.244 ENSMUST00000100539.3
Tsc22d4
TSC22 domain family, member 4
chr15_+_74563738 5.238 ENSMUST00000170845.1
Bai1
brain-specific angiogenesis inhibitor 1
chr7_-_134232005 5.230 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr1_+_51289106 5.121 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr12_+_73997749 5.104 ENSMUST00000110451.2
Syt16
synaptotagmin XVI
chr14_+_70530819 5.095 ENSMUST00000047331.6
Lgi3
leucine-rich repeat LGI family, member 3
chr7_+_47050628 5.059 ENSMUST00000010451.5
Tmem86a
transmembrane protein 86A
chr7_+_30553263 4.921 ENSMUST00000044048.7
Hspb6
heat shock protein, alpha-crystallin-related, B6
chr12_-_80132802 4.908 ENSMUST00000180643.1
2310015A10Rik
RIKEN cDNA 2310015A10 gene
chr3_-_57294880 4.904 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr3_-_107760221 4.891 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr4_+_41762309 4.780 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr2_-_29253001 4.760 ENSMUST00000071201.4
Ntng2
netrin G2
chr9_-_79718518 4.742 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr3_+_54755574 4.662 ENSMUST00000029371.2
Smad9
SMAD family member 9
chr11_-_110095974 4.635 ENSMUST00000100287.2
Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr4_+_45965327 4.597 ENSMUST00000107777.2
Tdrd7
tudor domain containing 7
chr17_+_71673255 4.572 ENSMUST00000097284.3
Fam179a
family with sequence similarity 179, member A
chr18_+_69593361 4.518 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr8_-_67818284 4.499 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr2_+_165503787 4.490 ENSMUST00000029196.4
Slc2a10
solute carrier family 2 (facilitated glucose transporter), member 10
chr19_-_3929723 4.464 ENSMUST00000051803.6
Aldh3b1
aldehyde dehydrogenase 3 family, member B1
chr6_+_54681687 4.432 ENSMUST00000046276.6
2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr11_+_61485431 4.298 ENSMUST00000064783.3
ENSMUST00000040522.6
Mfap4

microfibrillar-associated protein 4

chr9_-_79718720 4.268 ENSMUST00000121227.1
Col12a1
collagen, type XII, alpha 1
chr8_-_123894736 4.211 ENSMUST00000034453.4
Acta1
actin, alpha 1, skeletal muscle
chr8_-_64693027 4.188 ENSMUST00000048967.7
Cpe
carboxypeptidase E
chr11_-_61579637 4.151 ENSMUST00000147501.1
ENSMUST00000146455.1
ENSMUST00000108711.1
ENSMUST00000108712.1
ENSMUST00000001063.8
ENSMUST00000108713.1
ENSMUST00000179936.1
ENSMUST00000178202.1
Epn2







epsin 2







chr3_+_52268337 4.147 ENSMUST00000053764.5
Foxo1
forkhead box O1
chr10_+_96136603 4.138 ENSMUST00000074615.6
Gm5426
predicted pseudogene 5426
chr13_-_98815408 4.033 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
Fcho2



FCH domain only 2



chr3_-_146812951 3.986 ENSMUST00000102515.3
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr16_+_91406235 3.985 ENSMUST00000023691.5
Il10rb
interleukin 10 receptor, beta
chr19_-_6840590 3.860 ENSMUST00000170516.2
ENSMUST00000025903.5
Rps6ka4

ribosomal protein S6 kinase, polypeptide 4

chr7_-_134232125 3.843 ENSMUST00000127524.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr2_-_26122769 3.831 ENSMUST00000140993.1
ENSMUST00000028300.5
Nacc2

nucleus accumbens associated 2, BEN and BTB (POZ) domain containing

chr5_-_84417359 3.831 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr13_-_97747373 3.645 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr15_+_54745702 3.633 ENSMUST00000050027.8
Nov
nephroblastoma overexpressed gene
chr14_-_122451109 3.512 ENSMUST00000081580.2
Gm5089
predicted gene 5089
chr7_+_45017953 3.482 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr18_+_82554463 3.450 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp










myelin basic protein










chr2_-_180225812 3.426 ENSMUST00000015791.5
Lama5
laminin, alpha 5
chr2_+_129593195 3.360 ENSMUST00000099113.3
ENSMUST00000103202.3
Sirpa

signal-regulatory protein alpha

chr2_+_32646586 3.349 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng

endoglin

chr14_-_62454793 3.343 ENSMUST00000128573.1
Gucy1b2
guanylate cyclase 1, soluble, beta 2
chr14_+_62332068 3.320 ENSMUST00000022499.6
Rnaseh2b
ribonuclease H2, subunit B
chr2_-_93849679 3.317 ENSMUST00000068513.4
ENSMUST00000041593.8
ENSMUST00000130077.1
Accs


1-aminocyclopropane-1-carboxylate synthase (non-functional)


chr10_-_105574435 3.314 ENSMUST00000061506.8
Tmtc2
transmembrane and tetratricopeptide repeat containing 2
chr6_+_138141569 3.311 ENSMUST00000118091.1
Mgst1
microsomal glutathione S-transferase 1
chr5_-_110286159 3.240 ENSMUST00000031472.5
Pxmp2
peroxisomal membrane protein 2
chr5_+_9266097 3.205 ENSMUST00000134991.1
ENSMUST00000069538.7
ENSMUST00000115348.2
9330182L06Rik


RIKEN cDNA 9330182L06 gene


chr1_-_131527302 3.071 ENSMUST00000097588.2
Srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr15_+_40655020 3.023 ENSMUST00000053467.4
Zfpm2
zinc finger protein, multitype 2
chr6_-_73221625 3.012 ENSMUST00000064948.6
ENSMUST00000114040.1
Dnah6

dynein, axonemal, heavy chain 6

chr15_+_102102926 3.009 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1

tensin like C1 domain-containing phosphatase

chr7_+_27607997 2.982 ENSMUST00000142365.1
Akt2
thymoma viral proto-oncogene 2
chr9_+_88327592 2.976 ENSMUST00000034992.6
Nt5e
5' nucleotidase, ecto
chr5_+_137745730 2.974 ENSMUST00000100540.3
Tsc22d4
TSC22 domain family, member 4
chr11_+_78178651 2.940 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
Tlcd1


TLC domain containing 1


chr1_+_174501796 2.927 ENSMUST00000030039.7
Fmn2
formin 2
chr9_-_71163224 2.885 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr5_-_135078224 2.879 ENSMUST00000067935.4
ENSMUST00000076203.2
Vps37d

vacuolar protein sorting 37D (yeast)

chr10_+_70245083 2.830 ENSMUST00000046807.6
Slc16a9
solute carrier family 16 (monocarboxylic acid transporters), member 9
chr3_+_122245557 2.722 ENSMUST00000029769.7
Gclm
glutamate-cysteine ligase, modifier subunit
chr5_+_64812336 2.666 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr1_+_92910758 2.647 ENSMUST00000027487.8
Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr6_+_83034173 2.629 ENSMUST00000000707.2
ENSMUST00000101257.3
Loxl3

lysyl oxidase-like 3

chr6_-_48841098 2.621 ENSMUST00000101429.4
Tmem176b
transmembrane protein 176B
chr14_+_54426902 2.568 ENSMUST00000010550.7
Mrpl52
mitochondrial ribosomal protein L52
chr8_-_111910171 2.543 ENSMUST00000034430.4
Chst5
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr17_-_33713372 2.512 ENSMUST00000173392.1
March2
membrane-associated ring finger (C3HC4) 2
chr1_-_133801031 2.463 ENSMUST00000143567.1
Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
chr7_-_142578139 2.454 ENSMUST00000136359.1
H19
H19 fetal liver mRNA
chr6_-_48840988 2.446 ENSMUST00000164733.1
Tmem176b
transmembrane protein 176B
chr15_-_98296083 2.434 ENSMUST00000169721.1
ENSMUST00000023722.5
Zfp641

zinc finger protein 641

chr3_-_65529355 2.430 ENSMUST00000099076.3
4931440P22Rik
RIKEN cDNA 4931440P22 gene
chr5_-_34513892 2.417 ENSMUST00000114359.1
ENSMUST00000030991.7
ENSMUST00000087737.3
Tnip2


TNFAIP3 interacting protein 2


chr3_+_135826075 2.404 ENSMUST00000029810.5
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr8_-_86580664 2.402 ENSMUST00000131423.1
ENSMUST00000152438.1
Abcc12

ATP-binding cassette, sub-family C (CFTR/MRP), member 12

chr2_+_27079371 2.382 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chr9_-_15301555 2.358 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr5_+_31048627 2.353 ENSMUST00000013766.6
ENSMUST00000173215.1
ENSMUST00000153643.1
ENSMUST00000114659.2
Atraid



all-trans retinoic acid induced differentiation factor



chr14_+_62292475 2.299 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr7_-_142578093 2.283 ENSMUST00000149974.1
ENSMUST00000152754.1
H19

H19 fetal liver mRNA

chr7_+_27607748 2.271 ENSMUST00000136962.1
Akt2
thymoma viral proto-oncogene 2
chr10_+_59879617 2.256 ENSMUST00000142819.1
ENSMUST00000020309.6
Dnajb12

DnaJ (Hsp40) homolog, subfamily B, member 12

chr3_+_146220955 2.256 ENSMUST00000039164.2
Lpar3
lysophosphatidic acid receptor 3
chr2_+_120629113 2.194 ENSMUST00000150912.1
ENSMUST00000180041.1
Stard9

START domain containing 9

chr10_-_78351711 2.155 ENSMUST00000105390.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr4_+_141239499 2.119 ENSMUST00000141834.2
Arhgef19
Rho guanine nucleotide exchange factor (GEF) 19
chr4_-_147848358 2.111 ENSMUST00000105718.1
ENSMUST00000135798.1
Zfp933

zinc finger protein 933

chr4_-_9643638 2.075 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
Asph




aspartate-beta-hydroxylase




chr4_+_152338887 2.012 ENSMUST00000005175.4
Chd5
chromodomain helicase DNA binding protein 5
chr6_-_118780324 2.007 ENSMUST00000112793.3
ENSMUST00000075591.6
ENSMUST00000078320.7
ENSMUST00000112790.2
Cacna1c



calcium channel, voltage-dependent, L type, alpha 1C subunit



chr10_-_78351690 2.005 ENSMUST00000166360.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr5_-_38491948 2.005 ENSMUST00000129099.1
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr3_+_135825648 2.000 ENSMUST00000180196.1
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr12_-_69893162 1.997 ENSMUST00000049239.7
ENSMUST00000110570.1
Map4k5

mitogen-activated protein kinase kinase kinase kinase 5

chr7_-_142576492 1.968 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr8_-_69902712 1.945 ENSMUST00000180068.1
Yjefn3
YjeF N-terminal domain containing 3
chr5_-_116288978 1.943 ENSMUST00000050178.6
Ccdc60
coiled-coil domain containing 60
chr17_+_28272191 1.933 ENSMUST00000169040.1
Ppard
peroxisome proliferator activator receptor delta
chr3_-_89245159 1.925 ENSMUST00000090924.6
Trim46
tripartite motif-containing 46
chr9_-_119977250 1.925 ENSMUST00000035101.7
Csrnp1
cysteine-serine-rich nuclear protein 1
chr4_+_139622842 1.895 ENSMUST00000039818.9
Aldh4a1
aldehyde dehydrogenase 4 family, member A1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
12.3 61.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
12.1 60.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
8.0 47.8 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
6.0 29.9 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
5.9 59.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
5.9 47.0 GO:0070314 G1 to G0 transition(GO:0070314)
5.9 23.5 GO:0019372 lipoxygenase pathway(GO:0019372)
4.5 13.5 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
4.3 13.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
4.3 25.9 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
4.0 27.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
3.8 26.8 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
3.7 14.9 GO:0010046 arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046)
3.6 10.8 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
3.3 6.7 GO:0019401 alditol biosynthetic process(GO:0019401)
3.2 12.8 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
3.1 18.5 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
3.0 17.9 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
2.5 7.6 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid catabolic process(GO:0019478)
2.4 24.0 GO:0009404 toxin metabolic process(GO:0009404)
2.4 7.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
2.3 20.6 GO:0042940 D-amino acid transport(GO:0042940)
2.3 20.4 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
2.1 37.6 GO:0060134 prepulse inhibition(GO:0060134)
2.1 10.4 GO:0070166 enamel mineralization(GO:0070166)
2.0 5.9 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035)
1.8 3.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
1.8 9.0 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
1.8 5.3 GO:0006553 lysine metabolic process(GO:0006553)
1.7 15.4 GO:0006691 leukotriene metabolic process(GO:0006691)
1.6 4.9 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
1.4 4.2 GO:0030070 insulin processing(GO:0030070)
1.3 5.3 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
1.3 12.9 GO:0046415 urate metabolic process(GO:0046415)
1.3 23.2 GO:0032060 bleb assembly(GO:0032060)
1.3 3.9 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
1.3 7.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
1.3 6.3 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
1.2 2.5 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
1.1 11.4 GO:0031639 plasminogen activation(GO:0031639)
1.1 29.5 GO:0033622 integrin activation(GO:0033622)
1.1 3.3 GO:0003032 detection of oxygen(GO:0003032)
1.1 5.4 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.0 3.0 GO:0003195 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.0 4.0 GO:0044565 dendritic cell proliferation(GO:0044565)
1.0 2.9 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
1.0 6.7 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.9 5.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.8 4.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.8 3.3 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.8 2.4 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.8 2.4 GO:2000598 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.7 12.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.7 4.5 GO:0035428 hexose transmembrane transport(GO:0035428)
0.7 17.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.7 5.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.7 20.2 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.7 2.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.7 4.1 GO:0071455 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093) cellular response to hyperoxia(GO:0071455)
0.7 4.7 GO:0001880 Mullerian duct regression(GO:0001880)
0.7 1.3 GO:0006566 threonine metabolic process(GO:0006566)
0.6 6.7 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.6 6.7 GO:0061032 visceral serous pericardium development(GO:0061032)
0.6 5.8 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.5 26.6 GO:0048678 response to axon injury(GO:0048678)
0.5 3.1 GO:0021814 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814)
0.5 2.0 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.5 2.0 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.5 3.0 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.5 4.3 GO:0071493 elastic fiber assembly(GO:0048251) cellular response to UV-B(GO:0071493)
0.5 5.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.5 4.2 GO:0051409 response to nitrosative stress(GO:0051409)
0.5 1.4 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.5 4.5 GO:0042118 endothelial cell activation(GO:0042118)
0.4 5.3 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.4 1.7 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.4 8.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.4 1.2 GO:0019085 early viral transcription(GO:0019085)
0.4 4.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.4 1.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.4 1.2 GO:0070488 neutrophil aggregation(GO:0070488)
0.4 3.8 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.4 4.8 GO:0046697 decidualization(GO:0046697)
0.4 12.8 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.4 1.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.3 1.9 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.3 1.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.3 9.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.3 5.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.3 4.6 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.3 1.6 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.3 1.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 3.8 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.2 14.8 GO:0048747 muscle fiber development(GO:0048747)
0.2 0.9 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.2 0.4 GO:0010872 regulation of cholesterol esterification(GO:0010872)
0.2 4.5 GO:0046185 aldehyde catabolic process(GO:0046185)
0.2 7.8 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.2 1.3 GO:0014745 negative regulation of muscle adaptation(GO:0014745)
0.2 1.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 3.3 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.2 12.7 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 4.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 7.2 GO:0019915 lipid storage(GO:0019915)
0.2 4.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.2 1.9 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.2 1.0 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2 9.2 GO:0006970 response to osmotic stress(GO:0006970)
0.2 5.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.2 0.9 GO:0097186 amelogenesis(GO:0097186)
0.2 3.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.6 GO:0006570 tyrosine metabolic process(GO:0006570) ventricular zone neuroblast division(GO:0021847)
0.1 11.9 GO:0007601 visual perception(GO:0007601)
0.1 2.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 1.7 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.7 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 1.3 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 1.8 GO:0010388 cullin deneddylation(GO:0010388)
0.1 0.7 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.1 0.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.8 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 2.6 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.7 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.3 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 1.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 1.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 2.7 GO:0060325 face morphogenesis(GO:0060325)
0.1 1.4 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 3.4 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 3.0 GO:0003341 cilium movement(GO:0003341)
0.1 0.4 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 1.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 1.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.3 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 0.4 GO:0001975 response to amphetamine(GO:0001975) response to amine(GO:0014075)
0.0 0.6 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 3.4 GO:0042552 myelination(GO:0042552)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 3.6 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.4 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0019336 phenol-containing compound catabolic process(GO:0019336) hormone catabolic process(GO:0042447)
0.0 0.9 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.5 GO:0021681 cerebellar granular layer development(GO:0021681)
0.0 0.6 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 2.2 GO:0051225 spindle assembly(GO:0051225)
0.0 0.0 GO:0072008 glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.0 2.8 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 1.0 GO:0016064 immunoglobulin mediated immune response(GO:0016064)
0.0 0.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 2.9 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.7 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.2 GO:0006206 pyrimidine nucleobase metabolic process(GO:0006206)
0.0 3.7 GO:0048863 stem cell differentiation(GO:0048863)
0.0 0.8 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 47.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
6.5 25.9 GO:0097450 astrocyte end-foot(GO:0097450)
4.9 14.8 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
4.4 13.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
4.3 12.9 GO:0071953 elastic fiber(GO:0071953)
2.9 26.3 GO:0097449 astrocyte projection(GO:0097449)
2.0 29.9 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.6 4.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.4 4.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
1.0 3.0 GO:0036156 inner dynein arm(GO:0036156)
1.0 12.8 GO:0070852 cell body fiber(GO:0070852)
0.9 5.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.9 3.4 GO:0043259 laminin-10 complex(GO:0043259)
0.8 5.3 GO:0042825 TAP complex(GO:0042825)
0.7 56.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.7 5.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.7 4.6 GO:0033391 chromatoid body(GO:0033391)
0.5 5.4 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.4 4.5 GO:0044327 dendritic spine head(GO:0044327)
0.4 3.4 GO:0033269 internode region of axon(GO:0033269)
0.4 2.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.4 5.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.4 16.4 GO:0044297 cell body(GO:0044297)
0.4 3.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.4 1.8 GO:0030314 junctional membrane complex(GO:0030314)
0.3 10.6 GO:0097440 apical dendrite(GO:0097440)
0.3 10.0 GO:0030673 axolemma(GO:0030673)
0.3 2.9 GO:0000813 ESCRT I complex(GO:0000813)
0.3 1.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.3 12.4 GO:0031902 late endosome membrane(GO:0031902)
0.3 5.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.3 4.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 4.2 GO:0031045 dense core granule(GO:0031045)
0.3 6.7 GO:0002102 podosome(GO:0002102)
0.2 5.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 19.2 GO:0097060 synaptic membrane(GO:0097060)
0.2 15.8 GO:0005581 collagen trimer(GO:0005581)
0.2 5.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 17.0 GO:0005604 basement membrane(GO:0005604)
0.2 22.0 GO:0005814 centriole(GO:0005814)
0.2 0.6 GO:1990879 CST complex(GO:1990879)
0.2 37.3 GO:0030017 sarcomere(GO:0030017)
0.2 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 6.3 GO:0043292 contractile fiber(GO:0043292)
0.2 13.6 GO:0005901 caveola(GO:0005901)
0.1 26.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 6.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 3.6 GO:0005921 gap junction(GO:0005921)
0.1 14.2 GO:0042383 sarcolemma(GO:0042383)
0.1 6.7 GO:0005844 polysome(GO:0005844)
0.1 5.2 GO:0005811 lipid particle(GO:0005811)
0.1 0.6 GO:0070847 core mediator complex(GO:0070847)
0.1 1.7 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 5.2 GO:0031012 extracellular matrix(GO:0031012)
0.1 1.0 GO:0001527 microfibril(GO:0001527)
0.1 11.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 4.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 40.2 GO:0030424 axon(GO:0030424)
0.1 4.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 25.8 GO:0043025 neuronal cell body(GO:0043025)
0.1 47.5 GO:0005615 extracellular space(GO:0005615)
0.1 22.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 0.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 1.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.9 GO:0005884 actin filament(GO:0005884)
0.0 2.9 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.3 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 115.8 GO:0016021 integral component of membrane(GO:0016021)
0.0 2.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 1.8 GO:0005938 cell cortex(GO:0005938)
0.0 0.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
15.4 61.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
10.2 61.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
6.0 29.9 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
4.8 24.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
4.6 60.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
4.5 13.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
4.5 26.8 GO:0015265 urea channel activity(GO:0015265)
3.6 10.8 GO:0008521 acetyl-CoA transporter activity(GO:0008521)
3.4 10.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
3.3 13.1 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
3.0 12.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
2.7 16.4 GO:0019841 retinol binding(GO:0019841)
2.6 12.8 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
2.5 10.2 GO:0003884 D-amino-acid oxidase activity(GO:0003884) aspartate oxidase activity(GO:0015922)
2.5 10.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
2.3 2.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
2.2 6.7 GO:0008131 primary amine oxidase activity(GO:0008131)
2.1 47.8 GO:0051787 misfolded protein binding(GO:0051787)
2.1 30.8 GO:0008430 selenium binding(GO:0008430)
1.7 6.7 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
1.7 14.9 GO:0015643 toxic substance binding(GO:0015643)
1.6 6.3 GO:0030156 benzodiazepine receptor binding(GO:0030156)
1.4 4.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
1.3 5.4 GO:0004074 biliverdin reductase activity(GO:0004074)
1.3 5.3 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
1.3 5.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
1.3 3.9 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
1.2 4.8 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
1.2 7.1 GO:0009374 biotin binding(GO:0009374)
1.1 4.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.1 3.3 GO:0005534 galactose binding(GO:0005534)
1.0 38.7 GO:0005504 fatty acid binding(GO:0005504)
0.9 24.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.9 4.5 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.9 7.0 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.9 3.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.9 18.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.8 10.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.7 5.9 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
0.7 5.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.7 16.7 GO:0030506 ankyrin binding(GO:0030506)
0.7 4.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.7 4.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.6 1.3 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.6 5.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.6 2.4 GO:0050436 microfibril binding(GO:0050436)
0.5 56.8 GO:0005178 integrin binding(GO:0005178)
0.5 3.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.5 1.4 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.4 1.3 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.4 17.7 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.4 8.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.4 2.0 GO:0086056 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.4 7.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.4 5.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.4 4.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.4 1.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 4.5 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.4 3.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.4 7.8 GO:0042056 chemoattractant activity(GO:0042056)
0.4 9.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.4 1.8 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.3 4.2 GO:0050897 cobalt ion binding(GO:0050897)
0.3 13.0 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.3 1.7 GO:0001849 complement component C1q binding(GO:0001849)
0.3 1.0 GO:0030172 troponin C binding(GO:0030172)
0.3 1.7 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.3 0.8 GO:0030957 Tat protein binding(GO:0030957)
0.3 1.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.3 8.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 1.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 0.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 1.7 GO:0001515 opioid peptide activity(GO:0001515)
0.2 5.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 3.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 22.2 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.2 5.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 9.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.2 0.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 11.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.2 6.6 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.2 3.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171)
0.2 5.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 2.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 3.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 9.3 GO:0005080 protein kinase C binding(GO:0005080)
0.1 3.0 GO:0008198 ferrous iron binding(GO:0008198)
0.1 0.4 GO:0050827 toxin receptor binding(GO:0050827)
0.1 1.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 3.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 2.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 2.5 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.1 2.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 1.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 10.5 GO:0015293 symporter activity(GO:0015293)
0.1 0.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 4.4 GO:0003777 microtubule motor activity(GO:0003777)
0.1 3.3 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 8.7 GO:0017124 SH3 domain binding(GO:0017124)
0.1 11.6 GO:0030246 carbohydrate binding(GO:0030246)
0.1 2.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.2 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.6 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 1.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0 1.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.7 GO:0016746 transferase activity, transferring acyl groups(GO:0016746)
0.0 2.1 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 9.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.8 GO:0020037 heme binding(GO:0020037)
0.0 4.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.5 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.8 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.9 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.3 GO:0004497 monooxygenase activity(GO:0004497)