Motif ID: Nfix

Z-value: 1.589


Transcription factors associated with Nfix:

Gene SymbolEntrez IDGene Name
Nfix ENSMUSG00000001911.10 Nfix

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfixmm10_v2_chr8_-_84773381_847734270.721.8e-10Click!


Activity profile for motif Nfix.

activity profile for motif Nfix


Sorted Z-values histogram for motif Nfix

Sorted Z-values for motif Nfix



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfix

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_141524379 48.929 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr7_-_97417730 28.444 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr10_+_57784859 25.095 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr10_+_57784914 22.169 ENSMUST00000165013.1
Fabp7
fatty acid binding protein 7, brain
chr11_+_3488275 18.136 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr11_-_102897123 16.746 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr7_+_130936172 15.018 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr16_+_42907563 13.685 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr18_-_78123324 13.320 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr18_-_23038656 12.451 ENSMUST00000081423.6
Nol4
nucleolar protein 4
chr5_+_66745835 12.409 ENSMUST00000101164.4
ENSMUST00000118242.1
ENSMUST00000119854.1
ENSMUST00000117601.1
Limch1



LIM and calponin homology domains 1



chr11_+_63128973 12.172 ENSMUST00000108702.1
Pmp22
peripheral myelin protein 22
chr1_+_169929929 11.937 ENSMUST00000175731.1
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr11_-_102897146 11.832 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr6_+_135362931 11.493 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr7_-_103827922 11.407 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr1_-_172219715 11.237 ENSMUST00000170700.1
ENSMUST00000003554.4
Casq1

calsequestrin 1

chr17_-_49564262 11.153 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr5_-_77115145 9.566 ENSMUST00000081964.5
Hopx
HOP homeobox
chr4_-_148287927 9.087 ENSMUST00000047720.8
Ptchd2
patched domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 114 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.9 48.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
2.6 47.3 GO:0060134 prepulse inhibition(GO:0060134)
1.1 30.7 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
4.8 28.6 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
1.3 23.7 GO:0032060 bleb assembly(GO:0032060)
4.5 18.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.5 16.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 16.5 GO:0031032 actomyosin structure organization(GO:0031032)
1.1 15.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
2.5 15.0 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
2.2 13.3 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
1.1 13.1 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
2.5 12.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.9 11.6 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
3.7 11.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.6 11.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.7 10.1 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
1.6 9.6 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 8.9 GO:0007605 sensory perception of sound(GO:0007605)
0.2 8.8 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 72.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 59.8 GO:0005911 cell-cell junction(GO:0005911)
0.1 30.2 GO:0031012 extracellular matrix(GO:0031012)
7.1 28.6 GO:0097450 astrocyte end-foot(GO:0097450)
0.2 26.0 GO:0031225 anchored component of membrane(GO:0031225)
0.2 19.0 GO:0005814 centriole(GO:0005814)
0.2 17.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.5 12.2 GO:0043218 compact myelin(GO:0043218)
0.5 11.6 GO:0000930 gamma-tubulin complex(GO:0000930)
2.9 11.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
3.7 11.2 GO:0014802 terminal cisterna(GO:0014802)
0.1 9.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 9.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
1.7 8.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 7.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.4 7.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 6.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 6.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 6.4 GO:0032420 stereocilium(GO:0032420)
0.0 5.9 GO:0005813 centrosome(GO:0005813)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 86 entries
Log-likelihood per target Total log-likelihoodTermDescription
12.2 48.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.1 44.5 GO:0005504 fatty acid binding(GO:0005504)
0.3 26.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 16.9 GO:0008270 zinc ion binding(GO:0008270)
0.4 15.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.7 15.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 13.7 GO:0005509 calcium ion binding(GO:0005509)
0.1 13.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
2.2 13.3 GO:0015265 urea channel activity(GO:0015265)
1.0 12.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 11.6 GO:0043015 gamma-tubulin binding(GO:0043015)
2.9 11.4 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
1.8 11.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.7 10.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 10.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 10.1 GO:0008565 protein transporter activity(GO:0008565)
0.1 9.7 GO:0017048 Rho GTPase binding(GO:0017048)
2.9 8.8 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
1.4 8.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 8.6 GO:0003735 structural constituent of ribosome(GO:0003735)