Motif ID: Nhlh1

Z-value: 1.254


Transcription factors associated with Nhlh1:

Gene SymbolEntrez IDGene Name
Nhlh1 ENSMUSG00000051251.3 Nhlh1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nhlh1mm10_v2_chr1_-_172057573_172057598-0.133.3e-01Click!


Activity profile for motif Nhlh1.

activity profile for motif Nhlh1


Sorted Z-values histogram for motif Nhlh1

Sorted Z-values for motif Nhlh1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nhlh1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_64046925 16.769 ENSMUST00000107377.3
 Tnc
tenascin C
chr16_+_91269759 15.366 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr4_-_120287349 10.718 ENSMUST00000102656.3
 Foxo6
forkhead box O6
chr3_-_84304762 8.921 ENSMUST00000107692.1
 Trim2
tripartite motif-containing 2
chr7_+_130936172 8.841 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr10_-_27616895 8.293 ENSMUST00000092639.5
 Lama2
laminin, alpha 2
chr2_+_25395866 8.103 ENSMUST00000028328.2
 Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr4_+_104367549 7.911 ENSMUST00000106830.2
 Dab1
disabled 1
chr2_+_70562007 7.360 ENSMUST00000094934.4
 Gad1
glutamate decarboxylase 1
chr7_+_122289297 6.869 ENSMUST00000064989.5
ENSMUST00000064921.4
 Prkcb

protein kinase C, beta

chr10_+_3366125 6.493 ENSMUST00000043374.5
 Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr19_-_5457397 6.485 ENSMUST00000179549.1
 Ccdc85b
coiled-coil domain containing 85B
chr15_+_81811414 6.365 ENSMUST00000023024.7
 Tef
thyrotroph embryonic factor
chr2_+_102658640 6.352 ENSMUST00000080210.3
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr13_-_32802849 6.107 ENSMUST00000057911.1
 D930007J09Rik
RIKEN cDNA D930007J09 gene
chr7_+_46396439 6.005 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr15_+_81936753 5.622 ENSMUST00000038757.7
 Csdc2
cold shock domain containing C2, RNA binding
chr1_-_84696182 5.604 ENSMUST00000049126.6
 Dner
delta/notch-like EGF-related receptor
chr1_+_86045863 5.572 ENSMUST00000165824.1
 2810459M11Rik
RIKEN cDNA 2810459M11 gene
chr11_+_113619318 5.513 ENSMUST00000146390.2
ENSMUST00000106630.1
 Sstr2

somatostatin receptor 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 445 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 16.4 GO:0048709 oligodendrocyte differentiation(GO:0048709)
4.0 16.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.9 13.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 12.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.3 11.2 GO:0060074 synapse maturation(GO:0060074)
0.2 10.7 GO:0030517 negative regulation of axon extension(GO:0030517)
1.3 9.2 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
1.8 8.9 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
1.5 8.8 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.4 8.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.0 8.0 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
2.4 7.2 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
2.4 7.1 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
1.2 7.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 7.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 6.8 GO:0014037 Schwann cell differentiation(GO:0014037)
1.3 6.4 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 6.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.6 6.1 GO:0009404 toxin metabolic process(GO:0009404)
0.6 6.1 GO:0036159 inner dynein arm assembly(GO:0036159)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 179 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 16.8 GO:0005614 interstitial matrix(GO:0005614)
0.1 16.0 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.5 15.8 GO:0060077 inhibitory synapse(GO:0060077)
0.7 14.7 GO:0005605 basal lamina(GO:0005605)
0.1 13.9 GO:0005802 trans-Golgi network(GO:0005802)
0.4 13.6 GO:0030673 axolemma(GO:0030673)
0.2 11.8 GO:0031594 neuromuscular junction(GO:0031594)
0.1 9.3 GO:0005769 early endosome(GO:0005769)
0.5 9.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 7.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 7.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 7.3 GO:0043198 dendritic shaft(GO:0043198)
0.5 7.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 7.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 7.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 6.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.6 6.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 6.4 GO:0030427 site of polarized growth(GO:0030427)
0.0 6.1 GO:0000776 kinetochore(GO:0000776)
0.2 6.0 GO:0031672 A band(GO:0031672)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 286 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 19.7 GO:0005096 GTPase activator activity(GO:0005096)
0.3 19.0 GO:0017022 myosin binding(GO:0017022)
2.6 15.5 GO:0045545 syndecan binding(GO:0045545)
1.9 13.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 12.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 12.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.4 12.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 9.7 GO:0005112 Notch binding(GO:0005112)
0.7 9.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.2 8.9 GO:0042169 SH2 domain binding(GO:0042169)
0.1 8.6 GO:0051015 actin filament binding(GO:0051015)
1.4 8.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
1.0 8.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.4 7.1 GO:0018733 3,4-dihydrocoumarin hydrolase activity(GO:0018733)
0.2 7.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.5 6.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.8 6.5 GO:0035184 histone threonine kinase activity(GO:0035184)
1.6 6.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.6 6.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.6 6.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)