Motif ID: Nkx1-1_Nkx1-2

Z-value: 0.455

Transcription factors associated with Nkx1-1_Nkx1-2:

Gene SymbolEntrez IDGene Name
Nkx1-1 ENSMUSG00000029112.5 Nkx1-1
Nkx1-2 ENSMUSG00000048528.7 Nkx1-2






Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx1-1_Nkx1-2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_55782500 7.818 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr6_-_23248264 5.578 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr13_-_102905740 3.526 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr6_-_124779686 3.401 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr13_-_102906046 3.391 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr10_+_128337761 2.310 ENSMUST00000005826.7
Cs
citrate synthase
chr11_+_43682038 2.296 ENSMUST00000094294.4
Pwwp2a
PWWP domain containing 2A
chr17_-_34000257 2.212 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
H2-K1




histocompatibility 2, K1, K region




chr11_+_43681998 2.164 ENSMUST00000061070.5
Pwwp2a
PWWP domain containing 2A
chr6_+_29694204 2.079 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chrX_-_60893430 1.952 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr4_-_140774196 1.944 ENSMUST00000026381.6
Padi4
peptidyl arginine deiminase, type IV
chr14_-_52104015 1.800 ENSMUST00000111610.4
ENSMUST00000164655.1
Hnrnpc

heterogeneous nuclear ribonucleoprotein C

chr7_-_143460989 1.653 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr5_+_103425181 1.627 ENSMUST00000048957.9
Ptpn13
protein tyrosine phosphatase, non-receptor type 13
chr16_+_52031549 1.626 ENSMUST00000114471.1
Cblb
Casitas B-lineage lymphoma b
chr7_+_29983948 1.529 ENSMUST00000148442.1
Zfp568
zinc finger protein 568
chr5_+_9100681 1.460 ENSMUST00000115365.1
Tmem243
transmembrane protein 243, mitochondrial
chr3_-_116424007 1.438 ENSMUST00000090464.4
Cdc14a
CDC14 cell division cycle 14A
chr14_-_8666236 1.416 ENSMUST00000102996.3
4930452B06Rik
RIKEN cDNA 4930452B06 gene
chr5_+_138187485 1.334 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr9_-_100486788 1.325 ENSMUST00000098458.3
Il20rb
interleukin 20 receptor beta
chr4_-_132075250 1.204 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr4_-_119294520 1.177 ENSMUST00000079644.6
Ybx1
Y box protein 1
chr3_-_116423930 1.162 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chr5_+_138116903 1.082 ENSMUST00000062350.8
ENSMUST00000110961.2
ENSMUST00000080732.3
ENSMUST00000110960.2
ENSMUST00000142185.1
ENSMUST00000136425.1
ENSMUST00000110959.1
Zscan21






zinc finger and SCAN domain containing 21






chr5_+_140607334 1.074 ENSMUST00000031555.1
Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr9_-_20959785 1.025 ENSMUST00000177754.1
Dnmt1
DNA methyltransferase (cytosine-5) 1
chrX_+_106015699 0.984 ENSMUST00000033582.4
Cox7b
cytochrome c oxidase subunit VIIb
chr10_+_88147061 0.975 ENSMUST00000169309.1
Nup37
nucleoporin 37
chr11_-_87108656 0.963 ENSMUST00000051395.8
Prr11
proline rich 11
chr10_+_88146992 0.936 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr2_-_69712461 0.926 ENSMUST00000102706.3
ENSMUST00000073152.6
Fastkd1

FAST kinase domains 1

chr8_-_3694167 0.839 ENSMUST00000005678.4
Fcer2a
Fc receptor, IgE, low affinity II, alpha polypeptide
chr3_+_94372794 0.810 ENSMUST00000029795.3
Rorc
RAR-related orphan receptor gamma
chr15_+_81663889 0.806 ENSMUST00000023029.8
ENSMUST00000174229.1
ENSMUST00000172748.1
L3mbtl2


l(3)mbt-like 2 (Drosophila)


chr14_+_46760526 0.758 ENSMUST00000067426.4
Cdkn3
cyclin-dependent kinase inhibitor 3
chr2_+_110597298 0.741 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr4_-_141599835 0.734 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
Fblim1



filamin binding LIM protein 1



chr18_+_4993795 0.678 ENSMUST00000153016.1
Svil
supervillin
chr5_-_137072254 0.675 ENSMUST00000077523.3
ENSMUST00000041388.4
Serpine1

serine (or cysteine) peptidase inhibitor, clade E, member 1

chr7_+_128744870 0.644 ENSMUST00000042942.8
Sec23ip
Sec23 interacting protein
chr9_+_66126611 0.644 ENSMUST00000034945.5
Fam96a
family with sequence similarity 96, member A
chr17_-_48432723 0.642 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr3_-_34351685 0.602 ENSMUST00000174114.1
Gm20514
predicted gene 20514
chr7_+_101896340 0.598 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr11_+_87109221 0.593 ENSMUST00000020794.5
Ska2
spindle and kinetochore associated complex subunit 2
chr7_-_38019505 0.561 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chrX_-_160138375 0.531 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr11_-_99230998 0.507 ENSMUST00000103133.3
Smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr12_+_84417196 0.496 ENSMUST00000183146.1
Rnf113a2
ring finger protein 113A2
chr18_+_24603952 0.466 ENSMUST00000025120.6
Elp2
elongator acetyltransferase complex subunit 2
chr19_+_5490475 0.449 ENSMUST00000116560.2
Cfl1
cofilin 1, non-muscle
chr14_+_25980039 0.449 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr12_-_40037387 0.449 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr2_+_36230426 0.420 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr2_-_165388245 0.412 ENSMUST00000103084.3
Zfp334
zinc finger protein 334
chr9_-_44113470 0.397 ENSMUST00000056328.5
Rnf26
ring finger protein 26
chr7_+_51880312 0.379 ENSMUST00000145049.1
Gas2
growth arrest specific 2
chr10_+_116301374 0.377 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr11_-_43747963 0.375 ENSMUST00000048578.2
ENSMUST00000109278.1
Ttc1

tetratricopeptide repeat domain 1

chr19_-_41933276 0.369 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1

exosome component 1

chrX_+_107255878 0.368 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
Gpr174


G protein-coupled receptor 174


chr10_-_88146867 0.356 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chr13_+_44121167 0.350 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr7_-_30552255 0.323 ENSMUST00000108165.1
ENSMUST00000153594.1
BC053749

cDNA sequence BC053749

chr14_-_59365410 0.315 ENSMUST00000161031.1
ENSMUST00000160425.1
Phf11d

PHD finger protein 11D

chrM_+_8600 0.312 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr17_-_57031468 0.307 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr6_+_37870786 0.291 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr7_+_101896817 0.281 ENSMUST00000143835.1
Anapc15
anaphase prompoting complex C subunit 15
chr8_+_83972951 0.275 ENSMUST00000005606.6
Prkaca
protein kinase, cAMP dependent, catalytic, alpha
chr1_-_172027269 0.273 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr2_-_37703845 0.254 ENSMUST00000155237.1
Strbp
spermatid perinuclear RNA binding protein
chr6_+_68161415 0.239 ENSMUST00000168090.1
Igkv1-115
immunoglobulin kappa variable 1-115
chr2_+_151494182 0.236 ENSMUST00000089140.6
Nsfl1c
NSFL1 (p97) cofactor (p47)
chr11_-_21371143 0.225 ENSMUST00000060895.5
Ugp2
UDP-glucose pyrophosphorylase 2
chr8_+_33599608 0.223 ENSMUST00000009774.9
Ppp2cb
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
chr15_+_75993756 0.213 ENSMUST00000089669.4
Mapk15
mitogen-activated protein kinase 15
chr8_-_104534630 0.191 ENSMUST00000162466.1
ENSMUST00000034349.9
Nae1

NEDD8 activating enzyme E1 subunit 1

chr3_-_89101907 0.185 ENSMUST00000081848.8
Fdps
farnesyl diphosphate synthetase
chr5_+_115605642 0.176 ENSMUST00000094427.3
Gcn1l1
GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
chr8_-_21906412 0.163 ENSMUST00000051965.4
Defb11
defensin beta 11
chr7_-_27195727 0.159 ENSMUST00000163311.2
ENSMUST00000126211.1
Snrpa

small nuclear ribonucleoprotein polypeptide A

chr3_-_90389884 0.157 ENSMUST00000029541.5
Slc27a3
solute carrier family 27 (fatty acid transporter), member 3
chr5_-_34660068 0.145 ENSMUST00000041364.9
Nop14
NOP14 nucleolar protein
chr17_+_7170101 0.143 ENSMUST00000024575.6
Rps6ka2
ribosomal protein S6 kinase, polypeptide 2
chr9_-_66126559 0.134 ENSMUST00000137542.1
Snx1
sorting nexin 1
chr5_-_140702241 0.129 ENSMUST00000077890.5
ENSMUST00000041783.7
ENSMUST00000142081.1
Iqce


IQ motif containing E


chr1_+_190928492 0.124 ENSMUST00000066632.7
ENSMUST00000110899.1
Angel2

angel homolog 2 (Drosophila)

chr5_+_143909964 0.105 ENSMUST00000148011.1
ENSMUST00000110709.3
Pms2

postmeiotic segregation increased 2 (S. cerevisiae)

chr2_+_119047116 0.105 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr5_-_143909782 0.046 ENSMUST00000031613.4
ENSMUST00000100483.2
Aimp2

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

chr1_+_174501796 0.027 ENSMUST00000030039.7
Fmn2
formin 2
chr4_-_132463873 0.013 ENSMUST00000102567.3
Med18
mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.5 1.6 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.5 1.8 GO:0090365 regulation of mRNA modification(GO:0090365)
0.4 1.3 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.4 2.6 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.4 1.8 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3 2.2 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.3 0.8 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.3 1.0 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 1.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 0.7 GO:0010757 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) negative regulation of plasminogen activation(GO:0010757) regulation of vascular wound healing(GO:0061043) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 1.9 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.2 1.1 GO:0007386 compartment pattern specification(GO:0007386)
0.2 2.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.4 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.8 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.1 2.0 GO:0007530 sex determination(GO:0007530)
0.1 0.3 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.1 0.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.1 1.7 GO:0060065 uterus development(GO:0060065)
0.1 0.9 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.6 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.4 GO:0001842 neural fold formation(GO:0001842)
0.1 1.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 2.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.5 GO:0043144 snoRNA processing(GO:0043144)
0.0 0.6 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 0.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.0 6.4 GO:0043010 camera-type eye development(GO:0043010)
0.0 6.7 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 1.1 GO:0048477 oogenesis(GO:0048477)
0.0 1.0 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.2 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 1.9 GO:0051028 mRNA transport(GO:0051028)
0.0 0.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 1.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 1.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 2.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.7 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.0 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 1.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 2.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.0 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 1.6 GO:0030496 midbody(GO:0030496)
0.0 0.5 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.5 GO:0005759 mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.4 1.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 1.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 1.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 0.8 GO:0019863 IgE binding(GO:0019863)
0.2 0.8 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.8 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 2.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 1.0 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1 1.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.5 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 1.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 2.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.2 GO:0004337 geranyltranstransferase activity(GO:0004337)
0.1 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.1 1.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 3.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 7.1 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.2 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
0.0 4.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.6 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)