Motif ID: Nkx2-1

Z-value: 0.719


Transcription factors associated with Nkx2-1:

Gene SymbolEntrez IDGene Name
Nkx2-1 ENSMUSG00000001496.9 Nkx2-1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx2-1mm10_v2_chr12_-_56536895_565369370.661.4e-08Click!


Activity profile for motif Nkx2-1.

activity profile for motif Nkx2-1


Sorted Z-values histogram for motif Nkx2-1

Sorted Z-values for motif Nkx2-1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx2-1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_103314944 8.501 ENSMUST00000179363.1
 Fam181a
family with sequence similarity 181, member A
chr5_+_128601106 7.353 ENSMUST00000117102.2
 Fzd10
frizzled homolog 10 (Drosophila)
chr8_-_46294592 7.292 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr13_-_71963713 5.879 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr1_+_12718496 5.180 ENSMUST00000088585.3
 Sulf1
sulfatase 1
chr2_-_170406501 5.056 ENSMUST00000154650.1
 Bcas1
breast carcinoma amplified sequence 1
chr19_+_44493472 4.588 ENSMUST00000041163.4
 Wnt8b
wingless related MMTV integration site 8b
chr1_+_75450699 4.563 ENSMUST00000037708.9
 Asic4
acid-sensing (proton-gated) ion channel family member 4
chr1_+_75450436 4.405 ENSMUST00000113577.1
 Asic4
acid-sensing (proton-gated) ion channel family member 4
chr4_+_89688196 4.117 ENSMUST00000052478.2
 Dmrta1
doublesex and mab-3 related transcription factor like family A1
chr17_+_34263209 3.801 ENSMUST00000040828.5
 H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr11_+_117849223 3.588 ENSMUST00000081387.4
 Birc5
baculoviral IAP repeat-containing 5
chr3_+_52268337 3.569 ENSMUST00000053764.5
 Foxo1
forkhead box O1
chrX_+_100730178 3.546 ENSMUST00000113744.1
 Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr11_+_117849286 3.224 ENSMUST00000093906.4
 Birc5
baculoviral IAP repeat-containing 5
chrX_+_58030999 3.202 ENSMUST00000088631.4
ENSMUST00000088629.3
 Zic3

zinc finger protein of the cerebellum 3

chr4_-_9643638 3.193 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
 Asph




aspartate-beta-hydroxylase




chr14_-_47411666 3.133 ENSMUST00000111778.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chrX_-_142390334 2.904 ENSMUST00000112907.1
 Acsl4
acyl-CoA synthetase long-chain family member 4
chr17_+_47737030 2.901 ENSMUST00000086932.3
 Tfeb
transcription factor EB
chr2_+_121506715 2.812 ENSMUST00000028676.5
 Wdr76
WD repeat domain 76
chr4_+_45203921 2.809 ENSMUST00000107804.1
 Frmpd1
FERM and PDZ domain containing 1
chr1_-_163725123 2.809 ENSMUST00000159679.1
 Mettl11b
methyltransferase like 11B
chrX_+_58030622 2.743 ENSMUST00000088627.4
 Zic3
zinc finger protein of the cerebellum 3
chr1_+_153900572 2.697 ENSMUST00000139476.1
 Glul
glutamate-ammonia ligase (glutamine synthetase)
chr10_+_88091070 2.657 ENSMUST00000048621.7
 Pmch
pro-melanin-concentrating hormone
chr15_-_88978958 2.635 ENSMUST00000042594.6
ENSMUST00000109368.1
 Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr16_+_48994185 2.561 ENSMUST00000117994.1
ENSMUST00000048374.5
 C330027C09Rik

RIKEN cDNA C330027C09 gene

chr2_+_121506748 2.512 ENSMUST00000099473.3
ENSMUST00000110602.2
 Wdr76

WD repeat domain 76

chr1_+_97024681 2.265 ENSMUST00000054664.7
 Gm6430
predicted gene 6430
chr14_-_30915387 2.250 ENSMUST00000166622.1
 Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr12_+_78748947 2.210 ENSMUST00000082024.5
 Mpp5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr4_+_98923845 2.133 ENSMUST00000091358.4
 Usp1
ubiquitin specific peptidase 1
chr1_-_181842334 2.039 ENSMUST00000005003.6
 Lbr
lamin B receptor
chr2_-_158146385 2.014 ENSMUST00000103122.3
 Tgm2
transglutaminase 2, C polypeptide
chr2_+_71786923 2.008 ENSMUST00000112101.1
ENSMUST00000028522.3
 Itga6

integrin alpha 6

chr4_-_21685782 1.966 ENSMUST00000076206.4
 Prdm13
PR domain containing 13
chr9_-_71896047 1.964 ENSMUST00000184448.1
 Tcf12
transcription factor 12
chr11_+_63133068 1.883 ENSMUST00000108700.1
 Pmp22
peripheral myelin protein 22
chr11_-_78550777 1.829 ENSMUST00000103242.4
 Tmem97
transmembrane protein 97
chr2_+_80315461 1.820 ENSMUST00000028392.7
 Dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr12_-_30911593 1.806 ENSMUST00000062740.7
ENSMUST00000074038.5
 Acp1

acid phosphatase 1, soluble

chr14_+_27238018 1.799 ENSMUST00000049206.5
 Arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chr2_+_10153563 1.766 ENSMUST00000026886.7
 Itih5
inter-alpha (globulin) inhibitor H5
chr4_-_141874879 1.709 ENSMUST00000036854.3
 Efhd2
EF hand domain containing 2
chr17_-_25861456 1.648 ENSMUST00000079461.8
ENSMUST00000176923.1
 Wdr90

WD repeat domain 90

chr6_-_101377342 1.520 ENSMUST00000151175.1
 Pdzrn3
PDZ domain containing RING finger 3
chr9_+_119937606 1.475 ENSMUST00000035100.5
 Ttc21a
tetratricopeptide repeat domain 21A
chrX_-_111463103 1.407 ENSMUST00000137712.2
 Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr17_-_34627365 1.406 ENSMUST00000064953.8
ENSMUST00000170345.1
ENSMUST00000171121.2
ENSMUST00000168391.2
ENSMUST00000169067.2
 Ppt2




palmitoyl-protein thioesterase 2




chr7_+_128246953 1.164 ENSMUST00000167965.1
 Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr7_+_51879041 1.125 ENSMUST00000107591.2
 Gas2
growth arrest specific 2
chr4_+_120854786 1.117 ENSMUST00000071093.2
 Rims3
regulating synaptic membrane exocytosis 3
chr11_+_94741782 1.112 ENSMUST00000021240.6
 Cdc34-ps
cell division cycle 34 homolog, pseudogene (S. cerevisiae)
chr7_+_35397046 1.108 ENSMUST00000079414.5
 Cep89
centrosomal protein 89
chr1_+_135232045 1.083 ENSMUST00000110798.3
 Gm4204
predicted gene 4204
chr7_+_128246812 1.068 ENSMUST00000164710.1
ENSMUST00000070656.5
 Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr7_+_51878967 1.047 ENSMUST00000051912.6
 Gas2
growth arrest specific 2
chr15_+_99702278 1.019 ENSMUST00000023759.4
 Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr4_-_41517326 1.003 ENSMUST00000030152.6
ENSMUST00000095126.4
 1110017D15Rik

RIKEN cDNA 1110017D15 gene

chr16_+_44139821 1.002 ENSMUST00000159514.1
ENSMUST00000161326.1
ENSMUST00000063520.8
ENSMUST00000063542.7
 Naa50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr9_+_75775355 0.989 ENSMUST00000012281.7
 Bmp5
bone morphogenetic protein 5
chrX_-_111463043 0.964 ENSMUST00000065976.5
 Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr16_-_76403673 0.891 ENSMUST00000052867.7
 Gm9843
predicted gene 9843
chr4_+_62360695 0.873 ENSMUST00000084526.5
 Slc31a1
solute carrier family 31, member 1
chrX_+_7762652 0.853 ENSMUST00000077680.3
ENSMUST00000079542.6
ENSMUST00000115679.1
ENSMUST00000137467.1
 Tfe3



transcription factor E3



chr10_+_22645011 0.850 ENSMUST00000042261.4
 Slc2a12
solute carrier family 2 (facilitated glucose transporter), member 12
chr4_-_109665249 0.850 ENSMUST00000063531.4
 Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr9_+_46012810 0.845 ENSMUST00000126865.1
 Sik3
SIK family kinase 3
chr15_-_10470490 0.831 ENSMUST00000136591.1
 Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr7_+_35186370 0.766 ENSMUST00000135452.1
ENSMUST00000001854.5
 Slc7a10

solute carrier family 7 (cationic amino acid transporter, y+ system), member 10

chr8_+_23411490 0.704 ENSMUST00000033952.7
 Sfrp1
secreted frizzled-related protein 1
chr11_+_85832551 0.689 ENSMUST00000000095.6
 Tbx2
T-box 2
chr12_-_85824506 0.665 ENSMUST00000021676.5
ENSMUST00000142331.1
 0610007P14Rik

RIKEN cDNA 0610007P14 gene

chrX_+_56963325 0.638 ENSMUST00000096431.3
 Gpr112
G protein-coupled receptor 112
chr17_-_34628005 0.622 ENSMUST00000166040.2
 Ppt2
palmitoyl-protein thioesterase 2
chr17_-_25570678 0.603 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr9_+_46012822 0.567 ENSMUST00000120463.2
ENSMUST00000120247.1
 Sik3

SIK family kinase 3

chr13_+_55635002 0.548 ENSMUST00000172272.1
ENSMUST00000099479.3
 Ddx46

DEAD (Asp-Glu-Ala-Asp) box polypeptide 46

chr6_-_114921778 0.546 ENSMUST00000032459.7
 Vgll4
vestigial like 4 (Drosophila)
chr11_-_86257518 0.506 ENSMUST00000136469.1
ENSMUST00000018212.6
 Ints2

integrator complex subunit 2

chr4_-_118490030 0.504 ENSMUST00000047421.5
 Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr11_-_86257553 0.493 ENSMUST00000132024.1
ENSMUST00000139285.1
 Ints2

integrator complex subunit 2

chr3_-_95411176 0.469 ENSMUST00000177599.1
 Gm5070
predicted gene 5070
chr3_-_150073620 0.446 ENSMUST00000057740.5
 Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr17_-_32388885 0.427 ENSMUST00000087703.5
ENSMUST00000170603.1
 Wiz

widely-interspaced zinc finger motifs

chr11_+_70432627 0.375 ENSMUST00000084954.6
ENSMUST00000108568.3
ENSMUST00000079056.2
ENSMUST00000102564.4
ENSMUST00000124943.1
ENSMUST00000150076.1
ENSMUST00000102563.1
 Arrb2






arrestin, beta 2






chr14_+_7817957 0.358 ENSMUST00000052678.8
 Flnb
filamin, beta
chr2_+_80638798 0.347 ENSMUST00000028382.6
ENSMUST00000124377.1
 Nup35

nucleoporin 35

chr7_+_102225812 0.304 ENSMUST00000142873.1
 Pgap2
post-GPI attachment to proteins 2
chr13_+_12565868 0.289 ENSMUST00000071973.6
 Ero1lb
ERO1-like beta (S. cerevisiae)
chr11_+_80428598 0.182 ENSMUST00000173938.1
ENSMUST00000017572.7
 Psmd11

proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

chr5_-_110779937 0.181 ENSMUST00000112426.1
 Pus1
pseudouridine synthase 1
chr4_-_44704006 0.163 ENSMUST00000146335.1
 Pax5
paired box gene 5
chrX_-_73966329 0.148 ENSMUST00000114372.2
ENSMUST00000033761.6
 Hcfc1

host cell factor C1

chr1_-_54194048 0.144 ENSMUST00000120904.1
 Hecw2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr6_+_59208870 0.114 ENSMUST00000062626.3
 Tigd2
tigger transposable element derived 2
chr10_-_123196916 0.107 ENSMUST00000020334.7
 Usp15
ubiquitin specific peptidase 15
chr1_-_162898665 0.079 ENSMUST00000111510.1
ENSMUST00000045902.6
 Fmo2

flavin containing monooxygenase 2

chr6_-_87851011 0.078 ENSMUST00000113617.1
 Cnbp
cellular nucleic acid binding protein
chr18_-_36670269 0.063 ENSMUST00000006209.4
 Sra1
steroid receptor RNA activator 1
chr12_-_71136611 0.044 ENSMUST00000021486.8
ENSMUST00000166120.1
 Timm9

translocase of inner mitochondrial membrane 9

chr3_+_37420273 0.010 ENSMUST00000029277.8
 Spata5
spermatogenesis associated 5
chr7_+_30563298 0.008 ENSMUST00000043273.9
ENSMUST00000163654.1
ENSMUST00000166510.1
ENSMUST00000163482.1
ENSMUST00000166257.1
ENSMUST00000163464.1
ENSMUST00000171850.1
ENSMUST00000168931.1
 U2af1l4







U2 small nuclear RNA auxiliary factor 1-like 4







chr7_-_28372597 0.004 ENSMUST00000144700.1
 Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.1 3.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
1.0 5.9 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
1.0 6.8 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
1.0 3.8 GO:0002339 B cell selection(GO:0002339)
0.9 7.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.9 2.7 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.9 2.7 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.7 2.0 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.5 2.6 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.5 2.0 GO:0035878 nail development(GO:0035878)
0.5 1.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.4 3.6 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.4 4.1 GO:0060179 male mating behavior(GO:0060179)
0.4 7.3 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.4 3.5 GO:0090527 actin filament reorganization(GO:0090527)
0.3 2.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 0.9 GO:0072718 response to cisplatin(GO:0072718)
0.3 2.9 GO:0032306 regulation of prostaglandin secretion(GO:0032306) embryonic process involved in female pregnancy(GO:0060136)
0.2 2.4 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.2 0.7 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 0.7 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.2 2.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.2 0.6 GO:0072034 renal vesicle induction(GO:0072034)
0.2 1.0 GO:2000065 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) regulation of cortisol biosynthetic process(GO:2000064) negative regulation of cortisol biosynthetic process(GO:2000065)
0.2 4.1 GO:0032288 myelin assembly(GO:0032288)
0.2 4.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 1.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.9 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 1.5 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.8 GO:0042940 D-amino acid transport(GO:0042940)
0.1 2.8 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 3.6 GO:0006959 humoral immune response(GO:0006959)
0.0 1.4 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 1.0 GO:0016180 snRNA processing(GO:0016180)
0.0 2.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 8.7 GO:0006814 sodium ion transport(GO:0006814)
0.0 2.6 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.0 1.1 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:0019042 viral latency(GO:0019042)
0.0 1.8 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.5 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 3.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 1.1 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.3 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 4.6 GO:0016055 Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738)
0.0 1.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.6 3.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.5 3.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 2.9 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.3 2.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 1.0 GO:0002177 manchette(GO:0002177)
0.2 3.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 2.0 GO:0030056 hemidesmosome(GO:0030056)
0.2 1.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 2.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.0 GO:0031415 NatA complex(GO:0031415)
0.1 1.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 1.0 GO:0032039 integrator complex(GO:0032039)
0.1 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 4.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.0 GO:0071564 npBAF complex(GO:0071564)
0.0 0.8 GO:0097440 apical dendrite(GO:0097440)
0.0 8.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 3.5 GO:0005884 actin filament(GO:0005884)
0.0 2.6 GO:0005901 caveola(GO:0005901)
0.0 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 7.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 8.1 GO:0009986 cell surface(GO:0009986)
0.0 0.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.9 2.7 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.5 2.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4 3.8 GO:0015643 toxic substance binding(GO:0015643)
0.4 2.0 GO:0038132 neuregulin binding(GO:0038132)
0.4 0.4 GO:0031762 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762)
0.4 8.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.4 3.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 2.1 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.3 9.0 GO:0005272 sodium channel activity(GO:0005272)
0.3 2.2 GO:0048495 Roundabout binding(GO:0048495)
0.3 2.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 1.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3 2.0 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 3.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 6.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 1.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 4.6 GO:0005109 frizzled binding(GO:0005109)
0.1 2.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 4.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.9 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 2.0 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.9 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 8.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.8 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 13.3 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.0 3.2 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 1.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 2.0 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 2.8 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 2.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 3.1 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0 1.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)