Motif ID: Nkx2-2

Z-value: 1.263


Transcription factors associated with Nkx2-2:

Gene SymbolEntrez IDGene Name
Nkx2-2 ENSMUSG00000027434.10 Nkx2-2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx2-2mm10_v2_chr2_-_147186389_147186413-0.047.7e-01Click!


Activity profile for motif Nkx2-2.

activity profile for motif Nkx2-2


Sorted Z-values histogram for motif Nkx2-2

Sorted Z-values for motif Nkx2-2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx2-2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_3018753 9.805 ENSMUST00000179272.1
Gm10719
predicted gene 10719
chr14_-_19418930 9.556 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr9_+_3034599 8.896 ENSMUST00000178641.1
Gm17535
predicted gene, 17535
chr9_+_3025417 8.157 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr9_+_3005125 7.995 ENSMUST00000179881.1
Gm11168
predicted gene 11168
chr9_+_3015654 7.921 ENSMUST00000099050.3
Gm10720
predicted gene 10720
chr9_+_3017408 7.590 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chr10_+_88091070 7.252 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chrX_+_9885622 5.446 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr3_+_5218516 3.998 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr2_-_140170528 3.818 ENSMUST00000046030.7
Esf1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr9_+_72438519 3.741 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr9_+_72438534 3.712 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr19_-_5796924 3.695 ENSMUST00000174808.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr3_+_118433797 3.194 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
Gm26871



predicted gene, 26871



chr6_+_5390387 3.177 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chr15_-_10470490 2.574 ENSMUST00000136591.1
Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr11_+_78301529 2.521 ENSMUST00000045026.3
Spag5
sperm associated antigen 5
chr4_+_59626189 2.488 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik

RIKEN cDNA E130308A19 gene

chr1_-_166002613 2.416 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
Pou2f1



POU domain, class 2, transcription factor 1



chr16_-_16527364 2.362 ENSMUST00000069284.7
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr6_+_14901344 2.262 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr7_-_6011010 2.208 ENSMUST00000086338.1
Vmn1r65
vomeronasal 1 receptor 65
chr2_+_52072823 2.183 ENSMUST00000112693.2
ENSMUST00000069794.5
Rif1

Rap1 interacting factor 1 homolog (yeast)

chr10_+_93897156 2.161 ENSMUST00000180815.1
4930471D02Rik
RIKEN cDNA 4930471D02 gene
chr4_+_115563649 2.091 ENSMUST00000141033.1
ENSMUST00000030486.8
ENSMUST00000126645.1
ENSMUST00000030480.3
Cyp4a31



cytochrome P450, family 4, subfamily a, polypeptide 31



chr5_-_123140135 1.982 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr5_-_30073554 1.931 ENSMUST00000026846.6
Tyms
thymidylate synthase
chr8_+_41239718 1.931 ENSMUST00000045218.7
Pcm1
pericentriolar material 1
chrX_+_164980592 1.908 ENSMUST00000101082.4
ENSMUST00000167446.1
ENSMUST00000057150.6
Fancb


Fanconi anemia, complementation group B


chr9_-_8004585 1.885 ENSMUST00000086580.5
ENSMUST00000065353.6
Yap1

yes-associated protein 1

chr10_+_19951055 1.881 ENSMUST00000152533.1
Map3k5
mitogen-activated protein kinase kinase kinase 5
chr2_+_23069210 1.852 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr2_+_83644435 1.835 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr6_-_120357342 1.835 ENSMUST00000163827.1
Ccdc77
coiled-coil domain containing 77
chr10_-_33995054 1.824 ENSMUST00000164429.1
Gm17567
predicted gene, 17567
chr14_+_47663756 1.805 ENSMUST00000022391.7
Ktn1
kinectin 1
chr3_+_138143429 1.796 ENSMUST00000040321.6
Trmt10a
tRNA methyltransferase 10A
chr10_+_22360552 1.788 ENSMUST00000182677.1
Raet1d
retinoic acid early transcript delta
chr13_-_103764502 1.759 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr15_-_73184840 1.748 ENSMUST00000044113.10
Ago2
argonaute RISC catalytic subunit 2
chr6_+_143285988 1.731 ENSMUST00000160951.1
D6Ertd474e
DNA segment, Chr 6, ERATO Doi 474, expressed
chrX_+_106027259 1.729 ENSMUST00000113557.1
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr10_-_12861735 1.714 ENSMUST00000076817.4
Utrn
utrophin
chr18_+_32163073 1.558 ENSMUST00000096575.3
Map3k2
mitogen-activated protein kinase kinase kinase 2
chrX_+_106027300 1.553 ENSMUST00000055941.6
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr16_+_14705832 1.503 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr6_-_120357440 1.501 ENSMUST00000112703.1
Ccdc77
coiled-coil domain containing 77
chr3_-_49757257 1.501 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr1_-_139377094 1.492 ENSMUST00000131586.1
ENSMUST00000145244.1
Crb1

crumbs homolog 1 (Drosophila)

chr3_+_138143483 1.448 ENSMUST00000162864.1
Trmt10a
tRNA methyltransferase 10A
chr3_+_5218546 1.434 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr2_-_114013619 1.428 ENSMUST00000090275.4
Gjd2
gap junction protein, delta 2
chr13_+_33964659 1.422 ENSMUST00000021843.5
ENSMUST00000058978.7
Nqo2

NAD(P)H dehydrogenase, quinone 2

chr7_-_123369870 1.398 ENSMUST00000106442.2
ENSMUST00000098060.3
ENSMUST00000167309.1
Arhgap17


Rho GTPase activating protein 17


chr2_+_71873224 1.388 ENSMUST00000006669.5
Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1
chr6_-_3494587 1.352 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr12_+_32953874 1.347 ENSMUST00000076698.5
Sypl
synaptophysin-like protein
chr2_-_77946375 1.329 ENSMUST00000065889.3
Cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr4_+_3940747 1.307 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr2_-_77946331 1.306 ENSMUST00000111821.2
ENSMUST00000111818.1
Cwc22

CWC22 spliceosome-associated protein homolog (S. cerevisiae)

chr3_-_142169311 1.291 ENSMUST00000106230.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr8_+_69300776 1.281 ENSMUST00000078257.6
D130040H23Rik
RIKEN cDNA D130040H23 gene
chr5_-_123141067 1.257 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr2_+_165655237 1.236 ENSMUST00000063433.7
Eya2
eyes absent 2 homolog (Drosophila)
chr13_+_51846673 1.194 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr12_+_38781093 1.191 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr6_-_120357422 1.189 ENSMUST00000032283.5
Ccdc77
coiled-coil domain containing 77
chr9_+_35559460 1.184 ENSMUST00000034615.3
ENSMUST00000121246.1
Pus3

pseudouridine synthase 3

chr1_-_139377041 1.171 ENSMUST00000059825.5
Crb1
crumbs homolog 1 (Drosophila)
chr14_-_72602945 1.161 ENSMUST00000162825.1
Fndc3a
fibronectin type III domain containing 3A
chr3_+_76075583 1.155 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr18_+_4993795 1.144 ENSMUST00000153016.1
Svil
supervillin
chr3_+_138143799 1.120 ENSMUST00000159622.1
Trmt10a
tRNA methyltransferase 10A
chr3_+_138143888 1.117 ENSMUST00000161141.1
Trmt10a
tRNA methyltransferase 10A
chr5_+_110839973 1.114 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr13_-_64274962 1.103 ENSMUST00000039318.8
Cdc14b
CDC14 cell division cycle 14B
chr14_-_59395381 1.083 ENSMUST00000166912.2
Phf11c
PHD finger protein 11C
chr12_+_59129720 1.072 ENSMUST00000175912.1
ENSMUST00000176892.1
Ctage5

CTAGE family, member 5

chr3_+_14533817 1.050 ENSMUST00000169079.1
ENSMUST00000091325.3
Lrrcc1

leucine rich repeat and coiled-coil domain containing 1

chr16_+_14580221 1.019 ENSMUST00000147024.1
A630010A05Rik
RIKEN cDNA A630010A05 gene
chr13_+_51645232 0.995 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chr12_+_105784694 0.993 ENSMUST00000109901.2
ENSMUST00000168186.1
ENSMUST00000163473.1
ENSMUST00000170540.1
ENSMUST00000166735.1
ENSMUST00000170002.1
Papola





poly (A) polymerase alpha





chr18_-_6241470 0.991 ENSMUST00000163210.1
Kif5b
kinesin family member 5B
chr6_+_3993776 0.976 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr6_+_14901440 0.976 ENSMUST00000128567.1
Foxp2
forkhead box P2
chr1_-_16093286 0.972 ENSMUST00000145070.1
ENSMUST00000151004.1
4930444P10Rik

RIKEN cDNA 4930444P10 gene

chr17_+_46496753 0.971 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr1_-_152386589 0.970 ENSMUST00000162371.1
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr5_+_149439706 0.957 ENSMUST00000031667.4
Tex26
testis expressed 26
chr6_+_8520008 0.947 ENSMUST00000162567.1
ENSMUST00000161217.1
Glcci1

glucocorticoid induced transcript 1

chr1_-_152386675 0.934 ENSMUST00000015124.8
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr8_+_3353415 0.932 ENSMUST00000098966.3
A430078G23Rik
RIKEN cDNA A430078G23 gene
chr18_-_6241486 0.919 ENSMUST00000025083.7
Kif5b
kinesin family member 5B
chr4_+_62619515 0.911 ENSMUST00000084521.4
ENSMUST00000107424.1
Rgs3

regulator of G-protein signaling 3

chr2_+_174076296 0.909 ENSMUST00000155000.1
ENSMUST00000134876.1
ENSMUST00000147038.1
Stx16


syntaxin 16


chr16_-_33967032 0.908 ENSMUST00000023510.6
Umps
uridine monophosphate synthetase
chr3_-_33143227 0.907 ENSMUST00000108219.1
Pex5l
peroxisomal biogenesis factor 5-like
chr17_-_15564322 0.891 ENSMUST00000147532.1
Prdm9
PR domain containing 9
chr17_+_71616215 0.872 ENSMUST00000047086.9
Wdr43
WD repeat domain 43
chr6_-_38046994 0.866 ENSMUST00000096040.4
Svopl
SV2 related protein homolog (rat)-like
chr3_+_138143846 0.826 ENSMUST00000159481.1
Trmt10a
tRNA methyltransferase 10A
chr2_-_84775420 0.820 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr7_-_43533171 0.798 ENSMUST00000004728.5
ENSMUST00000039861.5
Cd33

CD33 antigen

chr2_-_84775388 0.779 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr12_+_73901370 0.760 ENSMUST00000110461.1
Hif1a
hypoxia inducible factor 1, alpha subunit
chr2_+_140152043 0.758 ENSMUST00000104994.2
Gm17374
predicted gene, 17374
chr5_-_69592274 0.751 ENSMUST00000174233.1
ENSMUST00000120789.1
ENSMUST00000166298.1
Gnpda2


glucosamine-6-phosphate deaminase 2


chr13_-_38037069 0.744 ENSMUST00000089840.4
Cage1
cancer antigen 1
chr2_+_62664279 0.732 ENSMUST00000028257.2
Gca
grancalcin
chr4_+_43058939 0.688 ENSMUST00000079978.6
Unc13b
unc-13 homolog B (C. elegans)
chr5_-_3596071 0.683 ENSMUST00000121877.1
Rbm48
RNA binding motif protein 48
chrM_+_11734 0.679 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr18_-_84951477 0.674 ENSMUST00000025547.2
Timm21
tranlocase of inner mitochondrial membrane 21
chr1_-_88008520 0.668 ENSMUST00000040783.4
Usp40
ubiquitin specific peptidase 40
chrX_+_6415736 0.664 ENSMUST00000143641.3
Shroom4
shroom family member 4
chrX_+_68821093 0.652 ENSMUST00000096420.2
Gm14698
predicted gene 14698
chr15_-_102350692 0.642 ENSMUST00000041208.7
Aaas
achalasia, adrenocortical insufficiency, alacrimia
chr6_-_56369625 0.634 ENSMUST00000170774.1
ENSMUST00000168944.1
ENSMUST00000166890.1
Pde1c


phosphodiesterase 1C


chr13_-_64274879 0.602 ENSMUST00000109770.1
Cdc14b
CDC14 cell division cycle 14B
chr2_-_73453918 0.589 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr9_+_14860210 0.579 ENSMUST00000034408.5
ENSMUST00000115624.2
Gpr83

G protein-coupled receptor 83

chr1_+_82339049 0.564 ENSMUST00000140020.1
Rhbdd1
rhomboid domain containing 1
chr1_-_176807124 0.563 ENSMUST00000057037.7
Cep170
centrosomal protein 170
chr1_-_9748376 0.558 ENSMUST00000057438.6
Vcpip1
valosin containing protein (p97)/p47 complex interacting protein 1
chr12_+_111039334 0.550 ENSMUST00000084968.7
Rcor1
REST corepressor 1
chr19_-_29753600 0.549 ENSMUST00000175764.1
9930021J03Rik
RIKEN cDNA 9930021J03 gene
chr10_-_13388830 0.547 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr13_-_29855630 0.547 ENSMUST00000091674.5
ENSMUST00000006353.7
Cdkal1

CDK5 regulatory subunit associated protein 1-like 1

chr11_+_88973928 0.528 ENSMUST00000036649.4
ENSMUST00000107898.3
Coil

coilin

chr1_+_86064619 0.524 ENSMUST00000027432.8
Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr3_+_65528404 0.515 ENSMUST00000047906.3
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
chr11_+_97685903 0.495 ENSMUST00000107583.2
Cisd3
CDGSH iron sulfur domain 3
chr4_-_138913915 0.484 ENSMUST00000097830.3
Otud3
OTU domain containing 3
chrX_+_164269371 0.482 ENSMUST00000145412.1
ENSMUST00000033749.7
Pir

pirin

chr3_+_65528457 0.472 ENSMUST00000130705.1
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
chrX_+_101274023 0.472 ENSMUST00000117706.1
Med12
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)
chr2_+_69897255 0.466 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr12_+_55089202 0.451 ENSMUST00000021407.10
Srp54a
signal recognition particle 54A
chr5_+_105876532 0.444 ENSMUST00000150440.1
ENSMUST00000031227.4
Zfp326

zinc finger protein 326

chr6_+_137754529 0.428 ENSMUST00000087675.6
Dera
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr4_-_129640959 0.425 ENSMUST00000132217.1
ENSMUST00000130017.1
ENSMUST00000154105.1
Txlna


taxilin alpha


chr3_-_142169196 0.418 ENSMUST00000098568.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr14_+_51884982 0.416 ENSMUST00000167984.1
Mettl17
methyltransferase like 17
chr15_+_75704280 0.414 ENSMUST00000121137.1
ENSMUST00000023244.5
Rhpn1

rhophilin, Rho GTPase binding protein 1

chr13_-_18382041 0.382 ENSMUST00000139064.2
ENSMUST00000175703.2
Pou6f2

POU domain, class 6, transcription factor 2

chr12_-_32953772 0.381 ENSMUST00000180391.1
ENSMUST00000181670.1
4933406C10Rik

RIKEN cDNA 4933406C10 gene

chr1_+_179960472 0.375 ENSMUST00000097453.2
ENSMUST00000111117.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr14_-_54686060 0.368 ENSMUST00000125265.1
Acin1
apoptotic chromatin condensation inducer 1
chr4_+_126024506 0.358 ENSMUST00000106162.1
Csf3r
colony stimulating factor 3 receptor (granulocyte)
chr14_-_104522615 0.356 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr10_-_93891141 0.351 ENSMUST00000180840.1
Metap2
methionine aminopeptidase 2
chr13_+_104178797 0.347 ENSMUST00000022225.5
ENSMUST00000069187.5
Trim23

tripartite motif-containing 23

chr9_-_119322421 0.346 ENSMUST00000040853.4
Oxsr1
oxidative-stress responsive 1
chr1_+_173673651 0.315 ENSMUST00000085876.4
Pydc3
pyrin domain containing 3
chr4_+_116558056 0.310 ENSMUST00000106475.1
Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr10_+_126978690 0.309 ENSMUST00000105256.2
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr3_-_33082004 0.304 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr9_-_106891401 0.281 ENSMUST00000069036.7
Manf
mesencephalic astrocyte-derived neurotrophic factor
chr13_-_85127514 0.272 ENSMUST00000179230.1
Gm4076
predicted gene 4076
chr6_-_102464667 0.271 ENSMUST00000032159.6
Cntn3
contactin 3
chr17_+_29614800 0.271 ENSMUST00000162588.1
Rnf8
ring finger protein 8
chr17_-_83631892 0.264 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr7_+_29768552 0.260 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr16_-_85550417 0.259 ENSMUST00000175700.1
ENSMUST00000114174.2
Cyyr1

cysteine and tyrosine-rich protein 1

chr13_+_23756937 0.259 ENSMUST00000102965.2
Hist1h4b
histone cluster 1, H4b
chr4_+_125029992 0.259 ENSMUST00000030684.7
Gnl2
guanine nucleotide binding protein-like 2 (nucleolar)
chr7_-_132576372 0.251 ENSMUST00000084500.6
Oat
ornithine aminotransferase
chr18_+_12972225 0.238 ENSMUST00000025290.5
Impact
imprinted and ancient
chr13_-_41487306 0.234 ENSMUST00000021794.6
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr8_+_8689666 0.228 ENSMUST00000179702.1
B930078G14Rik
RIKEN cDNA B930078G14 gene
chr6_+_88465409 0.223 ENSMUST00000032165.9
Ruvbl1
RuvB-like protein 1
chr17_-_32822200 0.222 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr2_+_102706356 0.218 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr2_-_26237368 0.188 ENSMUST00000036187.8
Qsox2
quiescin Q6 sulfhydryl oxidase 2
chr6_-_85451248 0.182 ENSMUST00000113770.1
ENSMUST00000032080.2
Pradc1

protease-associated domain containing 1

chr3_+_76593550 0.165 ENSMUST00000162471.1
Fstl5
follistatin-like 5
chr6_-_70792155 0.162 ENSMUST00000066134.5
Rpia
ribose 5-phosphate isomerase A
chr5_+_3596066 0.161 ENSMUST00000006061.6
ENSMUST00000121291.1
ENSMUST00000142516.1
Pex1


peroxisomal biogenesis factor 1


chr11_+_3649759 0.161 ENSMUST00000140242.1
Morc2a
microrchidia 2A
chr3_-_104864420 0.158 ENSMUST00000094028.5
Capza1
capping protein (actin filament) muscle Z-line, alpha 1
chr2_-_121456693 0.157 ENSMUST00000110613.2
ENSMUST00000056312.3
Serinc4

serine incorporator 4

chr5_+_10236829 0.134 ENSMUST00000101606.3
Gm10482
predicted gene 10482
chr3_+_30792876 0.131 ENSMUST00000029256.7
Sec62
SEC62 homolog (S. cerevisiae)
chr17_+_28691419 0.129 ENSMUST00000124886.1
Mapk14
mitogen-activated protein kinase 14
chr9_-_96719549 0.127 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr19_+_44562841 0.124 ENSMUST00000040455.4
Hif1an
hypoxia-inducible factor 1, alpha subunit inhibitor
chr1_+_79776018 0.123 ENSMUST00000027464.8
Mrpl44
mitochondrial ribosomal protein L44
chr5_+_138187485 0.118 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr17_-_65884902 0.117 ENSMUST00000024905.9
Ralbp1
ralA binding protein 1
chr9_-_105395237 0.110 ENSMUST00000140851.1
Nek11
NIMA (never in mitosis gene a)-related expressed kinase 11
chr2_+_21205719 0.109 ENSMUST00000054591.3
ENSMUST00000102952.1
ENSMUST00000138965.1
ENSMUST00000138914.1
ENSMUST00000102951.1
Thnsl1




threonine synthase-like 1 (bacterial)




chr2_-_25575224 0.109 ENSMUST00000039156.6
Phpt1
phosphohistidine phosphatase 1
chr9_-_96719404 0.094 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr1_-_135688094 0.093 ENSMUST00000112103.1
Nav1
neuron navigator 1
chr2_+_180257373 0.089 ENSMUST00000059080.6
Rps21
ribosomal protein S21
chr1_+_179961110 0.081 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr3_+_81932601 0.080 ENSMUST00000029649.2
Ctso
cathepsin O
chr19_+_8819401 0.079 ENSMUST00000096753.3
Hnrnpul2
heterogeneous nuclear ribonucleoprotein U-like 2
chr9_+_74976096 0.078 ENSMUST00000081746.5
Fam214a
family with sequence similarity 214, member A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
1.1 3.3 GO:0051542 elastin biosynthetic process(GO:0051542)
0.9 3.7 GO:0035063 nuclear speck organization(GO:0035063)
0.6 1.9 GO:0046078 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177) dUMP metabolic process(GO:0046078)
0.6 1.7 GO:0007525 somatic muscle development(GO:0007525)
0.5 2.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.5 1.6 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.5 1.5 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.5 1.9 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.5 1.9 GO:0035617 stress granule disassembly(GO:0035617)
0.5 1.9 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.5 7.5 GO:0070986 left/right axis specification(GO:0070986)
0.4 1.7 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.4 1.9 GO:0060242 contact inhibition(GO:0060242)
0.4 1.9 GO:0030242 pexophagy(GO:0030242)
0.3 1.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.3 2.4 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.3 3.3 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.3 1.0 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.3 3.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 0.9 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine nucleoside monophosphate metabolic process(GO:0009129) pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.3 0.9 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.3 1.7 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.3 1.1 GO:1903463 mitotic cell cycle phase(GO:0098763) regulation of mitotic cell cycle DNA replication(GO:1903463)
0.3 3.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.3 2.4 GO:0030035 microspike assembly(GO:0030035)
0.3 0.8 GO:0051541 elastin metabolic process(GO:0051541)
0.2 6.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.2 1.2 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.2 1.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.2 0.6 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 1.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 5.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 0.9 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.2 0.7 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.2 1.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.2 1.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 2.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.8 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.1 1.2 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.3 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.6 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.4 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 3.6 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 0.5 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.3 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.1 0.2 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 1.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.7 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.3 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.1 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 1.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.4 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 1.2 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.3 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.9 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 1.0 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.6 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0036166 phenotypic switching(GO:0036166)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 1.4 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 1.4 GO:0007601 visual perception(GO:0007601)
0.0 0.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 1.0 GO:0007127 meiosis I(GO:0007127)
0.0 0.3 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.4 GO:0051297 centrosome organization(GO:0051297)
0.0 0.4 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 4.3 GO:0008380 RNA splicing(GO:0008380)
0.0 0.7 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.7 2.6 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.6 1.8 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.5 1.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.4 1.9 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 2.2 GO:0001940 male pronucleus(GO:0001940)
0.3 1.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 1.7 GO:0070578 RISC-loading complex(GO:0070578)
0.2 4.5 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.7 GO:0070938 contractile ring(GO:0070938)
0.1 1.9 GO:0035253 ciliary rootlet(GO:0035253)
0.1 7.5 GO:0005882 intermediate filament(GO:0005882)
0.1 0.7 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.4 GO:0005922 connexon complex(GO:0005922)
0.1 1.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 2.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.5 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.9 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0016460 myosin II complex(GO:0016460)
0.0 0.4 GO:0061574 ASAP complex(GO:0061574)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 2.7 GO:0005902 microvillus(GO:0005902)
0.0 1.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.4 GO:0030175 filopodium(GO:0030175)
0.0 3.1 GO:0016607 nuclear speck(GO:0016607)
0.0 1.8 GO:0072562 blood microparticle(GO:0072562)
0.0 3.1 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.9 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 12.2 GO:0005730 nucleolus(GO:0005730)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 4.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0000922 spindle pole(GO:0000922)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.4 GO:0030496 midbody(GO:0030496)
0.0 2.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.6 1.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.4 2.1 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.4 7.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 1.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 1.9 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.2 1.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 0.7 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.2 1.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 1.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 0.8 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 1.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 5.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.9 GO:0005542 folic acid binding(GO:0005542)
0.1 6.3 GO:0000049 tRNA binding(GO:0000049)
0.1 1.7 GO:0017166 vinculin binding(GO:0017166)
0.1 3.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 1.6 GO:0001848 complement binding(GO:0001848)
0.1 0.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 1.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.0 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.1 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.5 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.9 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 4.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.9 GO:0045502 dynein binding(GO:0045502)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.5 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 2.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0 2.0 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.2 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)