Motif ID: Nkx2-3
Z-value: 0.960
Transcription factors associated with Nkx2-3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Nkx2-3 | ENSMUSG00000044220.12 | Nkx2-3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nkx2-3 | mm10_v2_chr19_+_43612299_43612325 | 0.15 | 2.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 5.8 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 1.3 | 3.8 | GO:0090425 | hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
| 1.3 | 3.8 | GO:0060166 | olfactory pit development(GO:0060166) |
| 1.3 | 10.1 | GO:2000809 | positive regulation of synaptic vesicle clustering(GO:2000809) |
| 1.3 | 5.0 | GO:0006538 | glutamate catabolic process(GO:0006538) |
| 1.2 | 3.7 | GO:2001139 | negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139) |
| 1.1 | 3.3 | GO:0007521 | muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
| 1.0 | 2.0 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
| 1.0 | 30.6 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.8 | 9.3 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.8 | 5.9 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.8 | 4.5 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.7 | 3.6 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.7 | 2.1 | GO:0038095 | positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) |
| 0.7 | 2.0 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.7 | 12.0 | GO:0021860 | pyramidal neuron development(GO:0021860) |
| 0.7 | 2.6 | GO:0098735 | positive regulation of guanylate cyclase activity(GO:0031284) positive regulation of the force of heart contraction(GO:0098735) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) |
| 0.6 | 5.2 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.6 | 5.1 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.5 | 1.5 | GO:0003289 | atrial septum primum morphogenesis(GO:0003289) noradrenergic neuron differentiation(GO:0003357) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.5 | 1.9 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.4 | 4.3 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.4 | 2.5 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
| 0.4 | 1.6 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.4 | 2.0 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
| 0.4 | 2.0 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.4 | 3.9 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.4 | 0.8 | GO:0060023 | soft palate development(GO:0060023) |
| 0.4 | 1.1 | GO:0060060 | post-embryonic retina morphogenesis in camera-type eye(GO:0060060) |
| 0.4 | 2.2 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.4 | 1.4 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.4 | 6.0 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
| 0.4 | 1.8 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
| 0.3 | 1.0 | GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
| 0.3 | 0.6 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 0.3 | 1.6 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.3 | 4.1 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
| 0.3 | 6.9 | GO:0048670 | regulation of collateral sprouting(GO:0048670) |
| 0.3 | 1.3 | GO:0030242 | pexophagy(GO:0030242) |
| 0.2 | 2.4 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.2 | 0.7 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 0.2 | 0.7 | GO:0010871 | negative regulation of receptor biosynthetic process(GO:0010871) |
| 0.2 | 8.1 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
| 0.2 | 1.0 | GO:0090148 | membrane fission(GO:0090148) |
| 0.2 | 1.1 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.2 | 3.7 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.2 | 1.5 | GO:0098907 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907) |
| 0.2 | 1.0 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.1 | 1.2 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.1 | 0.6 | GO:0050913 | sensory perception of bitter taste(GO:0050913) |
| 0.1 | 2.8 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.1 | 0.3 | GO:0009838 | abscission(GO:0009838) |
| 0.1 | 0.7 | GO:0071476 | hypotonic response(GO:0006971) cellular hypotonic response(GO:0071476) |
| 0.1 | 1.5 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 1.3 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.1 | 1.7 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.1 | 0.9 | GO:1900194 | negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194) |
| 0.1 | 0.2 | GO:0035864 | response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) |
| 0.1 | 3.8 | GO:0060074 | synapse maturation(GO:0060074) |
| 0.1 | 9.2 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.1 | 0.5 | GO:0034285 | response to sucrose(GO:0009744) response to disaccharide(GO:0034285) |
| 0.1 | 0.8 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
| 0.1 | 1.1 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.1 | 1.5 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.1 | 0.2 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
| 0.1 | 2.2 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.1 | 0.4 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.1 | 1.2 | GO:0021800 | cerebral cortex tangential migration(GO:0021800) |
| 0.1 | 0.8 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 0.1 | 2.7 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.1 | 2.9 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.1 | 7.9 | GO:0007601 | visual perception(GO:0007601) |
| 0.1 | 1.2 | GO:0060746 | parental behavior(GO:0060746) |
| 0.1 | 0.5 | GO:0090188 | negative regulation of pancreatic juice secretion(GO:0090188) |
| 0.1 | 3.2 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.1 | 1.3 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
| 0.1 | 7.2 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.1 | 0.4 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.1 | 1.1 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
| 0.1 | 0.2 | GO:0060489 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) |
| 0.1 | 0.3 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 4.6 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
| 0.1 | 0.5 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.1 | 1.2 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.0 | 2.4 | GO:0001541 | ovarian follicle development(GO:0001541) |
| 0.0 | 4.6 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
| 0.0 | 0.5 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.0 | 1.9 | GO:0031018 | endocrine pancreas development(GO:0031018) |
| 0.0 | 0.3 | GO:0045945 | positive regulation of transcription from RNA polymerase III promoter(GO:0045945) |
| 0.0 | 0.4 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.0 | 0.9 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 3.9 | GO:0098792 | xenophagy(GO:0098792) |
| 0.0 | 2.1 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.0 | 1.1 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.0 | 0.3 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.0 | 1.1 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 1.0 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.0 | 1.0 | GO:1904030 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
| 0.0 | 1.2 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.1 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
| 0.0 | 0.4 | GO:0032402 | melanosome transport(GO:0032402) pigment granule transport(GO:0051904) |
| 0.0 | 0.3 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.0 | 0.1 | GO:0046208 | spermine catabolic process(GO:0046208) |
| 0.0 | 0.4 | GO:0035455 | response to interferon-alpha(GO:0035455) |
| 0.0 | 3.1 | GO:0051291 | protein heterooligomerization(GO:0051291) |
| 0.0 | 0.5 | GO:0035774 | positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774) |
| 0.0 | 1.0 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.0 | 0.7 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 1.9 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 1.9 | GO:0050806 | positive regulation of synaptic transmission(GO:0050806) |
| 0.0 | 0.3 | GO:2000171 | negative regulation of dendrite development(GO:2000171) |
| 0.0 | 0.2 | GO:0001553 | luteinization(GO:0001553) |
| 0.0 | 0.1 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.0 | 0.2 | GO:0071624 | positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.0 | 0.8 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 6.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 1.2 | 3.7 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 1.0 | 8.6 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.8 | 2.3 | GO:0005595 | collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934) |
| 0.6 | 10.7 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.6 | 7.2 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.4 | 1.8 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.4 | 4.7 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.4 | 1.1 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.3 | 5.2 | GO:0031045 | dense core granule(GO:0031045) |
| 0.3 | 1.0 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.3 | 4.4 | GO:0005922 | connexon complex(GO:0005922) |
| 0.3 | 8.4 | GO:0030673 | axolemma(GO:0030673) |
| 0.2 | 0.7 | GO:0034684 | integrin alphav-beta5 complex(GO:0034684) |
| 0.2 | 3.6 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
| 0.2 | 6.6 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.2 | 4.8 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.2 | 3.3 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.2 | 5.0 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.2 | 0.9 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.1 | 1.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 0.4 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
| 0.1 | 0.6 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.1 | 3.3 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 1.5 | GO:0031430 | M band(GO:0031430) |
| 0.1 | 7.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 1.3 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.1 | 1.7 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 1.0 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 0.8 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 0.2 | GO:0060187 | cell pole(GO:0060187) |
| 0.1 | 3.2 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 0.4 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.0 | 2.3 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 0.3 | GO:0090543 | Flemming body(GO:0090543) |
| 0.0 | 2.4 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 1.3 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 1.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 4.3 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 3.3 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
| 0.0 | 3.7 | GO:0042641 | actomyosin(GO:0042641) |
| 0.0 | 9.1 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.0 | 0.1 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.0 | 1.4 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.1 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 3.3 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 8.7 | GO:0005874 | microtubule(GO:0005874) |
| 0.0 | 1.0 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 9.2 | GO:0045202 | synapse(GO:0045202) |
| 0.0 | 1.1 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 1.3 | GO:0005938 | cell cortex(GO:0005938) |
| 0.0 | 2.7 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.2 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 0.7 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 0.4 | GO:0032993 | protein-DNA complex(GO:0032993) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 3.7 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 1.2 | 3.7 | GO:0046911 | hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 1.1 | 8.6 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 1.0 | 6.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 1.0 | 3.9 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.9 | 2.8 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.9 | 2.6 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.7 | 4.3 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.7 | 5.0 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.7 | 2.0 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.7 | 2.6 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.6 | 5.8 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.5 | 12.0 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.5 | 2.4 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.5 | 2.4 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.5 | 3.8 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.4 | 5.1 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.4 | 3.3 | GO:0043495 | protein anchor(GO:0043495) |
| 0.4 | 4.1 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
| 0.3 | 1.0 | GO:0036004 | GAF domain binding(GO:0036004) |
| 0.3 | 2.5 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.3 | 1.3 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.3 | 3.3 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.3 | 4.6 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 0.2 | 1.4 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.2 | 3.9 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.2 | 7.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.2 | 0.8 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
| 0.2 | 1.0 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.2 | 1.5 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.2 | 3.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.2 | 5.2 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.2 | 3.6 | GO:0031402 | sodium ion binding(GO:0031402) |
| 0.2 | 3.8 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.2 | 2.1 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.2 | 4.5 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 1.2 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.1 | 1.2 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.1 | 1.3 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 2.8 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.1 | 0.7 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132) |
| 0.1 | 2.7 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.1 | 0.5 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.1 | 0.7 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 1.1 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 7.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 2.7 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 19.9 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 3.1 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.1 | 0.2 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.1 | 1.1 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.0 | 1.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.8 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 1.7 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.0 | 1.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 2.6 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.1 | GO:0046592 | polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901) |
| 0.0 | 2.9 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 4.2 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.8 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 1.3 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 6.0 | GO:0003729 | mRNA binding(GO:0003729) |
| 0.0 | 1.9 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.6 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.8 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.0 | 0.7 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.8 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.1 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.0 | 0.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.2 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
| 0.0 | 0.2 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.0 | 0.2 | GO:0008758 | thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606) |
| 0.0 | 1.5 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 0.4 | GO:0045502 | dynein binding(GO:0045502) |
| 0.0 | 0.8 | GO:0005088 | Ras guanyl-nucleotide exchange factor activity(GO:0005088) |
| 0.0 | 0.6 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.4 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 3.4 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 2.6 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 0.4 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
