Motif ID: Nkx2-9

Z-value: 0.764


Transcription factors associated with Nkx2-9:

Gene SymbolEntrez IDGene Name
Nkx2-9 ENSMUSG00000058669.7 Nkx2-9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx2-9mm10_v2_chr12_-_56613270_566132910.557.1e-06Click!


Activity profile for motif Nkx2-9.

activity profile for motif Nkx2-9


Sorted Z-values histogram for motif Nkx2-9

Sorted Z-values for motif Nkx2-9



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx2-9

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_71963713 8.752 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr12_-_56536895 7.323 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr8_-_46294592 4.776 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr13_+_72632597 4.323 ENSMUST00000172353.1
Irx2
Iroquois related homeobox 2 (Drosophila)
chr4_-_72852622 4.289 ENSMUST00000179234.1
ENSMUST00000078617.4
Aldoart1

aldolase 1 A, retrogene 1

chr11_+_117849223 4.157 ENSMUST00000081387.4
Birc5
baculoviral IAP repeat-containing 5
chr10_+_88091070 4.076 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr11_+_88718442 4.011 ENSMUST00000138007.1
C030037D09Rik
RIKEN cDNA C030037D09 gene
chr3_+_122419772 3.936 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr11_+_117849286 3.751 ENSMUST00000093906.4
Birc5
baculoviral IAP repeat-containing 5
chr6_+_66896397 3.685 ENSMUST00000043148.6
ENSMUST00000114228.1
ENSMUST00000114227.1
ENSMUST00000114226.1
ENSMUST00000114225.1
ENSMUST00000114224.1
Gng12





guanine nucleotide binding protein (G protein), gamma 12





chr7_-_142576492 3.314 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr8_+_95633500 3.099 ENSMUST00000034094.9
Gins3
GINS complex subunit 3 (Psf3 homolog)
chr6_-_6217023 3.055 ENSMUST00000015256.8
Slc25a13
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr2_+_173022360 2.857 ENSMUST00000173997.1
Rbm38
RNA binding motif protein 38
chr16_-_33380717 2.846 ENSMUST00000180923.1
1700007L15Rik
RIKEN cDNA 1700007L15 gene
chr6_+_66896480 2.773 ENSMUST00000114222.1
Gng12
guanine nucleotide binding protein (G protein), gamma 12
chr5_-_62765618 2.748 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_+_4925802 2.679 ENSMUST00000057612.7
Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chr3_-_95411176 2.447 ENSMUST00000177599.1
Gm5070
predicted gene 5070
chr1_-_181842334 2.428 ENSMUST00000005003.6
Lbr
lamin B receptor
chr16_-_59555752 2.389 ENSMUST00000179383.1
ENSMUST00000044604.8
Crybg3

beta-gamma crystallin domain containing 3

chr16_-_35490873 2.383 ENSMUST00000023550.7
Pdia5
protein disulfide isomerase associated 5
chr1_-_128103016 2.313 ENSMUST00000097597.2
Zranb3
zinc finger, RAN-binding domain containing 3
chr9_-_54647199 2.246 ENSMUST00000128163.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr17_+_34263209 2.068 ENSMUST00000040828.5
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr10_+_63061582 2.067 ENSMUST00000020266.8
ENSMUST00000178684.1
Pbld1

phenazine biosynthesis-like protein domain containing 1

chr16_+_30065333 1.853 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr2_+_80315461 1.827 ENSMUST00000028392.7
Dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr4_-_21685782 1.766 ENSMUST00000076206.4
Prdm13
PR domain containing 13
chr12_+_24572276 1.758 ENSMUST00000085553.5
Grhl1
grainyhead-like 1 (Drosophila)
chr16_+_70313949 1.739 ENSMUST00000163832.1
Gbe1
glucan (1,4-alpha-), branching enzyme 1
chr7_+_70388305 1.700 ENSMUST00000080024.5
B130024G19Rik
RIKEN cDNA B130024G19 gene
chr4_+_8690399 1.696 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr12_-_24493656 1.687 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr6_+_135362931 1.627 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr1_-_131097535 1.622 ENSMUST00000016672.4
Mapkapk2
MAP kinase-activated protein kinase 2
chr6_-_101377342 1.612 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr15_-_10470490 1.587 ENSMUST00000136591.1
Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr15_-_88978958 1.559 ENSMUST00000042594.6
ENSMUST00000109368.1
Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chrX_-_49788204 1.558 ENSMUST00000114893.1
Igsf1
immunoglobulin superfamily, member 1
chr19_+_43752996 1.541 ENSMUST00000026199.7
ENSMUST00000112047.3
ENSMUST00000153295.1
Cutc


cutC copper transporter homolog (E.coli)


chr16_-_46155077 1.506 ENSMUST00000059524.5
Gm4737
predicted gene 4737
chr2_-_129699833 1.504 ENSMUST00000028883.5
Pdyn
prodynorphin
chr11_+_108920342 1.424 ENSMUST00000052915.7
Axin2
axin2
chr18_+_73859366 1.403 ENSMUST00000120033.1
ENSMUST00000179472.1
ENSMUST00000119239.1
Mro


maestro


chrX_+_42149534 1.377 ENSMUST00000127618.1
Stag2
stromal antigen 2
chr11_-_100759740 1.358 ENSMUST00000107361.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr11_-_22982090 1.333 ENSMUST00000093270.5
ENSMUST00000071068.8
ENSMUST00000159081.1
ENSMUST00000160826.1
Commd1


RP23-242C19.7
COMM domain containing 1


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 (B3gnt2), transcript variant 2, mRNA
chr17_-_25861456 1.319 ENSMUST00000079461.8
ENSMUST00000176923.1
Wdr90

WD repeat domain 90

chr11_+_87699897 1.316 ENSMUST00000040089.4
Rnf43
ring finger protein 43
chr10_+_94198955 1.292 ENSMUST00000020209.9
ENSMUST00000179990.1
Ndufa12

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12

chr17_+_46496753 1.286 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chrX_+_42149288 1.268 ENSMUST00000115073.2
ENSMUST00000115072.1
Stag2

stromal antigen 2

chr2_+_181767040 1.241 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chrX_+_56779437 1.212 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr6_+_122707489 1.199 ENSMUST00000112581.1
ENSMUST00000112580.1
ENSMUST00000012540.4
Nanog


Nanog homeobox


chr18_-_35662180 1.187 ENSMUST00000025209.4
ENSMUST00000096573.2
Spata24

spermatogenesis associated 24

chr13_+_75839868 1.176 ENSMUST00000022082.7
Glrx
glutaredoxin
chr16_-_76403673 1.083 ENSMUST00000052867.7
Gm9843
predicted gene 9843
chr7_-_101921186 1.068 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
Lrrc51


leucine rich repeat containing 51


chr5_-_45639501 1.046 ENSMUST00000016023.7
Fam184b
family with sequence similarity 184, member B
chr14_+_53665912 0.980 ENSMUST00000181768.1
Trav3-3
T cell receptor alpha variable 3-3
chr9_+_75775355 0.974 ENSMUST00000012281.7
Bmp5
bone morphogenetic protein 5
chr7_+_35186370 0.955 ENSMUST00000135452.1
ENSMUST00000001854.5
Slc7a10

solute carrier family 7 (cationic amino acid transporter, y+ system), member 10

chr10_-_59221757 0.939 ENSMUST00000165971.1
Sept10
septin 10
chr16_+_32271468 0.931 ENSMUST00000093183.3
Smco1
single-pass membrane protein with coiled-coil domains 1
chr7_+_75610038 0.905 ENSMUST00000125771.1
Akap13
A kinase (PRKA) anchor protein 13
chr7_-_101921175 0.897 ENSMUST00000098236.2
Lrrc51
leucine rich repeat containing 51
chr1_+_87264345 0.890 ENSMUST00000118687.1
ENSMUST00000027472.6
Efhd1

EF hand domain containing 1

chrX_-_102189371 0.861 ENSMUST00000033683.7
Rps4x
ribosomal protein S4, X-linked
chr2_-_6130117 0.858 ENSMUST00000126551.1
ENSMUST00000054254.5
ENSMUST00000114942.2
Proser2


proline and serine rich 2


chr9_+_74861888 0.834 ENSMUST00000056006.9
Onecut1
one cut domain, family member 1
chr3_-_153912966 0.816 ENSMUST00000089950.4
Rabggtb
RAB geranylgeranyl transferase, b subunit
chr11_-_109363654 0.782 ENSMUST00000070956.3
Gm11696
predicted gene 11696
chr4_+_44981389 0.767 ENSMUST00000045078.6
ENSMUST00000128973.1
ENSMUST00000151148.1
Grhpr


glyoxylate reductase/hydroxypyruvate reductase


chr5_+_67260696 0.710 ENSMUST00000161233.1
ENSMUST00000160352.1
Tmem33

transmembrane protein 33

chr7_+_30280094 0.685 ENSMUST00000108187.1
ENSMUST00000014072.5
Thap8

THAP domain containing 8

chr9_-_56161051 0.664 ENSMUST00000034876.8
Tspan3
tetraspanin 3
chr13_-_107890059 0.644 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr10_+_68723723 0.636 ENSMUST00000080995.6
Tmem26
transmembrane protein 26
chr1_-_63176653 0.622 ENSMUST00000027111.8
ENSMUST00000168099.2
Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

chr6_-_37442095 0.622 ENSMUST00000041093.5
Creb3l2
cAMP responsive element binding protein 3-like 2
chr2_-_25575224 0.559 ENSMUST00000039156.6
Phpt1
phosphohistidine phosphatase 1
chrX_+_135993820 0.528 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr2_+_103969528 0.490 ENSMUST00000123437.1
ENSMUST00000163256.1
Lmo2

LIM domain only 2

chr1_+_9545397 0.453 ENSMUST00000072079.7
Rrs1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chrX_+_152001845 0.451 ENSMUST00000026289.3
ENSMUST00000112617.3
Hsd17b10

hydroxysteroid (17-beta) dehydrogenase 10

chrX_+_7878298 0.402 ENSMUST00000033495.8
Pim2
proviral integration site 2
chrX_+_7899350 0.397 ENSMUST00000033498.3
Timm17b
translocase of inner mitochondrial membrane 17b
chr5_+_30105161 0.362 ENSMUST00000058045.4
Gareml
GRB2 associated, regulator of MAPK1-like
chr7_-_126475082 0.334 ENSMUST00000032978.6
Sh2b1
SH2B adaptor protein 1
chr5_+_67260565 0.309 ENSMUST00000037918.5
ENSMUST00000162543.1
Tmem33

transmembrane protein 33

chr3_-_34351685 0.306 ENSMUST00000174114.1
Gm20514
predicted gene 20514
chr12_-_55080098 0.241 ENSMUST00000021406.5
2700097O09Rik
RIKEN cDNA 2700097O09 gene
chr5_+_147430407 0.232 ENSMUST00000176600.1
Pan3
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr6_-_87851011 0.231 ENSMUST00000113617.1
Cnbp
cellular nucleic acid binding protein
chr3_+_138277489 0.216 ENSMUST00000004232.9
Adh1
alcohol dehydrogenase 1 (class I)
chr6_+_42286676 0.204 ENSMUST00000031894.6
Clcn1
chloride channel 1
chr12_-_71136611 0.195 ENSMUST00000021486.8
ENSMUST00000166120.1
Timm9

translocase of inner mitochondrial membrane 9

chr19_-_43752924 0.174 ENSMUST00000045562.5
Cox15
cytochrome c oxidase assembly protein 15
chr6_-_142507805 0.170 ENSMUST00000134191.1
ENSMUST00000032373.5
Ldhb

lactate dehydrogenase B

chr1_+_74153981 0.151 ENSMUST00000027372.7
ENSMUST00000106899.2
Cxcr2

chemokine (C-X-C motif) receptor 2

chr11_+_114668524 0.109 ENSMUST00000106602.3
ENSMUST00000077915.3
ENSMUST00000106599.1
ENSMUST00000082092.4
Rpl38



ribosomal protein L38



chr11_+_72607221 0.107 ENSMUST00000021148.6
ENSMUST00000138247.1
Ube2g1

ubiquitin-conjugating enzyme E2G 1

chr15_+_58933774 0.100 ENSMUST00000022980.3
Ndufb9
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9
chr4_-_41275091 0.091 ENSMUST00000030143.6
ENSMUST00000108068.1
Ubap2

ubiquitin-associated protein 2

chr13_-_51567084 0.077 ENSMUST00000021898.5
Shc3
src homology 2 domain-containing transforming protein C3
chr2_+_80638798 0.076 ENSMUST00000028382.6
ENSMUST00000124377.1
Nup35

nucleoporin 35

chr7_-_102018139 0.069 ENSMUST00000094134.3
Il18bp
interleukin 18 binding protein
chr4_-_141664063 0.061 ENSMUST00000084203.4
Plekhm2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr4_+_108834601 0.053 ENSMUST00000030296.8
Txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr1_-_74600564 0.044 ENSMUST00000127938.1
ENSMUST00000154874.1
Rnf25

ring finger protein 25

chrM_+_7759 0.028 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr15_-_58933688 0.023 ENSMUST00000110155.1
Tatdn1
TatD DNase domain containing 1
chr17_-_25785324 0.021 ENSMUST00000150324.1
Haghl
hydroxyacylglutathione hydrolase-like
chr11_+_113684412 0.008 ENSMUST00000042227.8
ENSMUST00000123466.1
ENSMUST00000106621.3
D11Wsu47e


DNA segment, Chr 11, Wayne State University 47, expressed



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0021759 globus pallidus development(GO:0021759)
1.4 4.1 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
1.1 7.9 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.8 2.3 GO:0036292 DNA rewinding(GO:0036292)
0.8 3.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.7 2.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.7 2.7 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.6 1.9 GO:0021557 oculomotor nerve development(GO:0021557) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.6 1.7 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.5 2.1 GO:0002339 B cell selection(GO:0002339)
0.5 1.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.4 1.3 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.4 1.2 GO:1903225 regulation of endodermal cell fate specification(GO:0042663) negative regulation of endodermal cell differentiation(GO:1903225)
0.4 1.4 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.3 1.0 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.3 4.8 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.3 1.6 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.3 3.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.3 1.8 GO:0002934 desmosome organization(GO:0002934)
0.3 4.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.3 2.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 1.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 1.2 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.2 1.0 GO:2000065 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.2 0.6 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.2 1.3 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.2 0.9 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 1.0 GO:0042940 D-amino acid transport(GO:0042940)
0.1 3.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 1.2 GO:0060539 diaphragm development(GO:0060539)
0.1 0.8 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 1.6 GO:0032060 bleb assembly(GO:0032060)
0.1 1.5 GO:0055070 copper ion homeostasis(GO:0055070)
0.1 0.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.2 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.1 2.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 2.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.4 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.2 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.5 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.0 1.2 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.2 GO:0019249 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0 1.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.8 GO:0007588 excretion(GO:0007588)
0.0 0.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.8 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.1 GO:1903525 regulation of membrane tubulation(GO:1903525)
0.0 0.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.3 4.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 2.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.8 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 2.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 6.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.1 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 4.2 GO:0005844 polysome(GO:0005844)
0.1 1.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 2.3 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 2.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 12.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.0 GO:0097440 apical dendrite(GO:0097440)
0.0 2.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 1.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 1.6 GO:0005901 caveola(GO:0005901)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 4.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 2.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.6 6.5 GO:0042301 phosphate ion binding(GO:0042301)
0.6 7.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.4 1.7 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.4 1.2 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.3 2.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.3 1.8 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.2 2.1 GO:0015643 toxic substance binding(GO:0015643)
0.2 1.5 GO:0001515 opioid peptide activity(GO:0001515)
0.2 2.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 0.8 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 4.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 7.9 GO:0043027 Ran GTPase binding(GO:0008536) cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 2.3 GO:0036310 annealing helicase activity(GO:0036310)
0.2 1.6 GO:0034711 inhibin binding(GO:0034711)
0.1 2.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 2.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 3.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.3 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.1 1.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 1.9 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 2.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 2.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.0 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.8 GO:0070402 NADPH binding(GO:0070402)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 2.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.5 GO:0005507 copper ion binding(GO:0005507)
0.0 1.8 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 1.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 2.4 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 2.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.9 GO:0051018 protein kinase A binding(GO:0051018)
0.0 12.5 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.2 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.9 GO:0019843 rRNA binding(GO:0019843)
0.0 2.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 3.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)