Motif ID: Nr1h4

Z-value: 0.914


Transcription factors associated with Nr1h4:

Gene SymbolEntrez IDGene Name
Nr1h4 ENSMUSG00000047638.9 Nr1h4



Activity profile for motif Nr1h4.

activity profile for motif Nr1h4


Sorted Z-values histogram for motif Nr1h4

Sorted Z-values for motif Nr1h4



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1h4

PNG image of the network

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Top targets:


Showing 1 to 20 of 133 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_50752758 8.828 ENSMUST00000034562.7
 Cryab
crystallin, alpha B
chr8_+_94179089 8.610 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr14_-_26170283 6.362 ENSMUST00000100809.4
 Plac9b
placenta specific 9b
chr7_-_31055594 5.780 ENSMUST00000039909.6
 Fxyd1
FXYD domain-containing ion transport regulator 1
chr10_+_13966268 5.750 ENSMUST00000015645.4
 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr1_+_172341197 5.719 ENSMUST00000056136.3
 Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr4_+_42916647 5.341 ENSMUST00000132173.1
ENSMUST00000107975.1
 N28178

expressed sequence N28178

chr9_+_44107268 5.176 ENSMUST00000114821.2
ENSMUST00000114818.2
 C1qtnf5

C1q and tumor necrosis factor related protein 5

chr7_-_105482197 5.066 ENSMUST00000047040.2
 Prkcdbp
protein kinase C, delta binding protein
chr9_+_44107286 5.064 ENSMUST00000152956.1
ENSMUST00000114815.1
 C1qtnf5

C1q and tumor necrosis factor related protein 5

chr19_+_4594312 4.859 ENSMUST00000113825.2
 Pcx
pyruvate carboxylase
chr14_-_30923754 4.641 ENSMUST00000006697.8
 Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr4_+_42917234 4.408 ENSMUST00000107976.2
ENSMUST00000069184.2
 N28178

expressed sequence N28178

chr14_-_30923547 4.266 ENSMUST00000170415.1
 Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr7_-_44670820 4.180 ENSMUST00000048102.7
 Myh14
myosin, heavy polypeptide 14
chr2_-_152951547 4.011 ENSMUST00000037715.6
 Dusp15
dual specificity phosphatase-like 15
chr9_+_54538984 3.866 ENSMUST00000060242.5
ENSMUST00000118413.1
 Sh2d7

SH2 domain containing 7

chr7_+_16310412 3.863 ENSMUST00000136781.1
 Bbc3
BCL2 binding component 3
chr1_-_162859684 3.821 ENSMUST00000131058.1
 Fmo1
flavin containing monooxygenase 1
chr4_+_53440388 3.805 ENSMUST00000102911.3
ENSMUST00000107646.2
 Slc44a1

solute carrier family 44, member 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 13.5 GO:0070206 protein trimerization(GO:0070206)
0.3 8.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
1.5 8.8 GO:0007021 tubulin complex assembly(GO:0007021)
1.2 8.6 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
0.1 7.6 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 7.4 GO:0046330 positive regulation of JNK cascade(GO:0046330)
1.6 6.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
1.9 5.8 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
0.0 5.8 GO:0010977 negative regulation of neuron projection development(GO:0010977)
1.9 5.7 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.9 5.7 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
1.7 5.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
1.7 5.1 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
1.6 4.9 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 4.2 GO:0071625 vocalization behavior(GO:0071625)
1.0 3.9 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.8 3.8 GO:0015871 choline transport(GO:0015871)
0.4 3.8 GO:0009404 toxin metabolic process(GO:0009404)
0.3 3.7 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
1.1 3.4 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 8.8 GO:0097512 cardiac myofibril(GO:0097512)
0.2 8.5 GO:0034707 chloride channel complex(GO:0034707)
0.1 7.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 7.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 7.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 6.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.5 5.7 GO:0097449 astrocyte projection(GO:0097449)
0.0 5.6 GO:0098793 presynapse(GO:0098793)
0.0 5.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 5.1 GO:0005901 caveola(GO:0005901)
0.0 5.1 GO:0031965 nuclear membrane(GO:0031965)
0.7 4.2 GO:0097513 myosin II filament(GO:0097513)
0.7 3.4 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 3.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 3.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.0 GO:0005770 late endosome(GO:0005770)
0.1 2.9 GO:0009925 basal plasma membrane(GO:0009925)
0.5 2.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 2.7 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.4 GO:0010008 endosome membrane(GO:0010008)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 8.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.0 8.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 8.6 GO:0005507 copper ion binding(GO:0005507)
0.1 7.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 6.4 GO:0005254 chloride channel activity(GO:0005254)
1.1 6.3 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
1.9 5.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.4 5.7 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 5.2 GO:0005080 protein kinase C binding(GO:0005080)
0.8 5.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.8 4.9 GO:0009374 biotin binding(GO:0009374)
0.1 3.9 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 3.9 GO:0051117 ATPase binding(GO:0051117)
1.0 3.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.8 3.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.7 3.7 GO:0034235 GPI anchor binding(GO:0034235)
0.1 3.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 3.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 3.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)