Motif ID: Nr1i3

Z-value: 1.640


Transcription factors associated with Nr1i3:

Gene SymbolEntrez IDGene Name
Nr1i3 ENSMUSG00000005677.8 Nr1i3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr1i3mm10_v2_chr1_+_171213969_171214007-0.085.7e-01Click!


Activity profile for motif Nr1i3.

activity profile for motif Nr1i3


Sorted Z-values histogram for motif Nr1i3

Sorted Z-values for motif Nr1i3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1i3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_166254095 12.095 ENSMUST00000111416.1
 Ildr2
immunoglobulin-like domain containing receptor 2
chr11_+_32276400 11.531 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr4_-_137785371 9.342 ENSMUST00000133473.1
 Alpl
alkaline phosphatase, liver/bone/kidney
chr9_+_65630552 8.729 ENSMUST00000055844.8
 Rbpms2
RNA binding protein with multiple splicing 2
chr5_-_116422858 8.504 ENSMUST00000036991.4
 Hspb8
heat shock protein 8
chr1_-_163289214 8.028 ENSMUST00000183691.1
 Prrx1
paired related homeobox 1
chr1_+_135729147 7.419 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr1_+_87264345 7.174 ENSMUST00000118687.1
ENSMUST00000027472.6
 Efhd1

EF hand domain containing 1

chr9_-_30922452 7.167 ENSMUST00000065112.6
 Adamts15
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
chr11_-_3931960 6.912 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
 Tcn2




transcobalamin 2




chr17_+_47505117 6.861 ENSMUST00000183044.1
ENSMUST00000037333.10
 Ccnd3

cyclin D3

chr4_-_148087961 6.516 ENSMUST00000030865.8
 Agtrap
angiotensin II, type I receptor-associated protein
chr7_-_103843154 6.499 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr14_-_48667508 6.492 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
 Otx2



orthodenticle homolog 2 (Drosophila)



chr9_-_27155418 6.087 ENSMUST00000167074.1
ENSMUST00000034472.8
 Jam3

junction adhesion molecule 3

chr17_-_58991343 5.859 ENSMUST00000025064.7
 2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr2_+_122147680 5.706 ENSMUST00000102476.4
 B2m
beta-2 microglobulin
chr7_-_30973464 5.549 ENSMUST00000001279.8
 Lsr
lipolysis stimulated lipoprotein receptor
chr2_+_30078584 5.525 ENSMUST00000045246.7
 Pkn3
protein kinase N3
chr10_-_35711891 5.506 ENSMUST00000080898.2
 Amd2
S-adenosylmethionine decarboxylase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 683 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 23.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
3.6 18.0 GO:0015671 oxygen transport(GO:0015671)
0.4 16.7 GO:0070206 protein trimerization(GO:0070206)
1.0 16.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
5.2 15.7 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.4 14.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.3 14.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.4 11.8 GO:0046677 response to antibiotic(GO:0046677)
0.3 11.5 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.6 11.0 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.5 10.5 GO:0038092 nodal signaling pathway(GO:0038092)
3.5 10.4 GO:0015889 cobalamin transport(GO:0015889)
1.7 10.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
1.0 9.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.8 9.0 GO:0060539 diaphragm development(GO:0060539)
0.1 8.8 GO:0051028 mRNA transport(GO:0051028)
1.4 8.3 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
1.4 8.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.6 8.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.9 8.0 GO:0048664 neuron fate determination(GO:0048664)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 276 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 52.5 GO:0005667 transcription factor complex(GO:0005667)
0.2 37.5 GO:0031012 extracellular matrix(GO:0031012)
0.1 27.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.6 26.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 21.9 GO:0005615 extracellular space(GO:0005615)
0.4 19.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 18.5 GO:0000922 spindle pole(GO:0000922)
2.3 18.0 GO:0005833 hemoglobin complex(GO:0005833)
0.1 18.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 17.0 GO:0005657 replication fork(GO:0005657)
0.2 15.9 GO:0005604 basement membrane(GO:0005604)
2.6 15.7 GO:0061689 tricellular tight junction(GO:0061689)
0.1 15.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 15.1 GO:0015934 large ribosomal subunit(GO:0015934)
0.9 14.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 14.3 GO:0005925 focal adhesion(GO:0005925)
0.9 13.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.2 13.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 12.8 GO:0005740 mitochondrial envelope(GO:0005740)
0.3 12.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 435 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 27.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.6 25.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.5 23.7 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.7 22.2 GO:0071837 HMG box domain binding(GO:0071837)
3.6 18.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.9 15.7 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
1.0 14.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.7 13.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 13.3 GO:0005178 integrin binding(GO:0005178)
3.1 12.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.8 12.0 GO:0008430 selenium binding(GO:0008430)
0.3 11.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 11.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.5 10.8 GO:0031419 cobalamin binding(GO:0031419)
0.5 10.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.7 10.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.6 10.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.3 9.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 9.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 9.5 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)