Motif ID: Nr2c1

Z-value: 0.647


Transcription factors associated with Nr2c1:

Gene SymbolEntrez IDGene Name
Nr2c1 ENSMUSG00000005897.8 Nr2c1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c1mm10_v2_chr10_+_94147982_94148023-0.113.9e-01Click!


Activity profile for motif Nr2c1.

activity profile for motif Nr2c1


Sorted Z-values histogram for motif Nr2c1

Sorted Z-values for motif Nr2c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c1

PNG image of the network

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Top targets:


Showing 1 to 20 of 104 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_29411736 4.783 ENSMUST00000115236.1
 Ntm
neurotrimin
chr4_-_46991842 4.759 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr10_+_58813359 4.302 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr7_+_110768169 4.279 ENSMUST00000170374.1
 Ampd3
adenosine monophosphate deaminase 3
chr9_-_29412204 4.193 ENSMUST00000115237.1
 Ntm
neurotrimin
chr15_+_80091320 4.084 ENSMUST00000009728.6
ENSMUST00000009727.5
 Syngr1

synaptogyrin 1

chr2_-_29253001 3.554 ENSMUST00000071201.4
 Ntng2
netrin G2
chr1_-_155417283 3.262 ENSMUST00000027741.5
 Xpr1
xenotropic and polytropic retrovirus receptor 1
chr12_-_83487708 3.182 ENSMUST00000177959.1
ENSMUST00000178756.1
 Dpf3

D4, zinc and double PHD fingers, family 3

chr7_+_46397648 3.125 ENSMUST00000160433.1
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr6_+_22875496 3.083 ENSMUST00000090568.3
 Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chrX_+_10485121 2.900 ENSMUST00000076354.6
ENSMUST00000115526.1
 Tspan7

tetraspanin 7

chr11_-_3504766 2.795 ENSMUST00000044507.5
 Inpp5j
inositol polyphosphate 5-phosphatase J
chr15_+_81811414 2.734 ENSMUST00000023024.7
 Tef
thyrotroph embryonic factor
chr15_+_3270767 2.695 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr9_-_21037775 2.570 ENSMUST00000180870.1
 Gm26592
predicted gene, 26592
chr11_-_26210553 2.496 ENSMUST00000101447.3
 5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr10_+_93589413 2.475 ENSMUST00000181835.1
 4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr4_+_133039482 2.284 ENSMUST00000105914.1
 Ahdc1
AT hook, DNA binding motif, containing 1
chr5_+_117120120 2.140 ENSMUST00000111978.1
 Taok3
TAO kinase 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.1 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.2 4.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.5 4.3 GO:0032264 IMP salvage(GO:0032264)
0.2 4.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.2 3.6 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.5 3.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 3.2 GO:0098792 xenophagy(GO:0098792)
1.0 3.1 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.1 3.1 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.1 2.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.4 2.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 2.6 GO:0048511 rhythmic process(GO:0048511)
0.5 2.4 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 2.4 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 2.2 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.1 2.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 2.0 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.2 1.9 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 1.9 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.4 1.8 GO:0019372 lipoxygenase pathway(GO:0019372)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.0 GO:0031225 anchored component of membrane(GO:0031225)
0.1 6.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 5.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
1.0 4.8 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.6 3.6 GO:0097427 microtubule bundle(GO:0097427)
0.1 3.2 GO:0071565 nBAF complex(GO:0071565)
1.0 3.1 GO:0072534 perineuronal net(GO:0072534)
0.1 3.1 GO:0030673 axolemma(GO:0030673)
0.0 2.8 GO:0043198 dendritic shaft(GO:0043198)
0.1 2.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 2.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.9 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 4.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.6 4.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 4.2 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 3.5 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.4 3.3 GO:0001618 virus receptor activity(GO:0001618)
0.1 3.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 3.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.9 2.8 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.2 2.7 GO:0008430 selenium binding(GO:0008430)
0.2 2.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.6 2.4 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 2.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 2.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 1.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 1.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.6 GO:0005496 steroid binding(GO:0005496)
0.3 1.4 GO:0004103 choline kinase activity(GO:0004103)
0.1 1.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 1.0 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)