Motif ID: Nr2e1

Z-value: 0.319


Transcription factors associated with Nr2e1:

Gene SymbolEntrez IDGene Name
Nr2e1 ENSMUSG00000019803.5 Nr2e1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2e1mm10_v2_chr10_-_42583628_425836390.029.0e-01Click!


Activity profile for motif Nr2e1.

activity profile for motif Nr2e1


Sorted Z-values histogram for motif Nr2e1

Sorted Z-values for motif Nr2e1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2e1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_33924632 2.771 ENSMUST00000057188.6
Cnr1
cannabinoid receptor 1 (brain)
chr14_+_32028989 1.583 ENSMUST00000022460.4
Galnt15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr3_+_26331150 1.029 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr4_+_32238950 0.976 ENSMUST00000037416.6
Bach2
BTB and CNC homology 2
chr2_-_73386396 0.907 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
Gpr155


G protein-coupled receptor 155


chr8_+_36489191 0.588 ENSMUST00000171777.1
6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr7_-_80405425 0.467 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr3_-_146781351 0.455 ENSMUST00000005164.7
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chrX_-_95658379 0.381 ENSMUST00000119640.1
Zc4h2
zinc finger, C4H2 domain containing
chr9_-_58158498 0.378 ENSMUST00000168864.2
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr18_+_34840575 0.366 ENSMUST00000043484.7
Reep2
receptor accessory protein 2
chr10_+_18469958 0.339 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr9_-_71163224 0.277 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr15_+_41830921 0.267 ENSMUST00000166917.1
Oxr1
oxidation resistance 1
chr2_-_23040137 0.265 ENSMUST00000091394.6
ENSMUST00000093171.6
Abi1

abl-interactor 1

chrX_-_95658416 0.261 ENSMUST00000044382.6
Zc4h2
zinc finger, C4H2 domain containing
chrX_-_95658392 0.260 ENSMUST00000120620.1
Zc4h2
zinc finger, C4H2 domain containing
chr2_-_23040177 0.248 ENSMUST00000114544.3
ENSMUST00000139038.1
ENSMUST00000126112.1
ENSMUST00000178908.1
ENSMUST00000078977.7
ENSMUST00000140164.1
ENSMUST00000149719.1
Abi1






abl-interactor 1






chr1_-_132390301 0.217 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chrX_-_139998519 0.217 ENSMUST00000113007.1
ENSMUST00000033810.7
ENSMUST00000113011.2
ENSMUST00000087400.5
Rbm41



RNA binding motif protein 41



chr9_-_42457594 0.202 ENSMUST00000125995.1
Tbcel
tubulin folding cofactor E-like
chr4_-_63403330 0.195 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr2_-_23040092 0.175 ENSMUST00000153931.1
ENSMUST00000123948.1
Abi1

abl-interactor 1

chr1_-_53785214 0.168 ENSMUST00000027263.7
Stk17b
serine/threonine kinase 17b (apoptosis-inducing)
chr6_+_126939957 0.163 ENSMUST00000032497.3
D6Wsu163e
DNA segment, Chr 6, Wayne State University 163, expressed
chr1_+_24678536 0.160 ENSMUST00000095062.3
Lmbrd1
LMBR1 domain containing 1
chr17_+_33919332 0.144 ENSMUST00000025161.7
Tapbp
TAP binding protein
chr4_-_35845204 0.128 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr5_-_88527841 0.107 ENSMUST00000087033.3
Igj
immunoglobulin joining chain
chr4_+_28813125 0.105 ENSMUST00000029964.5
ENSMUST00000080934.4
Epha7

Eph receptor A7

chr7_+_78895903 0.068 ENSMUST00000107425.1
ENSMUST00000107421.1
ENSMUST00000107423.1
Aen


apoptosis enhancing nuclease


chr4_+_28813152 0.058 ENSMUST00000108194.2
ENSMUST00000108191.1
Epha7

Eph receptor A7

chr12_+_111166485 0.025 ENSMUST00000139162.1
Traf3
TNF receptor-associated factor 3
chr12_+_111166349 0.016 ENSMUST00000117269.1
Traf3
TNF receptor-associated factor 3
chr12_-_87147883 0.010 ENSMUST00000037788.4
Pomt2
protein-O-mannosyltransferase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0031622 positive regulation of fever generation(GO:0031622)
0.1 0.5 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.4 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.3 GO:0032782 urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.6 GO:0030426 growth cone(GO:0030426)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0015265 urea channel activity(GO:0015265)
0.0 0.1 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 2.8 GO:0008144 drug binding(GO:0008144)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)