Motif ID: Nr3c2

Z-value: 0.616


Transcription factors associated with Nr3c2:

Gene SymbolEntrez IDGene Name
Nr3c2 ENSMUSG00000031618.7 Nr3c2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c2mm10_v2_chr8_+_76902277_76902476-0.444.3e-04Click!


Activity profile for motif Nr3c2.

activity profile for motif Nr3c2


Sorted Z-values histogram for motif Nr3c2

Sorted Z-values for motif Nr3c2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr3c2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_95904683 6.383 ENSMUST00000147962.1
ENSMUST00000036181.8
 Car14

carbonic anhydrase 14

chr9_+_123366921 5.101 ENSMUST00000038863.7
 Lars2
leucyl-tRNA synthetase, mitochondrial
chr4_-_149137536 4.992 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
 Apitd1



apoptosis-inducing, TAF9-like domain 1



chr13_+_99100698 4.144 ENSMUST00000181742.1
 Gm807
predicted gene 807
chr15_-_97020322 3.941 ENSMUST00000166223.1
 Slc38a4
solute carrier family 38, member 4
chr5_-_31697598 2.954 ENSMUST00000031018.7
 Rbks
ribokinase
chr14_-_8309770 2.792 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
 Fam107a


family with sequence similarity 107, member A


chr10_+_128225830 2.641 ENSMUST00000026455.7
 Mip
major intrinsic protein of eye lens fiber
chr4_-_9643638 2.637 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
 Asph




aspartate-beta-hydroxylase




chr14_+_70530819 2.508 ENSMUST00000047331.6
 Lgi3
leucine-rich repeat LGI family, member 3
chr10_+_26822560 2.167 ENSMUST00000135866.1
 Arhgap18
Rho GTPase activating protein 18
chr10_-_78464853 2.163 ENSMUST00000105385.1
 Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr10_-_78464969 2.018 ENSMUST00000041616.8
 Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr1_-_171240055 1.966 ENSMUST00000131286.1
 Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr8_+_71406003 1.738 ENSMUST00000119976.1
ENSMUST00000120725.1
 Ankle1

ankyrin repeat and LEM domain containing 1

chr8_+_94179089 1.545 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr2_+_172472512 1.462 ENSMUST00000029007.2
 Fam209
family with sequence similarity 209
chr15_+_102102926 1.451 ENSMUST00000169627.1
ENSMUST00000046144.9
 Tenc1

tensin like C1 domain-containing phosphatase

chr6_-_6882068 1.425 ENSMUST00000142635.1
ENSMUST00000052609.8
 Dlx5

distal-less homeobox 5

chr1_-_74935549 1.283 ENSMUST00000094844.3
 Ccdc108
coiled-coil domain containing 108
chr14_+_66784523 0.985 ENSMUST00000071522.2
 Gm10032
predicted gene 10032
chr3_-_88739692 0.771 ENSMUST00000090946.2
 Gm10253
predicted gene 10253
chr6_-_69400097 0.741 ENSMUST00000177795.1
 Igkv4-62
immunoglobulin kappa variable 4-62
chr6_-_69631933 0.663 ENSMUST00000177697.1
 Igkv4-54
immunoglobulin kappa chain variable 4-54
chr11_+_101448403 0.628 ENSMUST00000010502.6
 Ifi35
interferon-induced protein 35
chr5_+_31697665 0.432 ENSMUST00000080598.7
 Bre
brain and reproductive organ-expressed protein
chr16_-_96192222 0.363 ENSMUST00000113804.1
ENSMUST00000054855.7
 Lca5l

Leber congenital amaurosis 5-like

chr10_-_117282262 0.249 ENSMUST00000092163.7
 Lyz2
lysozyme 2
chr2_-_91444622 0.224 ENSMUST00000064652.7
ENSMUST00000102594.4
ENSMUST00000094835.2
 1110051M20Rik


RIKEN cDNA 1110051M20 gene


chr10_-_14718191 0.132 ENSMUST00000020016.4
 Gje1
gap junction protein, epsilon 1
chr15_-_82047579 0.093 ENSMUST00000166578.1
ENSMUST00000080622.7
 Nhp2l1

NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0042822 vitamin B6 metabolic process(GO:0042816) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.9 2.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.8 6.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.6 5.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.5 1.4 GO:0060166 olfactory pit development(GO:0060166)
0.4 3.0 GO:0019321 pentose metabolic process(GO:0019321)
0.4 2.6 GO:0032782 cellular water homeostasis(GO:0009992) bile acid secretion(GO:0032782)
0.2 1.5 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
0.1 3.9 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 5.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 1.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 2.5 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.2 GO:0019835 cytolysis(GO:0019835)
0.0 0.4 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 2.2 GO:0008360 regulation of cell shape(GO:0008360)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.5 2.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.8 GO:0005921 gap junction(GO:0005921)
0.1 0.4 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 2.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 2.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0031403 lithium ion binding(GO:0031403)
0.5 6.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 2.6 GO:0015168 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.2 5.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 2.0 GO:0048038 quinone binding(GO:0048038)
0.1 3.0 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 1.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 3.9 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 2.6 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.1 GO:0034511 U4 snRNA binding(GO:0030621) U3 snoRNA binding(GO:0034511)
0.0 0.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)