Motif ID: Nr4a2
Z-value: 0.532
Transcription factors associated with Nr4a2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr4a2 | ENSMUSG00000026826.7 | Nr4a2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr4a2 | mm10_v2_chr2_-_57124003_57124071 | 0.21 | 1.1e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.1 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.7 | 2.9 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
0.6 | 1.9 | GO:0019405 | alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
0.6 | 2.9 | GO:0021905 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) |
0.6 | 1.8 | GO:0030210 | heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014) |
0.5 | 1.6 | GO:0046544 | regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544) |
0.3 | 1.7 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
0.2 | 1.9 | GO:1903624 | regulation of apoptotic DNA fragmentation(GO:1902510) regulation of DNA catabolic process(GO:1903624) |
0.2 | 0.7 | GO:0035811 | negative regulation of urine volume(GO:0035811) |
0.2 | 1.8 | GO:0002681 | somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153) |
0.2 | 1.7 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.2 | 0.9 | GO:0014719 | skeletal muscle satellite cell activation(GO:0014719) |
0.2 | 1.1 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
0.2 | 1.2 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.1 | 1.3 | GO:0032306 | regulation of prostaglandin secretion(GO:0032306) embryonic process involved in female pregnancy(GO:0060136) |
0.1 | 0.5 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.1 | 1.0 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.1 | 0.2 | GO:0032714 | negative regulation of interleukin-5 production(GO:0032714) |
0.1 | 0.8 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.1 | 2.0 | GO:0010107 | potassium ion import(GO:0010107) |
0.1 | 0.5 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.1 | 0.9 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
0.1 | 0.7 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.1 | 0.4 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
0.1 | 0.8 | GO:0046628 | positive regulation of insulin receptor signaling pathway(GO:0046628) |
0.0 | 0.3 | GO:0045072 | regulation of interferon-gamma biosynthetic process(GO:0045072) |
0.0 | 4.1 | GO:0006096 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
0.0 | 1.0 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
0.0 | 0.6 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
0.0 | 0.5 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
0.0 | 1.2 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
0.0 | 1.1 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.0 | 1.0 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.0 | 0.5 | GO:0071470 | cellular response to osmotic stress(GO:0071470) |
0.0 | 0.1 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.0 | 1.9 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.0 | 0.8 | GO:0006284 | base-excision repair(GO:0006284) |
0.0 | 0.6 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.3 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.0 | 0.6 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
0.0 | 0.9 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
0.0 | 0.5 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 1.3 | GO:0043507 | positive regulation of JUN kinase activity(GO:0043507) |
0.0 | 0.3 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 0.8 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
0.0 | 0.6 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
0.0 | 0.6 | GO:0015909 | long-chain fatty acid transport(GO:0015909) |
0.0 | 0.1 | GO:0007602 | phototransduction(GO:0007602) |
0.0 | 0.3 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 4.1 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.6 | 1.7 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.4 | 2.9 | GO:0042627 | chylomicron(GO:0042627) |
0.4 | 1.1 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
0.3 | 2.8 | GO:0031415 | NatA complex(GO:0031415) |
0.2 | 1.3 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.1 | 0.5 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.1 | 1.2 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.1 | 0.4 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.1 | 0.3 | GO:0034715 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
0.0 | 0.7 | GO:0031528 | microvillus membrane(GO:0031528) |
0.0 | 1.8 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.0 | 0.5 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 2.7 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 0.6 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
0.0 | 0.9 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.5 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 0.4 | GO:0016460 | myosin II complex(GO:0016460) |
0.0 | 1.9 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.0 | 2.0 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 0.8 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.9 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.1 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.0 | 0.5 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.0 | 1.5 | GO:0005930 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
0.0 | 1.0 | GO:0016528 | sarcoplasm(GO:0016528) |
0.0 | 0.6 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.6 | GO:0031968 | mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968) |
0.0 | 0.3 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 3.1 | GO:0019808 | polyamine binding(GO:0019808) |
0.6 | 1.9 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
0.5 | 4.1 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.4 | 2.0 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.3 | 1.7 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
0.3 | 0.8 | GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
0.3 | 1.1 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.3 | 2.9 | GO:0003680 | AT DNA binding(GO:0003680) |
0.3 | 2.9 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.3 | 1.3 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.2 | 1.7 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.2 | 1.9 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.2 | 1.1 | GO:0001515 | opioid peptide activity(GO:0001515) |
0.1 | 1.1 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.1 | 1.8 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
0.1 | 0.8 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.1 | 1.3 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.1 | 0.5 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
0.1 | 0.6 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
0.1 | 0.7 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.1 | 1.0 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.1 | 0.5 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.1 | 1.0 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.1 | 0.2 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
0.1 | 1.2 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.1 | 1.6 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 1.1 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 2.5 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.2 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.0 | 0.5 | GO:0035173 | histone kinase activity(GO:0035173) |
0.0 | 1.9 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
0.0 | 0.2 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
0.0 | 0.3 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 0.3 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.0 | 0.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 2.5 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.0 | 0.6 | GO:0004896 | cytokine receptor activity(GO:0004896) |
0.0 | 0.6 | GO:0030507 | spectrin binding(GO:0030507) |