Motif ID: Nr6a1

Z-value: 0.513


Transcription factors associated with Nr6a1:

Gene SymbolEntrez IDGene Name
Nr6a1 ENSMUSG00000063972.7 Nr6a1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr6a1mm10_v2_chr2_-_38926217_389264540.274.1e-02Click!


Activity profile for motif Nr6a1.

activity profile for motif Nr6a1


Sorted Z-values histogram for motif Nr6a1

Sorted Z-values for motif Nr6a1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr6a1

PNG image of the network

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Top targets:


Showing 1 to 20 of 70 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_66427469 2.807 ENSMUST00000015278.7
 Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
chr7_+_30314810 2.790 ENSMUST00000054594.8
ENSMUST00000177078.1
ENSMUST00000176504.1
ENSMUST00000176304.1
 Syne4



spectrin repeat containing, nuclear envelope family member 4



chr1_+_131970589 1.945 ENSMUST00000027695.6
 Slc45a3
solute carrier family 45, member 3
chr4_-_45530330 1.937 ENSMUST00000061986.5
 Shb
src homology 2 domain-containing transforming protein B
chr2_+_172472512 1.881 ENSMUST00000029007.2
 Fam209
family with sequence similarity 209
chr5_-_137610626 1.770 ENSMUST00000142675.1
 Pcolce
procollagen C-endopeptidase enhancer protein
chr13_-_24761440 1.595 ENSMUST00000176890.1
ENSMUST00000175689.1
 Gmnn

geminin

chr6_+_83349446 1.584 ENSMUST00000136501.1
 Bola3
bolA-like 3 (E. coli)
chr11_-_60811228 1.477 ENSMUST00000018744.8
 Shmt1
serine hydroxymethyltransferase 1 (soluble)
chr5_-_137611372 1.452 ENSMUST00000054564.6
 Pcolce
procollagen C-endopeptidase enhancer protein
chr12_+_3807017 1.442 ENSMUST00000020991.8
ENSMUST00000172509.1
 Dnmt3a

DNA methyltransferase 3A

chr10_+_128083273 1.387 ENSMUST00000026459.5
 Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr5_-_137611429 1.349 ENSMUST00000031731.7
 Pcolce
procollagen C-endopeptidase enhancer protein
chr9_+_50603892 1.336 ENSMUST00000044051.4
 Timm8b
translocase of inner mitochondrial membrane 8B
chr12_-_115790884 1.180 ENSMUST00000081809.5
 Ighv1-73
immunoglobulin heavy variable 1-73
chr12_+_3807076 1.177 ENSMUST00000174817.1
 Dnmt3a
DNA methyltransferase 3A
chr2_+_180071793 1.172 ENSMUST00000108901.1
 Mtg2
mitochondrial ribosome associated GTPase 2
chr9_-_96437434 1.154 ENSMUST00000070500.2
 BC043934
cDNA sequence BC043934
chr14_+_58072686 1.119 ENSMUST00000022545.7
 Fgf9
fibroblast growth factor 9
chr15_-_98165613 1.095 ENSMUST00000143400.1
 Asb8
ankyrin repeat and SOCS box-containing 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 2.8 GO:0060166 olfactory pit development(GO:0060166)
0.3 2.8 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3 2.6 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.8 2.5 GO:0009177 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.3 2.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.6 1.9 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 1.6 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.3 1.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 1.4 GO:0051225 spindle assembly(GO:0051225)
0.1 1.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.1 1.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 1.0 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.0 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 1.0 GO:0030317 sperm motility(GO:0030317)
0.2 0.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.9 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.9 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.1 0.9 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.9 GO:1901998 toxin transport(GO:1901998)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 2.6 GO:0001741 XY body(GO:0001741)
0.0 2.2 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 1.6 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.2 1.4 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.2 1.0 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.2 1.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.1 1.0 GO:0042555 MCM complex(GO:0042555)
0.2 0.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)
0.1 0.7 GO:0090543 Flemming body(GO:0090543)
0.0 0.5 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.4 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.2 GO:0005940 septin ring(GO:0005940)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.6 GO:0016504 peptidase activator activity(GO:0016504)
0.6 2.8 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.3 2.6 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 2.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.6 1.9 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 1.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.9 GO:0030792 methylarsonite methyltransferase activity(GO:0030792)
0.5 1.5 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) serine binding(GO:0070905)
0.1 1.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.0 GO:0005542 folic acid binding(GO:0005542)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.9 GO:0051087 chaperone binding(GO:0051087)
0.2 0.8 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.8 GO:0003777 microtubule motor activity(GO:0003777)
0.2 0.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 0.7 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.7 GO:0015035 glutathione peroxidase activity(GO:0004602) protein disulfide oxidoreductase activity(GO:0015035)