Motif ID: Olig2_Olig3

Z-value: 0.970

Transcription factors associated with Olig2_Olig3:

Gene SymbolEntrez IDGene Name
Olig2 ENSMUSG00000039830.8 Olig2
Olig3 ENSMUSG00000045591.5 Olig3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Olig3mm10_v2_chr10_+_19356558_193565650.364.9e-03Click!
Olig2mm10_v2_chr16_+_91225550_91225579-0.311.5e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Olig2_Olig3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_32276400 14.447 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr10_-_92164666 13.005 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr3_-_154330543 12.465 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr9_-_119825456 10.937 ENSMUST00000070617.7
Scn11a
sodium channel, voltage-gated, type XI, alpha
chr16_+_16213318 10.563 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
Pkp2


plakophilin 2


chr19_-_53589067 9.895 ENSMUST00000095978.3
Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr1_+_12692430 9.332 ENSMUST00000180062.1
ENSMUST00000177608.1
Sulf1

sulfatase 1

chr1_-_186117251 8.013 ENSMUST00000045388.7
Lyplal1
lysophospholipase-like 1
chr11_-_102365111 7.908 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr3_-_63851251 7.247 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr3_+_125404072 6.903 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr16_-_44558864 6.820 ENSMUST00000023370.4
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr1_+_51987139 6.732 ENSMUST00000168302.1
Stat4
signal transducer and activator of transcription 4
chr3_+_125404292 6.688 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr16_-_44558879 6.620 ENSMUST00000114634.1
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr5_+_92925400 6.565 ENSMUST00000172706.1
Shroom3
shroom family member 3
chr7_+_30314810 6.436 ENSMUST00000054594.8
ENSMUST00000177078.1
ENSMUST00000176504.1
ENSMUST00000176304.1
Syne4



spectrin repeat containing, nuclear envelope family member 4



chr11_-_69920892 6.055 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr10_+_45067167 5.990 ENSMUST00000099858.2
Prep
prolyl endopeptidase
chr17_-_62606679 5.945 ENSMUST00000163332.1
Efna5
ephrin A5

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 153 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 14.4 GO:0015671 oxygen transport(GO:0015671)
0.2 12.2 GO:0032526 response to retinoic acid(GO:0032526)
1.9 11.6 GO:0032796 uropod organization(GO:0032796)
3.5 10.6 GO:0002159 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496)
0.4 10.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
2.3 9.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.4 8.6 GO:0014823 response to activity(GO:0014823)
1.6 8.0 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.2 7.8 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
1.2 7.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 7.0 GO:0006412 translation(GO:0006412)
0.1 6.8 GO:0007405 neuroblast proliferation(GO:0007405)
0.6 6.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.6 5.7 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 5.7 GO:0021884 forebrain neuron development(GO:0021884)
1.4 5.5 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.6 5.5 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.3 5.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 5.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 4.8 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 90 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 16.3 GO:0070161 adherens junction(GO:0005912) anchoring junction(GO:0070161)
1.8 14.4 GO:0005833 hemoglobin complex(GO:0005833)
0.3 13.4 GO:0044295 axonal growth cone(GO:0044295)
1.1 12.8 GO:0030057 desmosome(GO:0030057)
2.1 12.5 GO:0001674 female germ cell nucleus(GO:0001674)
0.5 12.3 GO:0001891 phagocytic cup(GO:0001891)
3.6 10.9 GO:0044299 C-fiber(GO:0044299)
0.1 8.6 GO:0072562 blood microparticle(GO:0072562)
0.7 7.3 GO:0005642 annulate lamellae(GO:0005642)
0.6 6.8 GO:1990023 mitotic spindle midzone(GO:1990023)
0.7 6.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.6 5.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 5.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 5.0 GO:0000790 nuclear chromatin(GO:0000790)
0.7 4.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 4.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4 4.3 GO:0001739 sex chromatin(GO:0001739)
0.4 3.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 3.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.6 3.4 GO:0030896 checkpoint clamp complex(GO:0030896)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 125 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 14.4 GO:0005344 oxygen transporter activity(GO:0005344)
1.9 13.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 12.9 GO:0003735 structural constituent of ribosome(GO:0003735)
1.2 11.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.9 10.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 9.4 GO:0008270 zinc ion binding(GO:0008270)
1.9 9.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.8 8.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.5 7.9 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.6 7.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.4 7.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 6.0 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 5.9 GO:0051015 actin filament binding(GO:0051015)
0.9 5.5 GO:0008494 translation activator activity(GO:0008494)
0.9 5.5 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 5.5 GO:0003714 transcription corepressor activity(GO:0003714)
1.4 5.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.7 5.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 4.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.3 4.6 GO:0031005 filamin binding(GO:0031005)