Motif ID: Osr2_Osr1
Z-value: 0.810
Transcription factors associated with Osr2_Osr1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Osr1 | ENSMUSG00000048387.7 | Osr1 |
Osr2 | ENSMUSG00000022330.4 | Osr2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Osr1 | mm10_v2_chr12_+_9574437_9574448 | 0.00 | 9.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.7 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
0.4 | 1.3 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) |
0.4 | 1.3 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) glutamate secretion, neurotransmission(GO:0061535) |
0.4 | 3.3 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.4 | 1.2 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
0.4 | 6.5 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.3 | 3.0 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
0.3 | 1.0 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
0.3 | 2.0 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.2 | 0.7 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
0.2 | 1.3 | GO:0051013 | microtubule severing(GO:0051013) |
0.2 | 1.0 | GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
0.2 | 0.8 | GO:0033499 | galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623) |
0.2 | 3.8 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
0.1 | 0.4 | GO:0070375 | ERK5 cascade(GO:0070375) |
0.1 | 9.4 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
0.1 | 0.8 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
0.1 | 0.5 | GO:0007228 | positive regulation of hh target transcription factor activity(GO:0007228) |
0.1 | 0.7 | GO:0038026 | glycoprotein transport(GO:0034436) reelin-mediated signaling pathway(GO:0038026) |
0.1 | 0.3 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
0.1 | 1.1 | GO:0006537 | glutamate biosynthetic process(GO:0006537) proline biosynthetic process(GO:0006561) |
0.1 | 1.0 | GO:2000809 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809) |
0.1 | 1.8 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
0.1 | 1.2 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.1 | 4.2 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
0.1 | 1.1 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
0.1 | 0.5 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
0.1 | 0.9 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.1 | 0.3 | GO:0030576 | Cajal body organization(GO:0030576) |
0.1 | 0.7 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.1 | 2.1 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) innervation(GO:0060384) |
0.1 | 1.4 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
0.1 | 0.2 | GO:0042420 | dopamine catabolic process(GO:0042420) |
0.1 | 0.5 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.1 | 0.3 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
0.1 | 0.8 | GO:0051601 | exocyst localization(GO:0051601) |
0.1 | 0.7 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
0.1 | 2.8 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
0.1 | 1.6 | GO:0010842 | retina layer formation(GO:0010842) |
0.1 | 0.4 | GO:0015862 | uridine transport(GO:0015862) |
0.0 | 0.3 | GO:0036112 | medium-chain fatty-acyl-CoA metabolic process(GO:0036112) |
0.0 | 0.6 | GO:0045217 | cell-cell junction maintenance(GO:0045217) |
0.0 | 0.3 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
0.0 | 1.2 | GO:0009303 | rRNA transcription(GO:0009303) |
0.0 | 1.1 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
0.0 | 0.7 | GO:0030813 | positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) |
0.0 | 0.3 | GO:0009992 | cellular water homeostasis(GO:0009992) |
0.0 | 1.2 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
0.0 | 0.4 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
0.0 | 0.3 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
0.0 | 1.8 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
0.0 | 2.1 | GO:0051897 | positive regulation of protein kinase B signaling(GO:0051897) |
0.0 | 0.4 | GO:0044065 | regulation of respiratory system process(GO:0044065) |
0.0 | 2.1 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.0 | 0.6 | GO:0010107 | potassium ion import(GO:0010107) |
0.0 | 0.9 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
0.0 | 0.7 | GO:0030488 | tRNA methylation(GO:0030488) |
0.0 | 0.1 | GO:0000393 | spliceosomal conformational changes to generate catalytic conformation(GO:0000393) |
0.0 | 0.4 | GO:0060259 | regulation of feeding behavior(GO:0060259) |
0.0 | 0.5 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
0.0 | 0.3 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
0.0 | 0.3 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.4 | GO:0006878 | cellular copper ion homeostasis(GO:0006878) |
0.0 | 0.2 | GO:0045351 | type I interferon biosynthetic process(GO:0045351) |
0.0 | 0.1 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.0 | 0.2 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.0 | 0.2 | GO:0043249 | erythrocyte maturation(GO:0043249) |
0.0 | 0.3 | GO:0071539 | protein localization to centrosome(GO:0071539) |
0.0 | 0.7 | GO:0002209 | behavioral fear response(GO:0001662) behavioral defense response(GO:0002209) |
0.0 | 0.3 | GO:1900452 | regulation of long term synaptic depression(GO:1900452) |
0.0 | 0.0 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
0.0 | 0.8 | GO:0035383 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 6.5 | GO:0031931 | TORC1 complex(GO:0031931) |
0.3 | 1.0 | GO:1990032 | parallel fiber(GO:1990032) |
0.2 | 5.9 | GO:0031430 | M band(GO:0031430) |
0.2 | 0.6 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
0.2 | 3.7 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.2 | 1.0 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.2 | 1.3 | GO:0071437 | invadopodium(GO:0071437) |
0.1 | 2.1 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.1 | 0.3 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
0.1 | 0.6 | GO:0036157 | outer dynein arm(GO:0036157) |
0.1 | 0.3 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.1 | 5.5 | GO:0016363 | nuclear matrix(GO:0016363) |
0.1 | 1.2 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.1 | 0.3 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.1 | 0.7 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
0.0 | 0.4 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.0 | 0.7 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.0 | 0.9 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 0.8 | GO:0000145 | exocyst(GO:0000145) |
0.0 | 0.8 | GO:0000795 | synaptonemal complex(GO:0000795) |
0.0 | 0.3 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 0.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 2.7 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.3 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.0 | 0.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 3.8 | GO:0030027 | lamellipodium(GO:0030027) |
0.0 | 1.0 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 0.0 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.0 | 0.7 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 0.6 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.1 | GO:0071014 | post-mRNA release spliceosomal complex(GO:0071014) |
0.0 | 2.0 | GO:0005759 | mitochondrial matrix(GO:0005759) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.7 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.4 | 1.2 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
0.3 | 1.6 | GO:0016453 | acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453) |
0.3 | 1.3 | GO:0071253 | connexin binding(GO:0071253) |
0.3 | 1.8 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.2 | 0.7 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437) |
0.2 | 0.6 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
0.2 | 0.9 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
0.2 | 1.0 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.2 | 3.0 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.2 | 3.0 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.1 | 1.0 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
0.1 | 2.0 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.1 | 0.7 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
0.1 | 0.4 | GO:0004980 | melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980) |
0.1 | 0.9 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
0.1 | 3.1 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.1 | 0.5 | GO:0004103 | choline kinase activity(GO:0004103) |
0.1 | 1.3 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 3.0 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.1 | 1.8 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.1 | 2.1 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.1 | 0.3 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379) |
0.1 | 0.5 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
0.1 | 0.2 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
0.1 | 0.3 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
0.1 | 1.0 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
0.1 | 0.3 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.1 | 2.3 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.1 | 1.2 | GO:0035380 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677) |
0.1 | 2.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.1 | 2.2 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693) |
0.0 | 1.1 | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
0.0 | 0.6 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.0 | 0.8 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
0.0 | 2.0 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.4 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.8 | GO:0034946 | 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466) |
0.0 | 0.8 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 1.1 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.0 | 0.3 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.0 | 0.8 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 1.2 | GO:0004521 | endoribonuclease activity(GO:0004521) |
0.0 | 0.6 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
0.0 | 0.4 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.4 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
0.0 | 2.6 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 0.3 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 0.4 | GO:0030331 | estrogen receptor binding(GO:0030331) |
0.0 | 1.0 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 2.6 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 1.1 | GO:0008175 | tRNA methyltransferase activity(GO:0008175) |