Motif ID: Pax4

Z-value: 0.482


Transcription factors associated with Pax4:

Gene SymbolEntrez IDGene Name
Pax4 ENSMUSG00000029706.9 Pax4



Activity profile for motif Pax4.

activity profile for motif Pax4


Sorted Z-values histogram for motif Pax4

Sorted Z-values for motif Pax4



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax4

PNG image of the network

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Top targets:


Showing 1 to 20 of 74 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_90738438 4.865 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr8_-_84773381 4.682 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chrX_+_9199865 4.196 ENSMUST00000069763.2
 Lancl3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr15_-_79164477 3.468 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr9_+_32696005 3.427 ENSMUST00000034534.6
ENSMUST00000050797.7
ENSMUST00000184887.1
 Ets1


E26 avian leukemia oncogene 1, 5' domain


chr8_-_70700070 3.270 ENSMUST00000116172.1
 Gm11175
predicted gene 11175
chr15_-_88978958 2.889 ENSMUST00000042594.6
ENSMUST00000109368.1
 Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr9_-_58159201 2.849 ENSMUST00000041477.7
 Islr
immunoglobulin superfamily containing leucine-rich repeat
chr13_-_101768154 2.812 ENSMUST00000055518.6
 Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chrX_+_142227923 2.445 ENSMUST00000042329.5
 Nxt2
nuclear transport factor 2-like export factor 2
chr2_-_168741898 2.420 ENSMUST00000109176.1
ENSMUST00000178504.1
 Atp9a

ATPase, class II, type 9A

chr2_+_73271925 2.336 ENSMUST00000090813.5
 Sp9
trans-acting transcription factor 9
chrX_+_142228177 2.190 ENSMUST00000112914.1
 Nxt2
nuclear transport factor 2-like export factor 2
chr13_+_23738804 1.993 ENSMUST00000040914.1
 Hist1h1c
histone cluster 1, H1c
chr4_-_88033328 1.927 ENSMUST00000078090.5
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_-_168741752 1.902 ENSMUST00000029060.4
 Atp9a
ATPase, class II, type 9A
chr5_-_103100054 1.849 ENSMUST00000112848.1
 Mapk10
mitogen-activated protein kinase 10
chr4_+_136357423 1.568 ENSMUST00000182167.1
 Gm17388
predicted gene, 17388
chr2_+_158667119 1.567 ENSMUST00000045503.4
 Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr2_+_158666690 1.496 ENSMUST00000103116.3
 Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 4.9 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.3 4.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 4.6 GO:0051028 mRNA transport(GO:0051028)
0.1 4.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.3 3.5 GO:0048484 enteric nervous system development(GO:0048484)
0.9 3.4 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.8 3.1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.6 2.9 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.3 2.8 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 2.1 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.3 2.0 GO:0016584 nucleosome positioning(GO:0016584)
0.2 1.9 GO:0007379 segment specification(GO:0007379)
0.3 1.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.5 1.5 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.5 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 1.4 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.3 1.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 1.2 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.0 1.0 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.9 GO:0030322 stabilization of membrane potential(GO:0030322)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 7.5 GO:0055037 recycling endosome(GO:0055037)
0.0 4.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.4 3.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 2.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 2.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.8 GO:0043204 perikaryon(GO:0043204)
0.0 1.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.6 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.6 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.2 3.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 3.1 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 2.9 GO:0008565 protein transporter activity(GO:0008565)
0.7 2.8 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 2.1 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 2.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 1.5 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.4 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.3 1.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.2 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.8 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)