Motif ID: Pax5

Z-value: 1.409


Transcription factors associated with Pax5:

Gene SymbolEntrez IDGene Name
Pax5 ENSMUSG00000014030.9 Pax5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax5mm10_v2_chr4_-_44704006_447040060.104.3e-01Click!


Activity profile for motif Pax5.

activity profile for motif Pax5


Sorted Z-values histogram for motif Pax5

Sorted Z-values for motif Pax5



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_152982240 12.465 ENSMUST00000044278.5
St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr11_-_102897123 12.397 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr16_+_45094036 12.374 ENSMUST00000061050.5
Ccdc80
coiled-coil domain containing 80
chr7_-_79386943 12.334 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr16_+_45093611 12.033 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr15_-_79164477 10.901 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr1_-_172297989 10.845 ENSMUST00000085913.4
ENSMUST00000097464.2
ENSMUST00000137679.1
Atp1a2


ATPase, Na+/K+ transporting, alpha 2 polypeptide


chr4_-_64046925 10.726 ENSMUST00000107377.3
Tnc
tenascin C
chr9_+_37367354 10.085 ENSMUST00000051839.7
Hepacam
hepatocyte cell adhesion molecule
chr11_-_102897146 9.111 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr19_-_57008187 8.740 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
Afap1l2



actin filament associated protein 1-like 2



chr14_+_54936456 8.603 ENSMUST00000037814.6
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr5_+_89027959 8.448 ENSMUST00000130041.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr3_+_90537306 7.729 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr3_+_90537242 7.647 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr10_+_127725392 7.340 ENSMUST00000026466.3
Tac2
tachykinin 2
chr3_+_89520152 7.208 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr7_-_79149042 7.199 ENSMUST00000032825.8
ENSMUST00000107409.3
Mfge8

milk fat globule-EGF factor 8 protein

chr2_-_162661075 7.012 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
Ptprt



protein tyrosine phosphatase, receptor type, T



chr12_+_16653470 6.616 ENSMUST00000111064.1
Ntsr2
neurotensin receptor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 347 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.6 21.6 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.9 19.0 GO:0015701 bicarbonate transport(GO:0015701)
0.2 16.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
1.4 16.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
1.1 13.8 GO:0070842 aggresome assembly(GO:0070842)
1.2 12.1 GO:0090527 actin filament reorganization(GO:0090527)
0.8 11.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.9 10.9 GO:0048484 enteric nervous system development(GO:0048484)
3.6 10.8 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
3.6 10.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 8.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.5 8.4 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.4 8.4 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.1 8.2 GO:0051592 response to calcium ion(GO:0051592)
0.1 8.1 GO:0006813 potassium ion transport(GO:0006813)
0.1 7.7 GO:0007601 visual perception(GO:0007601)
1.2 7.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.4 7.3 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.3 7.1 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 7.0 GO:0008360 regulation of cell shape(GO:0008360)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 146 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 68.0 GO:0045211 postsynaptic membrane(GO:0045211)
2.2 35.1 GO:0005614 interstitial matrix(GO:0005614)
5.4 21.5 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 18.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 15.8 GO:0005887 integral component of plasma membrane(GO:0005887)
0.2 13.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 13.3 GO:0005901 caveola(GO:0005901)
0.1 12.2 GO:0030027 lamellipodium(GO:0030027)
0.2 11.7 GO:0005581 collagen trimer(GO:0005581)
0.0 10.9 GO:0030424 axon(GO:0030424)
0.0 10.9 GO:0005768 endosome(GO:0005768)
1.5 10.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.2 9.9 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 7.4 GO:0043204 perikaryon(GO:0043204)
0.1 6.8 GO:0031201 SNARE complex(GO:0031201)
0.1 6.1 GO:0005871 kinesin complex(GO:0005871)
0.5 5.6 GO:0043083 synaptic cleft(GO:0043083)
0.4 4.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 4.7 GO:0043218 compact myelin(GO:0043218)
1.5 4.4 GO:0071953 elastic fiber(GO:0071953)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 218 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 34.0 GO:0005178 integrin binding(GO:0005178)
0.9 24.4 GO:0001968 fibronectin binding(GO:0001968)
5.0 15.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 14.1 GO:0046875 ephrin receptor binding(GO:0046875)
1.3 12.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
2.1 12.3 GO:0019841 retinol binding(GO:0019841)
1.0 12.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
1.7 11.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.5 11.7 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
1.8 10.7 GO:0045545 syndecan binding(GO:0045545)
1.4 9.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
2.1 8.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 7.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 7.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
1.4 7.1 GO:0042895 antibiotic transporter activity(GO:0042895)
0.6 7.0 GO:0070097 delta-catenin binding(GO:0070097)
0.8 6.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 6.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 6.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.5 5.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)