Motif ID: Pax7

Z-value: 0.416


Transcription factors associated with Pax7:

Gene SymbolEntrez IDGene Name
Pax7 ENSMUSG00000028736.7 Pax7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax7mm10_v2_chr4_-_139833524_139833535-0.264.4e-02Click!


Activity profile for motif Pax7.

activity profile for motif Pax7


Sorted Z-values histogram for motif Pax7

Sorted Z-values for motif Pax7



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_67113909 2.937 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr5_-_62766153 2.515 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_+_96268654 2.509 ENSMUST00000098843.2
Hist2h3b
histone cluster 2, H3b
chr3_+_55461758 2.392 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr13_-_22042949 2.289 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr13_+_23533869 2.282 ENSMUST00000073261.2
Hist1h2af
histone cluster 1, H2af
chr4_+_102589687 2.257 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr9_-_96719404 2.255 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr4_-_14621805 2.169 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr1_-_55226768 1.946 ENSMUST00000027121.8
ENSMUST00000114428.2
Rftn2

raftlin family member 2

chr9_-_96719549 1.913 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr11_-_115276973 1.820 ENSMUST00000021078.2
Fdxr
ferredoxin reductase
chr13_-_23934156 1.789 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr15_+_9436028 1.734 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr6_+_145934113 1.671 ENSMUST00000032383.7
Sspn
sarcospan
chr15_-_37459327 1.596 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr1_+_72284367 1.356 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr5_+_26817357 1.353 ENSMUST00000071500.6
Dpp6
dipeptidylpeptidase 6
chr4_+_136286061 1.338 ENSMUST00000069195.4
ENSMUST00000130658.1
Zfp46

zinc finger protein 46

chr6_-_57535422 1.266 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr10_-_62379852 1.251 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
Hk1



hexokinase 1



chr11_-_87359011 1.216 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr2_+_65620829 1.049 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr4_-_14621494 1.038 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr5_-_92348871 1.017 ENSMUST00000038816.6
ENSMUST00000118006.1
Cxcl10

chemokine (C-X-C motif) ligand 10

chr11_-_102946688 1.006 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr14_+_55560010 0.930 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr4_+_108719649 0.835 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr11_+_116843278 0.718 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr8_-_34965631 0.696 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr15_-_64922290 0.641 ENSMUST00000023007.5
Adcy8
adenylate cyclase 8
chr14_+_55559993 0.544 ENSMUST00000117236.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr2_-_37359274 0.521 ENSMUST00000009174.8
Pdcl
phosducin-like
chr13_+_76579670 0.510 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr8_+_107031218 0.504 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr10_+_85386813 0.469 ENSMUST00000105307.1
ENSMUST00000020231.3
Btbd11

BTB (POZ) domain containing 11

chr19_+_41933464 0.434 ENSMUST00000026154.7
Zdhhc16
zinc finger, DHHC domain containing 16
chr7_-_45510400 0.410 ENSMUST00000033096.7
Nucb1
nucleobindin 1
chr11_-_29247208 0.401 ENSMUST00000020754.3
Ccdc104
coiled-coil domain containing 104
chr3_+_32436376 0.341 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr2_+_125136692 0.314 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr7_-_98656530 0.296 ENSMUST00000038359.4
2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr14_-_76110760 0.287 ENSMUST00000022585.3
Gpalpp1
GPALPP motifs containing 1
chr2_-_150255591 0.245 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr19_+_8802486 0.219 ENSMUST00000172175.1
Zbtb3
zinc finger and BTB domain containing 3
chr18_+_38993126 0.204 ENSMUST00000097593.2
Arhgap26
Rho GTPase activating protein 26
chr9_+_21955747 0.198 ENSMUST00000053583.5
Swsap1
SWIM type zinc finger 7 associated protein 1
chr7_-_46667375 0.186 ENSMUST00000107669.2
Tph1
tryptophan hydroxylase 1
chr13_+_67833235 0.175 ENSMUST00000060609.7
Gm10037
predicted gene 10037
chr2_+_125068118 0.143 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr9_-_71163224 0.137 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr4_-_14621669 0.135 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr7_-_137410717 0.127 ENSMUST00000120340.1
ENSMUST00000117404.1
ENSMUST00000068996.6
9430038I01Rik


RIKEN cDNA 9430038I01 gene


chr2_+_32727682 0.108 ENSMUST00000113242.2
Sh2d3c
SH2 domain containing 3C
chr13_+_22043189 0.073 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr3_-_106790143 0.063 ENSMUST00000038845.8
Cd53
CD53 antigen
chr2_-_116067391 0.035 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chrX_+_16619698 0.012 ENSMUST00000026013.5
Maoa
monoamine oxidase A
chr12_+_72441852 0.010 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0019532 oxalate transport(GO:0019532)
0.4 1.8 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.3 1.0 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.3 1.0 GO:0061743 motor learning(GO:0061743)
0.3 1.9 GO:0032596 protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227)
0.3 1.0 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 0.7 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.2 1.3 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 0.5 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.2 2.3 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 0.5 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 1.8 GO:0070995 NADPH oxidation(GO:0070995)
0.1 2.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 1.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 2.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 2.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 3.4 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.4 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.2 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 4.2 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.1 GO:0015791 polyol transport(GO:0015791) urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.0 0.6 GO:0007616 long-term memory(GO:0007616)
0.0 1.6 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0044301 climbing fiber(GO:0044301)
0.1 4.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 2.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.4 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.5 GO:0090543 Flemming body(GO:0090543)
0.1 1.3 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 2.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.3 GO:0000786 nucleosome(GO:0000786)
0.0 4.2 GO:0072562 blood microparticle(GO:0072562)
0.0 1.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 3.5 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 1.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 3.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 1.3 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 3.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 1.8 GO:0070402 NADPH binding(GO:0070402)
0.1 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 2.3 GO:0030552 cAMP binding(GO:0030552)
0.1 2.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 2.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 1.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 2.3 GO:0042393 histone binding(GO:0042393)