Motif ID: Pgr_Nr3c1

Z-value: 0.529

Transcription factors associated with Pgr_Nr3c1:

Gene SymbolEntrez IDGene Name
Nr3c1 ENSMUSG00000024431.8 Nr3c1
Pgr ENSMUSG00000031870.10 Pgr

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c1mm10_v2_chr18_-_39487096_39487245-0.181.7e-01Click!


Activity profile for motif Pgr_Nr3c1.

activity profile for motif Pgr_Nr3c1


Sorted Z-values histogram for motif Pgr_Nr3c1

Sorted Z-values for motif Pgr_Nr3c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pgr_Nr3c1

PNG image of the network

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Top targets:


Showing 1 to 20 of 137 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_97565436 7.602 ENSMUST00000038160.4
 Lum
lumican
chr18_+_20665250 4.963 ENSMUST00000075312.3
 Ttr
transthyretin
chr4_-_44710408 2.648 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
 Pax5









paired box gene 5









chr9_+_91368970 2.557 ENSMUST00000172646.1
 Zic4
zinc finger protein of the cerebellum 4
chr9_+_91368811 2.426 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr14_-_16575456 1.883 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta
chr19_+_55894508 1.487 ENSMUST00000142291.1
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr7_-_142576492 1.348 ENSMUST00000140716.1
 H19
H19 fetal liver mRNA
chr1_-_171240055 1.346 ENSMUST00000131286.1
 Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr3_-_33082004 1.302 ENSMUST00000108225.3
 Pex5l
peroxisomal biogenesis factor 5-like
chr7_+_144838590 1.198 ENSMUST00000105898.1
 Fgf3
fibroblast growth factor 3
chr3_-_146839365 1.098 ENSMUST00000084614.3
 Gm10288
predicted gene 10288
chr5_+_24364804 0.994 ENSMUST00000030834.4
ENSMUST00000115090.1
 Nos3

nitric oxide synthase 3, endothelial cell

chr18_-_15063560 0.932 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chr4_-_136898803 0.927 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr2_-_122611238 0.901 ENSMUST00000028624.8
 Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr12_-_73047179 0.873 ENSMUST00000050029.7
 Six1
sine oculis-related homeobox 1
chr17_-_68004075 0.860 ENSMUST00000024840.5
 Arhgap28
Rho GTPase activating protein 28
chr13_+_91461050 0.854 ENSMUST00000004094.8
ENSMUST00000042122.8
 Ssbp2

single-stranded DNA binding protein 2

chr11_-_110168073 0.848 ENSMUST00000044850.3
 Abca9
ATP-binding cassette, sub-family A (ABC1), member 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 7.6 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
1.0 5.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 2.6 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.3 1.9 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 1.6 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.5 1.5 GO:0015889 cobalamin transport(GO:0015889)
0.2 1.5 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 1.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 1.3 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.1 1.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.3 1.0 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.3 0.9 GO:0006601 creatine biosynthetic process(GO:0006601)
0.3 0.9 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.2 0.9 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.2 0.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.8 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.7 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.2 0.6 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 7.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4 1.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.2 1.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.5 1.4 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.0 1.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.1 0.9 GO:0045298 tubulin complex(GO:0045298)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.7 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.1 7.6 GO:0005518 collagen binding(GO:0005518)
0.6 5.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 1.9 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.3 1.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 1.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.3 GO:0048038 quinone binding(GO:0048038)
0.1 1.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 1.0 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.0 0.9 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 0.8 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
0.2 0.7 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.7 GO:0048185 activin binding(GO:0048185)
0.1 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.6 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.1 0.5 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)