Motif ID: Pou2f1

Z-value: 1.287


Transcription factors associated with Pou2f1:

Gene SymbolEntrez IDGene Name
Pou2f1 ENSMUSG00000026565.12 Pou2f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou2f1mm10_v2_chr1_-_166002591_166002609-0.255.7e-02Click!


Activity profile for motif Pou2f1.

activity profile for motif Pou2f1


Sorted Z-values histogram for motif Pou2f1

Sorted Z-values for motif Pou2f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_137553517 16.191 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
 Actl6b




actin-like 6B




chr13_+_83573577 13.066 ENSMUST00000185052.1
 Mef2c
myocyte enhancer factor 2C
chr12_-_108003414 12.297 ENSMUST00000109887.1
ENSMUST00000109891.2
 Bcl11b

B cell leukemia/lymphoma 11B

chr11_+_58948890 11.153 ENSMUST00000078267.3
 Hist3h2ba
histone cluster 3, H2ba
chr13_-_21787218 10.346 ENSMUST00000091751.2
 Hist1h2an
histone cluster 1, H2an
chr5_-_109558957 10.216 ENSMUST00000044579.7
 Crlf2
cytokine receptor-like factor 2
chr12_-_108003594 10.160 ENSMUST00000066060.4
 Bcl11b
B cell leukemia/lymphoma 11B
chr10_+_29211637 9.763 ENSMUST00000092627.4
 9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr2_-_25580099 9.738 ENSMUST00000114217.1
 Gm996
predicted gene 996
chr13_-_22042949 9.672 ENSMUST00000091741.4
 Hist1h2ag
histone cluster 1, H2ag
chr13_+_21810428 9.479 ENSMUST00000091745.5
 Hist1h2ao
histone cluster 1, H2ao
chr4_+_13751297 9.454 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr13_+_23574381 9.239 ENSMUST00000090776.4
 Hist1h2ad
histone cluster 1, H2ad
chr13_+_23751069 8.594 ENSMUST00000078369.1
 Hist1h2ab
histone cluster 1, H2ab
chr7_+_45783686 8.277 ENSMUST00000118564.1
ENSMUST00000133428.1
 Lmtk3

lemur tyrosine kinase 3

chrX_-_51681856 7.932 ENSMUST00000114871.1
 Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr10_-_81230773 7.816 ENSMUST00000047408.4
 Atcay
ataxia, cerebellar, Cayman type homolog (human)
chr1_+_58210397 7.548 ENSMUST00000040442.5
 Aox4
aldehyde oxidase 4
chr4_+_85205120 7.143 ENSMUST00000107188.3
 Sh3gl2
SH3-domain GRB2-like 2
chr13_-_23571151 6.981 ENSMUST00000102969.3
 Hist1h2ae
histone cluster 1, H2ae

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 50.3 GO:0006342 chromatin silencing(GO:0006342)
0.3 35.0 GO:0006333 chromatin assembly or disassembly(GO:0006333)
3.7 22.5 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
4.4 13.1 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.2 12.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.5 10.9 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
1.7 10.2 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.2 9.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.7 8.3 GO:0002227 innate immune response in mucosa(GO:0002227)
1.3 7.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
2.6 7.8 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
2.5 7.5 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 7.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.8 6.6 GO:0005513 detection of calcium ion(GO:0005513)
1.6 6.3 GO:0042938 dipeptide transport(GO:0042938)
0.3 5.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 5.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 5.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.4 5.4 GO:0051601 exocyst localization(GO:0051601)
0.1 5.4 GO:0035914 skeletal muscle cell differentiation(GO:0035914)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 34.7 GO:0043005 neuron projection(GO:0043005)
0.1 30.9 GO:0000790 nuclear chromatin(GO:0000790)
0.7 22.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.8 16.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 13.7 GO:0016607 nuclear speck(GO:0016607)
0.1 10.9 GO:0016605 PML body(GO:0016605)
0.2 9.5 GO:0016363 nuclear matrix(GO:0016363)
0.4 6.6 GO:0031045 dense core granule(GO:0031045)
0.9 5.4 GO:0000235 astral microtubule(GO:0000235)
0.3 5.4 GO:0000145 exocyst(GO:0000145)
0.0 5.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.3 5.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.4 4.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 3.4 GO:0097228 sperm principal piece(GO:0097228)
0.2 3.4 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 3.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 3.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 3.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.9 GO:0016604 nuclear body(GO:0016604)
0.5 2.7 GO:0032807 DNA ligase IV complex(GO:0032807)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 63.4 GO:0003677 DNA binding(GO:0003677)
0.0 13.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
1.2 13.1 GO:0003680 AT DNA binding(GO:0003680)
0.1 10.9 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 9.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 7.9 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.1 7.9 GO:0005125 cytokine activity(GO:0005125)
0.2 7.8 GO:0050699 WW domain binding(GO:0050699)
1.9 7.5 GO:0030151 molybdenum ion binding(GO:0030151)
0.3 6.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
1.3 6.3 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 6.1 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 5.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 5.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 5.2 GO:0000149 SNARE binding(GO:0000149)
1.7 5.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 4.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 4.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 4.0 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 3.8 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)