Motif ID: Pou2f2_Pou3f1

Z-value: 1.556

Transcription factors associated with Pou2f2_Pou3f1:

Gene SymbolEntrez IDGene Name
Pou2f2 ENSMUSG00000008496.12 Pou2f2
Pou3f1 ENSMUSG00000090125.2 Pou3f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f1mm10_v2_chr4_+_124657646_1246576560.283.3e-02Click!
Pou2f2mm10_v2_chr7_-_25132473_251325120.133.4e-01Click!


Activity profile for motif Pou2f2_Pou3f1.

activity profile for motif Pou2f2_Pou3f1


Sorted Z-values histogram for motif Pou2f2_Pou3f1

Sorted Z-values for motif Pou2f2_Pou3f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f2_Pou3f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_24507099 39.001 ENSMUST00000177228.1
 Zfp428
zinc finger protein 428
chr13_-_22042949 19.905 ENSMUST00000091741.4
 Hist1h2ag
histone cluster 1, H2ag
chr13_+_23751069 18.597 ENSMUST00000078369.1
 Hist1h2ab
histone cluster 1, H2ab
chr13_-_21833575 18.190 ENSMUST00000081342.5
 Hist1h2ap
histone cluster 1, H2ap
chr7_+_24507006 17.487 ENSMUST00000176880.1
 Zfp428
zinc finger protein 428
chr13_-_23571151 16.860 ENSMUST00000102969.3
 Hist1h2ae
histone cluster 1, H2ae
chr13_-_22035589 16.487 ENSMUST00000091742.4
 Hist1h2ah
histone cluster 1, H2ah
chr3_-_96240317 15.924 ENSMUST00000078756.5
 Hist2h2aa2
histone cluster 2, H2aa2
chr13_+_23574381 15.839 ENSMUST00000090776.4
 Hist1h2ad
histone cluster 1, H2ad
chr3_+_96245530 13.132 ENSMUST00000074976.6
 Hist2h2aa1
histone cluster 2, H2aa1
chr7_+_24507122 13.120 ENSMUST00000177205.1
 Zfp428
zinc finger protein 428
chr7_+_24507057 12.766 ENSMUST00000071361.6
 Zfp428
zinc finger protein 428
chr13_-_23683941 12.125 ENSMUST00000171127.1
 Hist1h2ac
histone cluster 1, H2ac
chr11_+_58954675 12.073 ENSMUST00000047697.5
ENSMUST00000108817.3
 Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr11_+_58948890 11.328 ENSMUST00000078267.3
 Hist3h2ba
histone cluster 3, H2ba
chr7_+_126776939 10.384 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
 Ypel3






yippee-like 3 (Drosophila)






chr3_-_96220880 10.201 ENSMUST00000090782.3
 Hist2h2ac
histone cluster 2, H2ac
chr13_+_23533869 10.019 ENSMUST00000073261.2
 Hist1h2af
histone cluster 1, H2af
chr2_-_30474199 9.474 ENSMUST00000065134.2
 Ier5l
immediate early response 5-like
chr13_-_21787218 9.381 ENSMUST00000091751.2
 Hist1h2an
histone cluster 1, H2an

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 185.2 GO:0006342 chromatin silencing(GO:0006342)
0.3 26.1 GO:0006334 nucleosome assembly(GO:0006334)
1.7 20.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 11.6 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.3 11.5 GO:0060074 synapse maturation(GO:0060074)
2.1 10.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
2.8 8.4 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
1.5 7.7 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 6.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.9 6.1 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.2 6.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.5 5.5 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.3 5.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.7 4.7 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.2 4.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 4.2 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.7 4.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
1.2 3.5 GO:0070269 pyroptosis(GO:0070269)
0.5 3.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 3.5 GO:0014049 positive regulation of glutamate secretion(GO:0014049)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 127.7 GO:0000790 nuclear chromatin(GO:0000790)
1.8 61.9 GO:0000788 nuclear nucleosome(GO:0000788)
1.1 45.9 GO:0000786 nucleosome(GO:0000786)
0.9 8.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 7.9 GO:0005776 autophagosome(GO:0005776)
0.3 6.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 5.6 GO:0042734 presynaptic membrane(GO:0042734)
1.4 5.5 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 5.1 GO:0044295 axonal growth cone(GO:0044295)
0.6 4.3 GO:0035102 PRC1 complex(GO:0035102)
0.2 4.2 GO:0032279 asymmetric synapse(GO:0032279)
0.1 4.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.9 3.5 GO:0061702 inflammasome complex(GO:0061702)
0.0 3.0 GO:0005681 spliceosomal complex(GO:0005681)
0.2 2.9 GO:0042788 polysomal ribosome(GO:0042788)
0.0 2.7 GO:0043204 perikaryon(GO:0043204)
0.0 2.6 GO:0030496 midbody(GO:0030496)
0.3 1.4 GO:0001651 dense fibrillar component(GO:0001651)
0.0 1.4 GO:0016234 inclusion body(GO:0016234)
0.1 1.3 GO:0044300 cerebellar mossy fiber(GO:0044300)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 105.2 GO:0003677 DNA binding(GO:0003677)
0.0 80.7 GO:0046872 metal ion binding(GO:0046872)
0.1 67.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 10.2 GO:0005496 steroid binding(GO:0005496)
0.1 8.8 GO:0043130 ubiquitin binding(GO:0043130)
2.8 8.4 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.2 7.5 GO:0070888 E-box binding(GO:0070888)
0.4 6.1 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.1 6.1 GO:0005262 calcium channel activity(GO:0005262)
0.2 4.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.8 4.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.7 4.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.0 4.0 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 3.6 GO:0042393 histone binding(GO:0042393)
0.1 3.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 3.5 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.1 3.3 GO:0003785 actin monomer binding(GO:0003785)
0.2 2.9 GO:0097109 neuroligin family protein binding(GO:0097109)
0.3 2.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 2.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)