Motif ID: Pou3f3

Z-value: 0.397


Transcription factors associated with Pou3f3:

Gene SymbolEntrez IDGene Name
Pou3f3 ENSMUSG00000045515.2 Pou3f3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f3mm10_v2_chr1_+_42697146_42697146-0.811.4e-14Click!


Activity profile for motif Pou3f3.

activity profile for motif Pou3f3


Sorted Z-values histogram for motif Pou3f3

Sorted Z-values for motif Pou3f3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou3f3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_26229707 4.120 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr4_+_134510999 2.661 ENSMUST00000105866.2
Aunip
aurora kinase A and ninein interacting protein
chr11_+_88294043 2.431 ENSMUST00000037268.4
1700106J16Rik
RIKEN cDNA 1700106J16 gene
chr3_+_83766300 2.172 ENSMUST00000029625.7
Sfrp2
secreted frizzled-related protein 2
chr4_-_149137536 2.106 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
Apitd1



apoptosis-inducing, TAF9-like domain 1



chr13_+_63015167 2.026 ENSMUST00000021911.8
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr13_+_63014934 1.934 ENSMUST00000091560.4
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr13_+_72628831 1.676 ENSMUST00000169028.1
Irx2
Iroquois related homeobox 2 (Drosophila)
chr5_-_74065736 1.674 ENSMUST00000145016.1
Usp46
ubiquitin specific peptidase 46
chrX_+_150594420 1.640 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr13_-_83729544 1.527 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr2_+_25180737 1.206 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr7_-_126792469 1.154 ENSMUST00000032936.6
Ppp4c
protein phosphatase 4, catalytic subunit
chr4_+_101986626 1.029 ENSMUST00000106914.1
Gm12789
predicted gene 12789
chr16_-_89508313 0.597 ENSMUST00000056118.2
Krtap7-1
keratin associated protein 7-1
chr15_-_42676967 0.486 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chr17_-_50094277 0.403 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr5_-_66514815 0.336 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr2_+_164823001 0.252 ENSMUST00000132282.1
Zswim1
zinc finger SWIM-type containing 1
chr5_+_66676098 0.243 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr2_-_154372702 0.189 ENSMUST00000028990.3
ENSMUST00000109730.2
Cdk5rap1

CDK5 regulatory subunit associated protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:1904956 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 2.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 1.7 GO:0008343 adult feeding behavior(GO:0008343)
0.2 1.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 0.5 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.1 4.0 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.2 GO:0007412 axon target recognition(GO:0007412)
0.0 0.2 GO:1900864 positive regulation of translational fidelity(GO:0045903) mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 1.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 2.7 GO:0007051 spindle organization(GO:0007051)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.5 1.6 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 1.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 2.7 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 4.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 1.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)