Motif ID: Pou3f4

Z-value: 0.785


Transcription factors associated with Pou3f4:

Gene SymbolEntrez IDGene Name
Pou3f4 ENSMUSG00000056854.3 Pou3f4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f4mm10_v2_chrX_+_110814390_1108144130.311.8e-02Click!


Activity profile for motif Pou3f4.

activity profile for motif Pou3f4


Sorted Z-values histogram for motif Pou3f4

Sorted Z-values for motif Pou3f4



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou3f4

PNG image of the network

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Top targets:


Showing 1 to 20 of 130 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_113765998 7.663 ENSMUST00000046687.9
 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr5_+_147188678 6.158 ENSMUST00000065382.5
 Gsx1
GS homeobox 1
chr15_+_92161343 6.124 ENSMUST00000068378.5
 Cntn1
contactin 1
chr19_+_55741810 5.609 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr19_+_55742242 4.851 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
 Tcf7l2






transcription factor 7 like 2, T cell specific, HMG box






chr18_+_56432116 4.129 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr19_+_55741884 4.029 ENSMUST00000111658.3
ENSMUST00000111654.1
 Tcf7l2

transcription factor 7 like 2, T cell specific, HMG box

chr10_+_90576252 3.902 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
 Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr19_+_55742056 3.852 ENSMUST00000111659.2
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr17_-_58991343 3.645 ENSMUST00000025064.7
 2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr6_+_34384218 3.329 ENSMUST00000038383.7
ENSMUST00000115051.1
 Akr1b10

aldo-keto reductase family 1, member B10 (aldose reductase)

chr10_-_64090241 3.234 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr7_+_87803815 2.868 ENSMUST00000125009.1
ENSMUST00000155358.1
 Grm5

glutamate receptor, metabotropic 5

chr1_+_159737510 2.866 ENSMUST00000111669.3
 Tnr
tenascin R
chr6_+_21215472 2.739 ENSMUST00000081542.5
 Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr14_-_78088994 2.708 ENSMUST00000118785.2
ENSMUST00000066437.4
 Fam216b

family with sequence similarity 216, member B

chr10_-_64090265 2.446 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr4_+_41569775 2.352 ENSMUST00000102963.3
 Dnaic1
dynein, axonemal, intermediate chain 1
chr16_-_22439570 2.258 ENSMUST00000170393.1
 Etv5
ets variant gene 5
chr11_+_71749914 2.178 ENSMUST00000150531.1
 Wscd1
WSC domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.3 18.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.7 6.2 GO:0021984 adenohypophysis development(GO:0021984)
0.1 6.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.4 5.7 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
1.6 4.8 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.6 4.7 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.8 4.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 3.9 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.4 3.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 3.0 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
1.0 2.9 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.3 2.9 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 2.7 GO:0045475 locomotor rhythm(GO:0045475)
0.6 2.4 GO:1904192 prostate gland stromal morphogenesis(GO:0060741) cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.3 2.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.4 2.2 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.4 2.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 2.2 GO:0009636 response to toxic substance(GO:0009636)
0.4 1.8 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 1.7 GO:1990403 embryonic brain development(GO:1990403)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 18.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 12.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 8.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 7.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 4.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.3 3.9 GO:0097449 astrocyte projection(GO:0097449)
0.0 3.0 GO:0008021 synaptic vesicle(GO:0008021)
1.0 2.9 GO:0072534 perineuronal net(GO:0072534)
0.1 2.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.6 2.4 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.4 2.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 2.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 1.5 GO:0071439 clathrin complex(GO:0071439)
0.3 1.3 GO:0097227 sperm annulus(GO:0097227)
0.0 1.3 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.1 GO:0043195 terminal bouton(GO:0043195)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 18.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 6.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 6.1 GO:0030246 carbohydrate binding(GO:0030246)
0.5 4.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.4 4.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 4.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 3.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 3.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 3.3 GO:0052650 retinal binding(GO:0016918) NADP-retinol dehydrogenase activity(GO:0052650)
0.7 3.0 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
1.0 2.9 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.2 2.9 GO:0046625 sphingolipid binding(GO:0046625)
0.5 2.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 2.5 GO:0003774 motor activity(GO:0003774)
0.1 2.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.4 2.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 2.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.9 GO:0005178 integrin binding(GO:0005178)
0.0 1.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.5 1.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)