Motif ID: Pou4f3

Z-value: 0.436


Transcription factors associated with Pou4f3:

Gene SymbolEntrez IDGene Name
Pou4f3 ENSMUSG00000024497.3 Pou4f3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou4f3mm10_v2_chr18_+_42394539_42394575-0.255.7e-02Click!


Activity profile for motif Pou4f3.

activity profile for motif Pou4f3


Sorted Z-values histogram for motif Pou4f3

Sorted Z-values for motif Pou4f3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou4f3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_140671400 2.267 ENSMUST00000056760.3
 Flrt3
fibronectin leucine rich transmembrane protein 3
chr10_+_37139558 1.916 ENSMUST00000062667.3
 5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr1_+_194619815 1.873 ENSMUST00000027952.5
 Plxna2
plexin A2
chr4_-_58499398 1.774 ENSMUST00000107570.1
 Lpar1
lysophosphatidic acid receptor 1
chr1_-_126830632 1.768 ENSMUST00000112583.1
ENSMUST00000094609.3
 Nckap5

NCK-associated protein 5

chr17_-_48432723 1.335 ENSMUST00000046549.3
 Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr9_+_123366921 1.061 ENSMUST00000038863.7
 Lars2
leucyl-tRNA synthetase, mitochondrial
chr1_-_126830786 1.049 ENSMUST00000162646.1
 Nckap5
NCK-associated protein 5
chr13_-_58354862 0.903 ENSMUST00000043605.5
 Kif27
kinesin family member 27
chr10_+_102158858 0.862 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
 Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chrX_+_9885622 0.861 ENSMUST00000067529.2
ENSMUST00000086165.3
 Sytl5

synaptotagmin-like 5

chr10_-_76110956 0.813 ENSMUST00000120757.1
 Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr10_-_29144194 0.739 ENSMUST00000070359.2
 Gm9996
predicted gene 9996
chr7_-_138909492 0.668 ENSMUST00000106112.1
 Bnip3
BCL2/adenovirus E1B interacting protein 3
chr5_+_92809372 0.564 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chr13_+_60601921 0.556 ENSMUST00000077453.5
 Dapk1
death associated protein kinase 1
chr1_+_45795485 0.501 ENSMUST00000147308.1
 Wdr75
WD repeat domain 75
chr15_+_79690869 0.498 ENSMUST00000046463.8
 Gtpbp1
GTP binding protein 1
chr11_+_114675431 0.484 ENSMUST00000045779.5
 Ttyh2
tweety homolog 2 (Drosophila)
chr1_+_109983737 0.446 ENSMUST00000172005.1
 Cdh7
cadherin 7, type 2
chr8_+_83666827 0.434 ENSMUST00000019608.5
 Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr17_+_21691860 0.423 ENSMUST00000072133.4
 Gm10226
predicted gene 10226
chr14_+_69347587 0.411 ENSMUST00000064831.5
 Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr7_+_35802593 0.393 ENSMUST00000052454.2
 E130304I02Rik
RIKEN cDNA E130304I02 gene
chr5_-_120612558 0.321 ENSMUST00000140554.1
ENSMUST00000031599.2
ENSMUST00000177800.1
 1110008J03Rik


RIKEN cDNA 1110008J03 gene


chr5_-_118244861 0.316 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
 Rnft2



ring finger protein, transmembrane 2



chr4_+_63558748 0.310 ENSMUST00000077709.4
 6330416G13Rik
RIKEN cDNA 6330416G13 gene
chr9_+_110132015 0.303 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
 Smarcc1




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1




chr16_+_11406618 0.300 ENSMUST00000122168.1
 Snx29
sorting nexin 29
chr7_-_38019505 0.294 ENSMUST00000085513.4
 Uri1
URI1, prefoldin-like chaperone
chr2_-_160619971 0.265 ENSMUST00000109473.1
 Gm14221
predicted gene 14221
chr8_-_83458386 0.265 ENSMUST00000081506.3
 Scoc
short coiled-coil protein
chr2_+_36230426 0.256 ENSMUST00000062069.5
 Ptgs1
prostaglandin-endoperoxide synthase 1
chr3_+_32436151 0.249 ENSMUST00000029201.7
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr17_-_33033367 0.247 ENSMUST00000087654.4
 Zfp763
zinc finger protein 763
chr18_+_56562443 0.240 ENSMUST00000130163.1
ENSMUST00000132628.1
 Phax

phosphorylated adaptor for RNA export

chr12_+_72536342 0.214 ENSMUST00000044352.6
 Pcnxl4
pecanex-like 4 (Drosophila)
chr4_-_119190005 0.197 ENSMUST00000138395.1
ENSMUST00000156746.1
 Ermap

erythroblast membrane-associated protein

chr3_-_33082004 0.190 ENSMUST00000108225.3
 Pex5l
peroxisomal biogenesis factor 5-like
chr5_-_117287583 0.189 ENSMUST00000111973.1
ENSMUST00000036951.6
 Pebp1

phosphatidylethanolamine binding protein 1

chr5_-_3647806 0.187 ENSMUST00000119783.1
ENSMUST00000007559.8
 Gatad1

GATA zinc finger domain containing 1

chr4_+_101986626 0.182 ENSMUST00000106914.1
 Gm12789
predicted gene 12789
chr10_+_29143996 0.170 ENSMUST00000092629.2
 Soga3
SOGA family member 3
chr11_+_117809687 0.158 ENSMUST00000120928.1
ENSMUST00000175737.1
 Syngr2

synaptogyrin 2

chr11_+_117809653 0.145 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
 Syngr2

Gm20708
synaptogyrin 2

predicted gene 20708
chr5_+_13398688 0.140 ENSMUST00000125629.1
 Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr7_-_101837776 0.104 ENSMUST00000165052.1
 Inppl1
inositol polyphosphate phosphatase-like 1
chr10_-_63927434 0.097 ENSMUST00000079279.3
 Gm10118
predicted gene 10118
chr14_-_75754475 0.090 ENSMUST00000049168.7
 Cog3
component of oligomeric golgi complex 3
chr2_+_4300462 0.084 ENSMUST00000175669.1
 Frmd4a
FERM domain containing 4A
chr17_+_34647128 0.050 ENSMUST00000015605.8
ENSMUST00000182587.1
 Atf6b

activating transcription factor 6 beta

chr10_+_97482350 0.044 ENSMUST00000163448.2
 Dcn
decorin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.4 1.8 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 0.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) response to cobalt ion(GO:0032025)
0.2 2.0 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.4 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.1 0.8 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 0.3 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.1 1.3 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.9 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.6 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 1.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 0.5 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.5 GO:1903146 regulation of mitophagy(GO:1903146)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 2.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.4 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 2.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 1.3 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.8 GO:0005402 cation:sugar symporter activity(GO:0005402)
0.0 1.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)