Motif ID: Pou5f1

Z-value: 2.217


Transcription factors associated with Pou5f1:

Gene SymbolEntrez IDGene Name
Pou5f1 ENSMUSG00000024406.10 Pou5f1



Activity profile for motif Pou5f1.

activity profile for motif Pou5f1


Sorted Z-values histogram for motif Pou5f1

Sorted Z-values for motif Pou5f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou5f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 69.152 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr8_+_54954728 40.700 ENSMUST00000033915.7
 Gpm6a
glycoprotein m6a
chr6_-_55681257 40.603 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr7_+_24507099 36.981 ENSMUST00000177228.1
 Zfp428
zinc finger protein 428
chr4_+_97772734 34.222 ENSMUST00000152023.1
 Nfia
nuclear factor I/A
chr3_-_80802789 33.275 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr4_-_64046925 33.060 ENSMUST00000107377.3
 Tnc
tenascin C
chr15_-_66831625 28.916 ENSMUST00000164163.1
 Sla
src-like adaptor
chr11_+_98741805 26.783 ENSMUST00000064187.5
 Thra
thyroid hormone receptor alpha
chr12_+_29528382 26.198 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr18_-_42899470 25.715 ENSMUST00000120632.1
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr18_-_42899294 25.608 ENSMUST00000117687.1
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr2_+_124610573 25.109 ENSMUST00000103239.3
ENSMUST00000103240.2
 Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr11_-_69605829 23.604 ENSMUST00000047889.6
 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr11_+_98741871 21.797 ENSMUST00000103139.4
 Thra
thyroid hormone receptor alpha
chr11_+_58954675 21.752 ENSMUST00000047697.5
ENSMUST00000108817.3
 Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr11_+_57011945 21.429 ENSMUST00000094179.4
 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr11_+_57011798 21.347 ENSMUST00000036315.9
 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr8_+_118283719 20.353 ENSMUST00000117160.1
 Cdh13
cadherin 13
chr14_-_79771305 20.275 ENSMUST00000039568.5
 Pcdh8
protocadherin 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 127 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 106.1 GO:0006342 chromatin silencing(GO:0006342)
4.9 68.6 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
6.5 64.9 GO:0042118 endothelial cell activation(GO:0042118)
2.2 63.9 GO:0060074 synapse maturation(GO:0060074)
0.3 58.6 GO:0031032 actomyosin structure organization(GO:0031032)
7.3 51.3 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
1.4 49.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
16.2 48.6 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.6 48.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
2.1 43.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
2.5 43.1 GO:0021542 dentate gyrus development(GO:0021542)
1.4 42.8 GO:0045838 positive regulation of membrane potential(GO:0045838)
2.7 38.0 GO:0045161 neuronal ion channel clustering(GO:0045161)
7.6 37.8 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
8.3 33.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
2.2 25.9 GO:0002227 innate immune response in mucosa(GO:0002227)
1.0 25.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
5.9 23.6 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
1.8 21.8 GO:0070914 UV-damage excision repair(GO:0070914)
5.1 20.4 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 69.1 GO:0000790 nuclear chromatin(GO:0000790)
0.8 52.2 GO:0042734 presynaptic membrane(GO:0042734)
2.7 51.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.5 49.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.9 46.2 GO:0044295 axonal growth cone(GO:0044295)
7.1 42.8 GO:0044308 axonal spine(GO:0044308)
1.9 37.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 36.2 GO:0005739 mitochondrion(GO:0005739)
2.1 35.9 GO:0032279 asymmetric synapse(GO:0032279)
0.1 34.7 GO:0015629 actin cytoskeleton(GO:0015629)
2.1 33.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 32.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 30.4 GO:0031225 anchored component of membrane(GO:0031225)
0.8 30.3 GO:0000786 nucleosome(GO:0000786)
0.1 27.0 GO:0005768 endosome(GO:0005768)
3.4 23.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4 20.3 GO:0045171 intercellular bridge(GO:0045171)
1.6 20.2 GO:0097449 astrocyte projection(GO:0097449)
0.4 18.3 GO:0034707 chloride channel complex(GO:0034707)
0.2 18.3 GO:0043195 terminal bouton(GO:0043195)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 89 entries
Log-likelihood per target Total log-likelihoodTermDescription
10.9 76.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
16.2 64.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
3.7 51.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
16.2 48.6 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.7 47.2 GO:0005262 calcium channel activity(GO:0005262)
2.9 38.0 GO:0004385 guanylate kinase activity(GO:0004385)
3.2 37.8 GO:0097109 neuroligin family protein binding(GO:0097109)
1.0 35.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 34.1 GO:0003779 actin binding(GO:0003779)
5.5 33.1 GO:0045545 syndecan binding(GO:0045545)
0.7 27.3 GO:0005246 calcium channel regulator activity(GO:0005246)
2.4 23.6 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.2 21.2 GO:0030674 protein binding, bridging(GO:0030674)
4.1 20.4 GO:0055100 adiponectin binding(GO:0055100)
6.7 20.2 GO:0031687 A2A adenosine receptor binding(GO:0031687)
6.1 18.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.6 18.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
2.5 17.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 16.5 GO:0017022 myosin binding(GO:0017022)
0.8 15.4 GO:0001222 transcription corepressor binding(GO:0001222)