Motif ID: Pou6f2_Pou4f2

Z-value: 0.703

Transcription factors associated with Pou6f2_Pou4f2:

Gene SymbolEntrez IDGene Name
Pou4f2 ENSMUSG00000031688.3 Pou4f2
Pou6f2 ENSMUSG00000009734.11 Pou6f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou4f2mm10_v2_chr8_-_78436640_784366490.211.1e-01Click!
Pou6f2mm10_v2_chr13_-_18382041_183820410.162.1e-01Click!


Activity profile for motif Pou6f2_Pou4f2.

activity profile for motif Pou6f2_Pou4f2


Sorted Z-values histogram for motif Pou6f2_Pou4f2

Sorted Z-values for motif Pou6f2_Pou4f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou6f2_Pou4f2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 108 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_31949571 8.131 ENSMUST00000064016.5
 Gpr17
G protein-coupled receptor 17
chr2_+_109917639 7.624 ENSMUST00000046548.7
ENSMUST00000111037.2
 Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr6_+_63255971 7.033 ENSMUST00000159561.1
ENSMUST00000095852.3
 Grid2

glutamate receptor, ionotropic, delta 2

chr13_-_56296551 6.215 ENSMUST00000021970.9
 Cxcl14
chemokine (C-X-C motif) ligand 14
chr12_-_56535047 4.604 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr13_-_81570640 4.480 ENSMUST00000109565.2
 Gpr98
G protein-coupled receptor 98
chr5_-_62766153 4.323 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_-_49636847 4.100 ENSMUST00000032717.6
 Dbx1
developing brain homeobox 1
chr14_+_27039001 4.064 ENSMUST00000035336.3
 Il17rd
interleukin 17 receptor D
chr10_+_99263224 3.933 ENSMUST00000020118.4
 Dusp6
dual specificity phosphatase 6
chr5_-_62765618 3.709 ENSMUST00000159470.1
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_49564262 3.224 ENSMUST00000057610.6
 Daam2
dishevelled associated activator of morphogenesis 2
chr10_-_70655934 3.101 ENSMUST00000162144.1
ENSMUST00000162793.1
 Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like

chr1_-_72874877 3.056 ENSMUST00000027377.8
 Igfbp5
insulin-like growth factor binding protein 5
chr4_+_117849193 3.028 ENSMUST00000132043.2
ENSMUST00000169990.1
 Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr4_+_117849361 2.929 ENSMUST00000163288.1
 Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr1_+_172341197 2.706 ENSMUST00000056136.3
 Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr19_+_3323301 2.535 ENSMUST00000025835.4
 Cpt1a
carnitine palmitoyltransferase 1a, liver
chr8_-_92355764 2.328 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
 4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr6_+_88724828 2.287 ENSMUST00000089449.2
 Mgll
monoglyceride lipase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 8.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
2.5 7.6 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.6 7.6 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.5 7.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
2.1 6.2 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
2.0 6.0 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 5.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.3 4.8 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
1.5 4.6 GO:0021759 globus pallidus development(GO:0021759)
1.3 3.9 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.6 3.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 3.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.4 3.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.9 2.7 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.2 2.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 2.4 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 2.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 2.1 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.3 2.0 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 1.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.4 GO:0005667 transcription factor complex(GO:0005667)
0.2 7.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 6.0 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 4.4 GO:0098793 presynapse(GO:0098793)
0.3 3.9 GO:0043196 varicosity(GO:0043196)
0.8 3.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.2 2.7 GO:0097449 astrocyte projection(GO:0097449)
0.1 2.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.4 2.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.4 1.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.7 GO:0097542 ciliary tip(GO:0097542)
0.0 0.5 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 16.5 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.2 8.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 7.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.6 7.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.3 7.0 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
1.1 6.6 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 6.2 GO:0008009 chemokine activity(GO:0008009)
0.0 4.9 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.4 4.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
1.4 4.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 3.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 3.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.5 3.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.4 3.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.9 2.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 2.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 2.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.5 2.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.4 2.0 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.1 1.9 GO:0003785 actin monomer binding(GO:0003785)