Motif ID: Ppara

Z-value: 2.254


Transcription factors associated with Ppara:

Gene SymbolEntrez IDGene Name
Ppara ENSMUSG00000022383.7 Ppara



Activity profile for motif Ppara.

activity profile for motif Ppara


Sorted Z-values histogram for motif Ppara

Sorted Z-values for motif Ppara



Network of associatons between targets according to the STRING database.



First level regulatory network of Ppara

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_35910032 30.801 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
 Atat1




alpha tubulin acetyltransferase 1




chr15_-_66801577 26.355 ENSMUST00000168589.1
 Sla
src-like adaptor
chr17_-_35909626 26.038 ENSMUST00000141132.1
 Atat1
alpha tubulin acetyltransferase 1
chr2_+_170731807 24.188 ENSMUST00000029075.4
 Dok5
docking protein 5
chr12_+_61523889 24.102 ENSMUST00000119481.1
ENSMUST00000055815.7
 Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr3_+_95164306 23.563 ENSMUST00000107217.1
ENSMUST00000168321.1
 Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr8_+_124793013 21.596 ENSMUST00000167588.1
 Trim67
tripartite motif-containing 67
chr8_+_124793061 20.981 ENSMUST00000041106.7
 Trim67
tripartite motif-containing 67
chr8_-_84773381 20.801 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr5_+_117781017 20.319 ENSMUST00000138579.2
 Nos1
nitric oxide synthase 1, neuronal
chr5_+_35056813 20.156 ENSMUST00000101298.2
ENSMUST00000114270.1
ENSMUST00000133381.1
 Dok7


docking protein 7


chr11_+_67586520 20.094 ENSMUST00000108682.2
 Gas7
growth arrest specific 7
chr11_-_6065538 20.019 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr7_-_25005895 19.860 ENSMUST00000102858.3
ENSMUST00000080882.6
 Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr13_-_9878998 19.462 ENSMUST00000063093.9
 Chrm3
cholinergic receptor, muscarinic 3, cardiac
chr11_-_98329641 19.459 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr15_+_80091320 19.280 ENSMUST00000009728.6
ENSMUST00000009727.5
 Syngr1

synaptogyrin 1

chr7_-_141429351 18.787 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
 Cend1


cell cycle exit and neuronal differentiation 1


chr7_-_141429433 18.749 ENSMUST00000124444.1
 Cend1
cell cycle exit and neuronal differentiation 1
chr1_-_162478004 18.697 ENSMUST00000086074.5
ENSMUST00000070330.7
 Dnm3

dynamin 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 299 entries
Log-likelihood per target Total log-likelihoodTermDescription
18.9 56.8 GO:0071929 alpha-tubulin acetylation(GO:0071929)
1.3 51.8 GO:0006376 mRNA splice site selection(GO:0006376)
4.6 41.8 GO:0071420 cellular response to histamine(GO:0071420)
1.6 40.4 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
12.5 37.5 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
1.2 37.1 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
3.9 31.5 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
1.2 30.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.8 28.3 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
1.3 25.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
1.4 25.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
3.0 24.4 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
2.4 24.2 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.2 23.2 GO:0030041 actin filament polymerization(GO:0030041)
1.6 20.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
5.1 20.3 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
2.9 20.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
6.7 20.0 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
4.9 19.6 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
6.5 19.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 116 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 87.4 GO:0098794 postsynapse(GO:0098794)
0.0 58.2 GO:0016021 integral component of membrane(GO:0016021)
9.5 56.8 GO:0097427 microtubule bundle(GO:0097427)
1.0 47.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 39.7 GO:0045202 synapse(GO:0045202)
3.9 38.6 GO:0044327 dendritic spine head(GO:0044327)
2.1 37.5 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 30.7 GO:0005884 actin filament(GO:0005884)
0.4 29.7 GO:0031594 neuromuscular junction(GO:0031594)
0.5 28.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.6 27.4 GO:0042734 presynaptic membrane(GO:0042734)
1.3 24.9 GO:0032279 asymmetric synapse(GO:0032279)
0.2 24.6 GO:0030427 site of polarized growth(GO:0030427)
1.2 24.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 24.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 21.9 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.7 21.2 GO:0051233 spindle midzone(GO:0051233)
0.4 20.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
1.8 20.3 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.9 18.0 GO:0030673 axolemma(GO:0030673)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 225 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 60.5 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
1.0 47.9 GO:0005158 insulin receptor binding(GO:0005158)
2.1 35.6 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
5.4 32.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.8 31.6 GO:0035613 RNA stem-loop binding(GO:0035613)
1.1 30.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.7 29.3 GO:0004890 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
1.0 28.3 GO:0030215 semaphorin receptor binding(GO:0030215)
3.1 24.6 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
2.0 24.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.5 24.1 GO:0070888 E-box binding(GO:0070888)
0.7 23.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.1 22.7 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.6 22.4 GO:0050699 WW domain binding(GO:0050699)
0.1 22.1 GO:0051015 actin filament binding(GO:0051015)
6.8 20.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
1.8 20.2 GO:0038191 neuropilin binding(GO:0038191)
3.2 19.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
6.2 18.7 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
1.0 18.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)