Motif ID: Pparg_Rxrg

Z-value: 1.197

Transcription factors associated with Pparg_Rxrg:

Gene SymbolEntrez IDGene Name
Pparg ENSMUSG00000000440.6 Pparg
Rxrg ENSMUSG00000015843.4 Rxrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrgmm10_v2_chr1_+_167598384_167598411-0.066.4e-01Click!


Activity profile for motif Pparg_Rxrg.

activity profile for motif Pparg_Rxrg


Sorted Z-values histogram for motif Pparg_Rxrg

Sorted Z-values for motif Pparg_Rxrg



Network of associatons between targets according to the STRING database.



First level regulatory network of Pparg_Rxrg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103843154 14.182 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr12_+_109452833 12.887 ENSMUST00000056110.8
 Dlk1
delta-like 1 homolog (Drosophila)
chr3_+_87948666 12.287 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr7_+_4925802 11.807 ENSMUST00000057612.7
 Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chr11_-_77894096 8.802 ENSMUST00000017597.4
 Pipox
pipecolic acid oxidase
chr19_-_43912392 8.351 ENSMUST00000026209.4
 Dnmbp
dynamin binding protein
chr13_-_24761861 8.227 ENSMUST00000006898.3
ENSMUST00000110382.2
 Gmnn

geminin

chr2_+_126556128 7.383 ENSMUST00000141482.2
 Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr5_+_110286306 7.323 ENSMUST00000007296.5
ENSMUST00000112482.1
 Pole

polymerase (DNA directed), epsilon

chr6_-_124813065 6.498 ENSMUST00000149610.2
 Tpi1
triosephosphate isomerase 1
chr18_-_41951187 6.449 ENSMUST00000070949.4
 Prelid2
PRELI domain containing 2
chr6_+_34354119 6.377 ENSMUST00000038406.6
 Akr1b8
aldo-keto reductase family 1, member B8
chr5_+_64970069 6.367 ENSMUST00000031080.8
 Fam114a1
family with sequence similarity 114, member A1
chrX_+_73639414 6.249 ENSMUST00000019701.8
 Dusp9
dual specificity phosphatase 9
chr9_+_64117147 6.081 ENSMUST00000034969.7
 Lctl
lactase-like
chrX_-_106485214 5.752 ENSMUST00000039447.7
 Fndc3c1
fibronectin type III domain containing 3C1
chr1_-_66863265 5.745 ENSMUST00000027153.5
 Acadl
acyl-Coenzyme A dehydrogenase, long-chain
chr11_-_100354040 5.718 ENSMUST00000173630.1
 Hap1
huntingtin-associated protein 1
chr12_-_16800674 5.680 ENSMUST00000162112.1
 Greb1
gene regulated by estrogen in breast cancer protein
chr17_-_56290499 5.647 ENSMUST00000019726.6
 Plin3
perilipin 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 401 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.8 14.2 GO:0015671 oxygen transport(GO:0015671)
0.4 13.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
1.2 12.3 GO:0042573 retinoic acid metabolic process(GO:0042573)
2.4 11.8 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 11.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.9 11.1 GO:0006000 fructose metabolic process(GO:0006000)
1.5 10.5 GO:0016576 histone dephosphorylation(GO:0016576)
1.4 9.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.5 9.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
2.9 8.8 GO:0006553 lysine metabolic process(GO:0006553)
1.1 8.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 7.8 GO:0071229 cellular response to acid chemical(GO:0071229)
1.5 7.7 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
1.3 7.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
2.5 7.4 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
1.2 7.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 7.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 7.0 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.2 6.9 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 6.9 GO:0008203 cholesterol metabolic process(GO:0008203)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 178 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 20.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 19.6 GO:0005730 nucleolus(GO:0005730)
2.2 17.3 GO:0005833 hemoglobin complex(GO:0005833)
0.1 16.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 10.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 10.1 GO:0031012 extracellular matrix(GO:0031012)
1.2 9.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.7 9.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 8.9 GO:0005903 brush border(GO:0005903)
0.1 8.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
1.5 7.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.7 6.7 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 6.7 GO:0005667 transcription factor complex(GO:0005667)
0.2 6.6 GO:0034707 chloride channel complex(GO:0034707)
0.1 6.4 GO:0005811 lipid particle(GO:0005811)
0.1 6.2 GO:0005814 centriole(GO:0005814)
0.5 5.5 GO:0070531 BRCA1-A complex(GO:0070531)
0.4 5.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 5.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 5.3 GO:0005840 ribosome(GO:0005840)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 288 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.5 14.2 GO:0031721 hemoglobin alpha binding(GO:0031721)
1.5 13.4 GO:0001972 retinoic acid binding(GO:0001972)
0.6 12.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.6 11.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 11.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 11.2 GO:0016504 peptidase activator activity(GO:0016504)
0.1 11.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.9 10.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
1.1 10.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.7 9.8 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.2 9.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.2 9.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.8 9.0 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
2.2 8.8 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.7 8.7 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
1.4 8.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 8.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 7.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
2.5 7.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 7.3 GO:0070491 repressing transcription factor binding(GO:0070491)