Motif ID: Prop1

Z-value: 1.051


Transcription factors associated with Prop1:

Gene SymbolEntrez IDGene Name
Prop1 ENSMUSG00000044542.3 Prop1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prop1mm10_v2_chr11_-_50953745_509537680.123.6e-01Click!


Activity profile for motif Prop1.

activity profile for motif Prop1


Sorted Z-values histogram for motif Prop1

Sorted Z-values for motif Prop1



Network of associatons between targets according to the STRING database.



First level regulatory network of Prop1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_61804453 7.601 ENSMUST00000048934.8
Tbr1
T-box brain gene 1
chr14_-_40893222 6.791 ENSMUST00000096000.3
Sh2d4b
SH2 domain containing 4B
chr4_-_110292719 5.323 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr3_+_94377432 5.314 ENSMUST00000107292.1
Rorc
RAR-related orphan receptor gamma
chr3_+_94377505 4.630 ENSMUST00000098877.2
Rorc
RAR-related orphan receptor gamma
chr1_+_107511416 3.869 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr4_-_82505749 3.824 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr9_+_118478182 3.796 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr14_+_75455957 3.764 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr18_-_62741387 3.759 ENSMUST00000097557.3
Spink13
serine peptidase inhibitor, Kazal type 13
chr9_+_118478344 3.622 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr4_-_87806296 3.606 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr4_-_119492563 3.556 ENSMUST00000049994.7
Rimkla
ribosomal modification protein rimK-like family member A
chr16_-_45693658 3.481 ENSMUST00000114562.2
ENSMUST00000036617.7
Tmprss7

transmembrane serine protease 7

chr2_+_20737306 3.298 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr4_-_82505707 3.294 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr4_-_87806276 3.155 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr12_-_55014329 3.150 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr13_+_24327415 3.145 ENSMUST00000167746.1
Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr2_-_67194695 3.107 ENSMUST00000147939.1
Gm13598
predicted gene 13598

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 113 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 9.9 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.8 8.4 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.5 7.6 GO:0001661 conditioned taste aversion(GO:0001661) amygdala development(GO:0021764)
2.5 7.4 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.8 7.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.7 6.8 GO:0007379 segment specification(GO:0007379)
0.1 5.2 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 4.7 GO:0006284 base-excision repair(GO:0006284)
0.8 3.8 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.8 3.8 GO:0060467 negative regulation of fertilization(GO:0060467)
0.2 3.3 GO:0048706 embryonic skeletal system development(GO:0048706)
1.1 3.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
1.0 3.1 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.0 3.1 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.3 3.0 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 2.9 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.2 2.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.5 2.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 2.6 GO:0035315 hair cell differentiation(GO:0035315) auditory receptor cell differentiation(GO:0042491)
0.5 2.5 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.5 GO:0005730 nucleolus(GO:0005730)
0.4 8.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.3 7.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 6.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.4 5.3 GO:0042788 polysomal ribosome(GO:0042788)
0.7 4.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 4.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 4.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.1 3.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 3.2 GO:0070469 respiratory chain(GO:0070469)
0.6 3.1 GO:0008623 CHRAC(GO:0008623)
0.0 2.8 GO:0005814 centriole(GO:0005814)
0.3 2.7 GO:0071439 clathrin complex(GO:0071439)
0.1 2.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 2.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 2.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.1 GO:0030016 myofibril(GO:0030016)
0.1 1.9 GO:0031045 dense core granule(GO:0031045)
0.2 1.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 1.7 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.5 9.9 GO:0008142 oxysterol binding(GO:0008142)
0.1 8.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.3 8.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 8.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 7.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 7.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 5.3 GO:0017091 AU-rich element binding(GO:0017091)
0.6 5.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 5.2 GO:0005496 steroid binding(GO:0005496)
0.1 4.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 3.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 3.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
1.0 3.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 2.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.8 2.5 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.4 2.2 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 2.2 GO:0005507 copper ion binding(GO:0005507)
0.1 2.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.7 2.0 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 2.0 GO:0031489 myosin V binding(GO:0031489)