Motif ID: Rara

Z-value: 0.698


Transcription factors associated with Rara:

Gene SymbolEntrez IDGene Name
Rara ENSMUSG00000037992.10 Rara

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Raramm10_v2_chr11_+_98927785_989278180.453.6e-04Click!


Activity profile for motif Rara.

activity profile for motif Rara


Sorted Z-values histogram for motif Rara

Sorted Z-values for motif Rara



Network of associatons between targets according to the STRING database.



First level regulatory network of Rara

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_94875600 8.362 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr4_-_141599835 4.283 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
 Fblim1



filamin binding LIM protein 1



chr6_+_30723541 3.748 ENSMUST00000115127.1
 Mest
mesoderm specific transcript
chr17_+_34593388 3.408 ENSMUST00000174532.1
 Pbx2
pre B cell leukemia homeobox 2
chr11_+_98960412 3.191 ENSMUST00000107473.2
 Rara
retinoic acid receptor, alpha
chr14_-_16575456 2.369 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta
chr4_+_150853919 2.250 ENSMUST00000073600.2
 Errfi1
ERBB receptor feedback inhibitor 1
chr12_-_108893197 1.812 ENSMUST00000161154.1
ENSMUST00000161410.1
 Wars

tryptophanyl-tRNA synthetase

chr10_+_4611971 1.757 ENSMUST00000105590.1
ENSMUST00000067086.7
 Esr1

estrogen receptor 1 (alpha)

chr1_-_175692624 1.573 ENSMUST00000027809.7
 Opn3
opsin 3
chr12_+_87026564 1.571 ENSMUST00000110187.1
ENSMUST00000156162.1
 Tmem63c

transmembrane protein 63c

chr11_+_94629741 1.546 ENSMUST00000021239.6
 Lrrc59
leucine rich repeat containing 59
chr4_-_128609981 1.450 ENSMUST00000141040.1
ENSMUST00000147876.1
ENSMUST00000097877.2
 Zscan20


zinc finger and SCAN domains 20


chr3_-_36475688 1.419 ENSMUST00000029266.8
 Anxa5
annexin A5
chr14_+_55618023 1.406 ENSMUST00000002395.7
 Rec8
REC8 homolog (yeast)
chr11_-_5915124 1.383 ENSMUST00000109823.2
ENSMUST00000109822.1
 Gck

glucokinase

chr4_+_48045144 1.223 ENSMUST00000030025.3
 Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr2_+_26319741 1.218 ENSMUST00000066889.6
 Gpsm1
G-protein signalling modulator 1 (AGS3-like, C. elegans)
chr1_+_134037490 1.167 ENSMUST00000162779.1
 Fmod
fibromodulin
chr6_+_91157373 1.149 ENSMUST00000155007.1
 Hdac11
histone deacetylase 11
chr14_+_58070547 1.088 ENSMUST00000165526.1
 Fgf9
fibroblast growth factor 9
chr17_-_56133817 1.039 ENSMUST00000167545.1
 Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr2_+_5845243 1.035 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr8_+_106150359 1.013 ENSMUST00000034377.6
 Pla2g15
phospholipase A2, group XV
chr8_-_94876269 0.998 ENSMUST00000046461.7
 Dok4
docking protein 4
chr11_+_4986824 0.994 ENSMUST00000009234.9
ENSMUST00000109897.1
 Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr7_+_120635176 0.942 ENSMUST00000033176.5
 Uqcrc2
ubiquinol cytochrome c reductase core protein 2
chr5_+_135806859 0.916 ENSMUST00000126232.1
 Srrm3
serine/arginine repetitive matrix 3
chr5_-_114273702 0.915 ENSMUST00000144050.1
ENSMUST00000044790.5
 Foxn4

forkhead box N4

chr14_+_76488436 0.892 ENSMUST00000101618.2
 Tsc22d1
TSC22 domain family, member 1
chr7_-_141429351 0.873 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
 Cend1


cell cycle exit and neuronal differentiation 1


chr7_-_141429433 0.828 ENSMUST00000124444.1
 Cend1
cell cycle exit and neuronal differentiation 1
chr10_-_89257790 0.770 ENSMUST00000045601.7
 Ano4
anoctamin 4
chr2_+_5845017 0.721 ENSMUST00000026927.3
ENSMUST00000179748.1
 Nudt5

nudix (nucleoside diphosphate linked moiety X)-type motif 5

chr10_+_79910856 0.708 ENSMUST00000181321.1
 Gm26602
predicted gene, 26602
chr4_+_141444654 0.700 ENSMUST00000006377.6
 Zbtb17
zinc finger and BTB domain containing 17
chr11_-_97700327 0.651 ENSMUST00000018681.7
 Pcgf2
polycomb group ring finger 2
chr4_+_32238950 0.648 ENSMUST00000037416.6
 Bach2
BTB and CNC homology 2
chr4_-_152318458 0.636 ENSMUST00000170820.1
ENSMUST00000076183.5
 Rnf207

ring finger protein 207

chr3_-_54915867 0.629 ENSMUST00000070342.3
 Sertm1
serine rich and transmembrane domain containing 1
chr4_+_41348996 0.615 ENSMUST00000072866.5
ENSMUST00000108060.3
 Ubap1

ubiquitin-associated protein 1

chr2_+_169633517 0.589 ENSMUST00000109157.1
 Tshz2
teashirt zinc finger family member 2
chrX_+_74254736 0.582 ENSMUST00000096424.4
 Emd
emerin
chr9_-_109074049 0.577 ENSMUST00000161521.1
ENSMUST00000045011.2
 Atrip

ATR interacting protein

chr2_-_34754364 0.557 ENSMUST00000142436.1
ENSMUST00000113099.3
ENSMUST00000028224.8
 Gapvd1


GTPase activating protein and VPS9 domains 1


chr6_-_6217023 0.555 ENSMUST00000015256.8
 Slc25a13
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr2_-_5845164 0.517 ENSMUST00000043864.3
 Cdc123
cell division cycle 123
chr8_-_119778380 0.516 ENSMUST00000049156.5
 Tldc1
TBC/LysM associated domain containing 1
chr19_-_7241216 0.489 ENSMUST00000025675.9
 Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr2_+_181365384 0.486 ENSMUST00000108807.2
 Zgpat
zinc finger, CCCH-type with G patch domain
chr10_+_21993890 0.482 ENSMUST00000092673.4
 Sgk1
serum/glucocorticoid regulated kinase 1
chr6_+_18848571 0.477 ENSMUST00000056398.8
 Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr17_-_32388885 0.463 ENSMUST00000087703.5
ENSMUST00000170603.1
 Wiz

widely-interspaced zinc finger motifs

chr14_+_20674311 0.457 ENSMUST00000048657.8
 Sec24c
Sec24 related gene family, member C (S. cerevisiae)
chr3_+_152210458 0.445 ENSMUST00000166984.1
ENSMUST00000106121.1
 Fubp1

far upstream element (FUSE) binding protein 1

chr7_+_45873127 0.439 ENSMUST00000107718.1
 Kdelr1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chrX_+_74254782 0.419 ENSMUST00000119197.1
ENSMUST00000088313.4
 Emd

emerin

chr2_-_181365306 0.402 ENSMUST00000108808.1
ENSMUST00000170190.1
ENSMUST00000127988.1
 Arfrp1


ADP-ribosylation factor related protein 1


chr7_+_45872772 0.338 ENSMUST00000002855.5
ENSMUST00000107719.1
 Kdelr1

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

chrX_+_106187100 0.326 ENSMUST00000081593.6
 Pgk1
phosphoglycerate kinase 1
chr6_+_115601907 0.307 ENSMUST00000000449.7
 Mkrn2
makorin, ring finger protein, 2
chr2_-_5012716 0.227 ENSMUST00000027980.7
 Mcm10
minichromosome maintenance deficient 10 (S. cerevisiae)
chr2_+_131262469 0.226 ENSMUST00000150843.1
 Pank2
pantothenate kinase 2
chr5_+_53590215 0.205 ENSMUST00000037618.6
 Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chrX_-_75874536 0.189 ENSMUST00000033547.7
 Pls3
plastin 3 (T-isoform)
chr9_-_43105718 0.160 ENSMUST00000165665.1
 Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
chr1_-_36369173 0.148 ENSMUST00000010597.3
 Kansl3
KAT8 regulatory NSL complex subunit 3
chr4_-_46991842 0.115 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr10_+_19951055 0.103 ENSMUST00000152533.1
 Map3k5
mitogen-activated protein kinase kinase kinase 5
chr13_+_49421229 0.006 ENSMUST00000021817.8
 Ippk
inositol 1,3,4,5,6-pentakisphosphate 2-kinase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.7 2.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.6 1.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.6 8.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.6 1.7 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.5 1.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.5 2.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.5 1.4 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.4 1.8 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.4 1.2 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.4 1.4 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.3 4.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.3 0.8 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.2 0.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.2 0.6 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.1 1.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 3.7 GO:0010883 regulation of lipid storage(GO:0010883)
0.1 0.6 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 1.4 GO:0007141 male meiosis I(GO:0007141)
0.1 1.8 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.1 0.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 3.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.2 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.9 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 1.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.1 0.5 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 1.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.7 GO:0007398 ectoderm development(GO:0007398)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.6 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:1904251 regulation of bile acid metabolic process(GO:1904251)
0.0 1.2 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.0 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 1.1 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.4 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 1.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.1 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0000798 nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991)
0.2 0.5 GO:0031417 NatC complex(GO:0031417)
0.1 0.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.4 GO:0045180 basal cortex(GO:0045180)
0.1 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.7 GO:0001739 sex chromatin(GO:0001739)
0.1 1.0 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 3.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 1.3 GO:0014704 intercalated disc(GO:0014704)
0.0 2.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 4.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.0 3.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.6 1.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.5 1.6 GO:0009881 photoreceptor activity(GO:0009881)
0.4 3.2 GO:0001972 retinoic acid binding(GO:0001972)
0.3 4.3 GO:0031005 filamin binding(GO:0031005)
0.2 1.4 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.2 1.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.2 0.8 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 2.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 3.7 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.1 1.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 1.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.7 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 1.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.0 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 2.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 14.8 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.2 GO:0008201 heparin binding(GO:0008201)