Motif ID: Rbpj

Z-value: 0.793


Transcription factors associated with Rbpj:

Gene SymbolEntrez IDGene Name
Rbpj ENSMUSG00000039191.6 Rbpj

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rbpjmm10_v2_chr5_+_53590453_535905740.374.2e-03Click!


Activity profile for motif Rbpj.

activity profile for motif Rbpj


Sorted Z-values histogram for motif Rbpj

Sorted Z-values for motif Rbpj



Network of associatons between targets according to the STRING database.



First level regulatory network of Rbpj

PNG image of the network

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Top targets:


Showing 1 to 20 of 161 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_30842765 5.377 ENSMUST00000019924.8
Hey2
hairy/enhancer-of-split related with YRPW motif 2
chr11_+_78324200 5.143 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr11_-_102579461 3.749 ENSMUST00000107081.1
Gm11627
predicted gene 11627
chr4_+_154960915 3.550 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr2_+_59612034 2.650 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr4_+_156203292 2.643 ENSMUST00000105140.2
AW011738
expressed sequence AW011738
chrX_+_139684980 2.623 ENSMUST00000096313.3
Tbc1d8b
TBC1 domain family, member 8B
chr19_+_53140430 2.551 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr5_-_77115145 2.506 ENSMUST00000081964.5
Hopx
HOP homeobox
chr18_+_34625009 2.217 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr2_+_105668935 2.126 ENSMUST00000142772.1
Pax6
paired box gene 6
chr9_-_26806384 2.064 ENSMUST00000162702.1
ENSMUST00000040398.7
ENSMUST00000066560.6
Glb1l2


galactosidase, beta 1-like 2


chr6_+_29694204 2.056 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr2_+_105668888 1.931 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr18_+_34624621 1.919 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr15_-_86033777 1.862 ENSMUST00000016172.7
Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr9_+_123478693 1.844 ENSMUST00000026269.2
Limd1
LIM domains containing 1
chr12_-_80260091 1.818 ENSMUST00000167327.1
Actn1
actinin, alpha 1
chr11_+_63133068 1.777 ENSMUST00000108700.1
Pmp22
peripheral myelin protein 22
chr6_-_5298455 1.766 ENSMUST00000057792.8
Pon2
paraoxonase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 5.4 GO:0003195 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.5 5.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.8 4.1 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918)
0.2 4.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 3.6 GO:0090630 activation of GTPase activity(GO:0090630)
1.2 3.5 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.4 3.3 GO:0051639 actin filament network formation(GO:0051639)
1.0 2.9 GO:0014028 notochord formation(GO:0014028)
0.1 2.6 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 2.6 GO:0042493 response to drug(GO:0042493)
0.4 2.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 2.5 GO:0032060 bleb assembly(GO:0032060)
0.2 2.4 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 2.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.5 2.0 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.6 1.9 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.4 1.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 1.8 GO:0009636 response to toxic substance(GO:0009636)
0.6 1.7 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.1 1.7 GO:0043171 peptide catabolic process(GO:0043171)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.6 GO:0030424 axon(GO:0030424)
0.4 7.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 5.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 4.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 4.1 GO:0005871 kinesin complex(GO:0005871)
0.8 3.3 GO:0032127 dense core granule membrane(GO:0032127)
0.0 2.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.3 2.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.8 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 1.8 GO:0043218 compact myelin(GO:0043218)
0.4 1.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 1.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 1.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.4 1.1 GO:0034455 t-UTP complex(GO:0034455)
0.1 1.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 0.8 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 5.4 GO:0035939 microsatellite binding(GO:0035939)
0.9 5.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.4 4.1 GO:0003680 AT DNA binding(GO:0003680)
0.1 4.1 GO:0003777 microtubule motor activity(GO:0003777)
0.1 3.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 3.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 3.3 GO:0017166 vinculin binding(GO:0017166)
0.0 2.4 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 2.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.5 2.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 2.1 GO:0005080 protein kinase C binding(GO:0005080)
0.3 2.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 1.9 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.6 1.8 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.4 1.8 GO:0004064 arylesterase activity(GO:0004064)
0.4 1.7 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.3 1.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 1.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.5 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 1.5 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)