Motif ID: Rela_Rel_Nfkb1
Z-value: 1.369



Transcription factors associated with Rela_Rel_Nfkb1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nfkb1 | ENSMUSG00000028163.11 | Nfkb1 |
Rel | ENSMUSG00000020275.8 | Rel |
Rela | ENSMUSG00000024927.7 | Rela |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nfkb1 | mm10_v2_chr3_-_135691512_135691564 | 0.88 | 9.6e-20 | Click! |
Rela | mm10_v2_chr19_+_5637475_5637486 | -0.03 | 8.2e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 251 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.8 | 18.9 | GO:0015671 | oxygen transport(GO:0015671) |
2.1 | 14.4 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
0.7 | 13.9 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.2 | 13.0 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845) |
1.2 | 12.5 | GO:0008063 | Toll signaling pathway(GO:0008063) |
2.0 | 12.1 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
0.9 | 10.3 | GO:0048484 | enteric nervous system development(GO:0048484) |
0.1 | 9.4 | GO:0044344 | cellular response to fibroblast growth factor stimulus(GO:0044344) |
0.8 | 9.3 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
0.1 | 9.3 | GO:0007519 | skeletal muscle tissue development(GO:0007519) |
0.6 | 8.7 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
0.2 | 8.7 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
0.4 | 7.0 | GO:0002467 | germinal center formation(GO:0002467) |
0.3 | 7.0 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
1.1 | 6.9 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
2.3 | 6.8 | GO:0070103 | regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104) |
0.9 | 6.6 | GO:0000022 | mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256) |
1.3 | 6.4 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
1.5 | 6.2 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
0.2 | 6.2 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 133 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.9 | 20.2 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
2.4 | 18.9 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.2 | 18.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.6 | 13.0 | GO:0043657 | host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657) |
0.3 | 12.2 | GO:0043034 | costamere(GO:0043034) |
0.7 | 10.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.0 | 9.5 | GO:0005667 | transcription factor complex(GO:0005667) |
0.1 | 9.2 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
1.1 | 8.9 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.6 | 8.3 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.3 | 8.3 | GO:0002102 | podosome(GO:0002102) |
0.1 | 8.0 | GO:0000922 | spindle pole(GO:0000922) |
0.0 | 8.0 | GO:0043209 | myelin sheath(GO:0043209) |
0.6 | 6.7 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
2.2 | 6.5 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
0.1 | 6.5 | GO:0005882 | intermediate filament(GO:0005882) |
0.8 | 6.4 | GO:0098536 | deuterosome(GO:0098536) |
1.3 | 5.3 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
1.0 | 5.1 | GO:0031523 | Myb complex(GO:0031523) |
0.0 | 4.7 | GO:0000118 | histone deacetylase complex(GO:0000118) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 169 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 35.5 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
0.2 | 22.3 | GO:0005178 | integrin binding(GO:0005178) |
4.7 | 18.9 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
0.1 | 17.2 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 13.6 | GO:0044822 | poly(A) RNA binding(GO:0044822) |
1.0 | 12.5 | GO:0031996 | thioesterase binding(GO:0031996) |
1.2 | 12.1 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.3 | 11.1 | GO:0005109 | frizzled binding(GO:0005109) |
3.6 | 10.7 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
0.2 | 9.7 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
0.0 | 9.0 | GO:0005509 | calcium ion binding(GO:0005509) |
0.1 | 8.8 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
0.1 | 8.6 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.6 | 8.3 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.5 | 7.7 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.2 | 7.4 | GO:0042805 | actinin binding(GO:0042805) |
0.2 | 7.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.4 | 6.5 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.5 | 6.0 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
2.0 | 5.9 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924) |