Motif ID: Rest

Z-value: 4.575


Transcription factors associated with Rest:

Gene SymbolEntrez IDGene Name
Rest ENSMUSG00000029249.9 Rest

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Restmm10_v2_chr5_+_77266196_77266232-0.706.7e-10Click!


Activity profile for motif Rest.

activity profile for motif Rest


Sorted Z-values histogram for motif Rest

Sorted Z-values for motif Rest



Network of associatons between targets according to the STRING database.



First level regulatory network of Rest

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_23890805 140.213 ENSMUST00000004480.3
 Sst
somatostatin
chrX_-_73869804 133.383 ENSMUST00000066576.5
ENSMUST00000114430.1
 L1cam

L1 cell adhesion molecule

chr19_+_42255704 116.707 ENSMUST00000087123.5
 Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr18_-_31447383 88.715 ENSMUST00000025110.3
 Syt4
synaptotagmin IV
chr15_-_76521902 83.526 ENSMUST00000164703.1
ENSMUST00000096365.3
 Scrt1

scratch homolog 1, zinc finger protein (Drosophila)

chr2_+_153031852 76.310 ENSMUST00000037235.6
 Xkr7
X Kell blood group precursor related family member 7 homolog
chr11_-_35798884 75.397 ENSMUST00000160726.2
 Fbll1
fibrillarin-like 1
chr11_+_80477015 67.459 ENSMUST00000053413.10
ENSMUST00000147694.1
 Cdk5r1

cyclin-dependent kinase 5, regulatory subunit 1 (p35)

chr6_-_121473630 66.394 ENSMUST00000046373.5
 Iqsec3
IQ motif and Sec7 domain 3
chr11_+_77930800 61.825 ENSMUST00000093995.3
ENSMUST00000000646.7
 Sez6

seizure related gene 6

chr1_+_34579693 61.383 ENSMUST00000052670.8
 Amer3
APC membrane recruitment 3
chr9_+_40269430 59.616 ENSMUST00000171835.2
 Scn3b
sodium channel, voltage-gated, type III, beta
chr3_-_80802789 55.929 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr9_+_40269202 53.704 ENSMUST00000114956.3
ENSMUST00000049941.5
 Scn3b

sodium channel, voltage-gated, type III, beta

chr2_+_155775333 52.710 ENSMUST00000029141.5
 Mmp24
matrix metallopeptidase 24
chr9_+_40269273 50.719 ENSMUST00000176185.1
 Scn3b
sodium channel, voltage-gated, type III, beta
chr4_-_129121234 49.317 ENSMUST00000030572.3
 Hpca
hippocalcin
chr12_-_112511136 49.136 ENSMUST00000066791.5
 Tmem179
transmembrane protein 179
chr7_-_81493725 47.831 ENSMUST00000119121.1
 Ap3b2
adaptor-related protein complex 3, beta 2 subunit
chr12_+_102554966 47.726 ENSMUST00000021610.5
 Chga
chromogranin A
chr7_+_27653906 47.532 ENSMUST00000008088.7
 Ttc9b
tetratricopeptide repeat domain 9B
chr4_+_101550411 47.526 ENSMUST00000094953.4
ENSMUST00000106933.1
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr3_-_89764581 46.543 ENSMUST00000029562.3
 Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr2_+_132781278 45.859 ENSMUST00000028826.3
 Chgb
chromogranin B
chr11_+_74619594 45.113 ENSMUST00000100866.2
 E130309D14Rik
RIKEN cDNA E130309D14 gene
chr2_-_25319095 44.859 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
 Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr7_-_81493883 44.766 ENSMUST00000082090.7
 Ap3b2
adaptor-related protein complex 3, beta 2 subunit
chr5_-_121009510 44.700 ENSMUST00000079204.5
 Rph3a
rabphilin 3A
chr2_-_181314500 41.599 ENSMUST00000103045.3
 Stmn3
stathmin-like 3
chr9_+_108826320 39.214 ENSMUST00000024238.5
 Celsr3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chrX_-_20920911 37.288 ENSMUST00000081893.6
ENSMUST00000115345.1
 Syn1

synapsin I

chr17_-_91092715 37.246 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
 Nrxn1


neurexin I


chr12_+_102949450 35.350 ENSMUST00000179002.1
 Unc79
unc-79 homolog (C. elegans)
chrX_+_7638674 34.472 ENSMUST00000128890.1
 Syp
synaptophysin
chr15_-_76722161 32.481 ENSMUST00000049956.4
 Lrrc24
leucine rich repeat containing 24
chr7_-_27396542 32.388 ENSMUST00000108363.1
 Sptbn4
spectrin beta, non-erythrocytic 4
chr5_-_116591811 32.297 ENSMUST00000076124.5
 Srrm4
serine/arginine repetitive matrix 4
chr5_+_137030275 31.419 ENSMUST00000041543.8
 Vgf
VGF nerve growth factor inducible
chr13_-_54749627 30.846 ENSMUST00000099506.1
 Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr6_+_8948608 28.920 ENSMUST00000160300.1
 Nxph1
neurexophilin 1
chr7_+_51621830 28.848 ENSMUST00000032710.5
 Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr7_+_122671401 28.667 ENSMUST00000182095.1
 Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr7_+_122671378 27.784 ENSMUST00000182563.1
 Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr11_+_102393403 26.782 ENSMUST00000107105.2
ENSMUST00000107102.1
ENSMUST00000107103.1
ENSMUST00000006750.7
 Rundc3a



RUN domain containing 3A



chr2_-_27142429 26.559 ENSMUST00000151224.2
 Fam163b
family with sequence similarity 163, member B
chr1_-_84696182 26.398 ENSMUST00000049126.6
 Dner
delta/notch-like EGF-related receptor
chr9_+_59578192 25.486 ENSMUST00000118549.1
ENSMUST00000034840.3
 Celf6

CUGBP, Elav-like family member 6

chr17_+_28575718 25.361 ENSMUST00000080780.6
 Lhfpl5
lipoma HMGIC fusion partner-like 5
chr9_-_57467985 24.909 ENSMUST00000046587.6
 Scamp5
secretory carrier membrane protein 5
chr13_-_54749849 23.695 ENSMUST00000135343.1
 Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr11_-_3774706 23.559 ENSMUST00000155197.1
 Osbp2
oxysterol binding protein 2
chr12_-_84698769 22.435 ENSMUST00000095550.2
 Syndig1l
synapse differentiation inducing 1 like
chr2_-_25319187 21.494 ENSMUST00000114312.1
 Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr1_+_81077274 19.965 ENSMUST00000068275.5
ENSMUST00000113494.2
 Nyap2

neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2

chr6_+_117168535 19.857 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
 Cxcl12


chemokine (C-X-C motif) ligand 12


chr13_+_54371340 19.588 ENSMUST00000026985.8
 Cplx2
complexin 2
chr17_-_83631892 16.157 ENSMUST00000051482.1
 Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr1_+_81077204 14.106 ENSMUST00000123720.1
 Nyap2
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr15_-_11037968 13.969 ENSMUST00000058007.5
 Rxfp3
relaxin family peptide receptor 3
chr17_-_72603709 13.337 ENSMUST00000086639.4
 Alk
anaplastic lymphoma kinase
chr12_-_70347536 12.291 ENSMUST00000110520.2
ENSMUST00000110522.2
ENSMUST00000167755.1
 Trim9


tripartite motif-containing 9


chr19_-_45046614 11.835 ENSMUST00000145391.1
 Pdzd7
PDZ domain containing 7
chr9_-_22085391 11.648 ENSMUST00000179422.1
ENSMUST00000098937.3
ENSMUST00000177967.1
ENSMUST00000180180.1
 Ecsit



ECSIT homolog (Drosophila)



chr7_+_63444741 10.237 ENSMUST00000058476.7
 Otud7a
OTU domain containing 7A
chr13_-_56895737 9.499 ENSMUST00000022023.6
ENSMUST00000109871.1
 Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr2_+_22622183 8.587 ENSMUST00000028123.3
 Gad2
glutamic acid decarboxylase 2
chr1_-_34579613 8.167 ENSMUST00000062557.3
 1700101I19Rik
RIKEN cDNA 1700101I19 gene
chr16_-_37384915 7.490 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
 Stxbp5l



syntaxin binding protein 5-like



chr13_-_105054895 7.488 ENSMUST00000063551.5
 Rgs7bp
regulator of G-protein signalling 7 binding protein
chr1_-_193035651 7.480 ENSMUST00000016344.7
 Syt14
synaptotagmin XIV
chr9_+_104569671 6.655 ENSMUST00000057742.8
 Cpne4
copine IV
chr2_+_152143552 6.400 ENSMUST00000089112.5
 Tcf15
transcription factor 15
chr4_+_15881255 6.360 ENSMUST00000029876.1
 Calb1
calbindin 1
chr13_-_23991158 6.297 ENSMUST00000021770.7
 Scgn
secretagogin, EF-hand calcium binding protein
chr4_+_129136948 6.151 ENSMUST00000102600.3
 Fndc5
fibronectin type III domain containing 5
chr2_-_180104463 5.421 ENSMUST00000056480.3
 Hrh3
histamine receptor H3
chr9_+_122117375 5.299 ENSMUST00000118886.1
 Snrk
SNF related kinase
chr9_+_104569754 5.023 ENSMUST00000077190.6
 Cpne4
copine IV
chr9_+_40873981 4.741 ENSMUST00000067375.3
 Bsx
brain specific homeobox
chr9_+_122117258 3.773 ENSMUST00000146832.1
ENSMUST00000139181.1
 Snrk

SNF related kinase

chr12_+_113140198 3.743 ENSMUST00000084882.4
 Crip2
cysteine rich protein 2
chr2_-_92401237 2.977 ENSMUST00000050312.2
 Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
chr19_+_22139028 2.897 ENSMUST00000099569.2
ENSMUST00000087576.4
ENSMUST00000074770.5
 Trpm3


transient receptor potential cation channel, subfamily M, member 3


chr8_+_18846251 2.434 ENSMUST00000149565.1
ENSMUST00000033847.4
 Agpat5

1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)

chr2_+_157456917 1.505 ENSMUST00000109529.1
 Src
Rous sarcoma oncogene
chr8_+_69088646 1.055 ENSMUST00000006435.7
 Atp6v1b2
ATPase, H+ transporting, lysosomal V1 subunit B2
chr9_+_122117338 0.769 ENSMUST00000120173.1
ENSMUST00000134949.1
ENSMUST00000119215.1
 Snrk


SNF related kinase



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
33.5 133.8 GO:0021586 pons maturation(GO:0021586)
18.2 164.0 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
16.4 49.3 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
15.9 47.7 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
15.5 46.5 GO:0060084 conditioned taste aversion(GO:0001661) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084)
15.1 75.4 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
13.9 41.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
13.3 133.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
11.5 34.5 GO:0038003 opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474)
11.2 101.0 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
7.4 37.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
7.4 44.2 GO:0072318 clathrin coat disassembly(GO:0072318)
6.5 39.2 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
5.4 32.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
5.0 19.9 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
4.8 52.7 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
4.6 92.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
3.9 19.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
3.5 35.3 GO:0048149 behavioral response to ethanol(GO:0048149)
2.9 61.8 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
2.9 55.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
2.7 66.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
2.6 31.4 GO:0043084 penile erection(GO:0043084)
2.5 37.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
2.4 26.4 GO:0007220 Notch receptor processing(GO:0007220)
2.4 56.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
2.1 8.6 GO:0006538 glutamate catabolic process(GO:0006538)
2.0 10.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
1.9 26.8 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
1.9 83.5 GO:2001222 regulation of neuron migration(GO:2001222)
1.8 5.4 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
1.8 24.9 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
1.4 28.8 GO:0001504 neurotransmitter uptake(GO:0001504)
1.4 44.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
1.2 25.5 GO:0071625 vocalization behavior(GO:0071625)
1.1 14.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.9 6.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.9 6.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.7 47.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.7 32.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.5 1.5 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.5 3.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.5 6.4 GO:0007614 short-term memory(GO:0007614)
0.5 32.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.4 9.5 GO:0006828 manganese ion transport(GO:0006828)
0.4 37.3 GO:0099643 neurotransmitter secretion(GO:0007269) presynaptic process involved in chemical synaptic transmission(GO:0099531) signal release from synapse(GO:0099643)
0.4 4.7 GO:0060056 mammary gland involution(GO:0060056)
0.3 34.1 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.2 53.1 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.2 11.6 GO:0051341 regulation of oxidoreductase activity(GO:0051341)
0.2 140.2 GO:0030334 regulation of cell migration(GO:0030334)
0.2 23.6 GO:0007286 spermatid development(GO:0007286)
0.2 7.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.2 13.3 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 16.2 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.1 7.5 GO:0006906 vesicle fusion(GO:0006906)
0.0 6.3 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 22.4 GO:0009607 response to biotic stimulus(GO:0009607)
0.0 1.1 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 2.4 GO:0006639 neutral lipid metabolic process(GO:0006638) acylglycerol metabolic process(GO:0006639)
0.0 12.6 GO:0031175 neuron projection development(GO:0031175)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
22.5 67.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
16.6 66.4 GO:0044307 dendritic branch(GO:0044307)
10.3 164.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
9.5 47.7 GO:0042583 chromaffin granule(GO:0042583)
9.4 75.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
8.4 92.6 GO:1904115 axon cytoplasm(GO:1904115)
5.9 88.7 GO:0031045 dense core granule(GO:0031045)
5.4 32.4 GO:0008091 spectrin(GO:0008091)
5.1 25.4 GO:0032426 stereocilium tip(GO:0032426)
4.9 49.3 GO:0044327 dendritic spine head(GO:0044327)
4.9 19.6 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
4.6 209.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
4.2 46.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
3.9 11.8 GO:0002141 stereocilia ankle link(GO:0002141)
2.6 136.4 GO:0044295 axonal growth cone(GO:0044295)
2.3 66.4 GO:0060077 inhibitory synapse(GO:0060077)
2.2 85.4 GO:0097440 apical dendrite(GO:0097440)
2.2 69.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
1.4 56.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.7 31.4 GO:0030667 secretory granule membrane(GO:0030667)
0.6 37.2 GO:0042734 presynaptic membrane(GO:0042734)
0.4 16.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 49.0 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.3 169.7 GO:0043025 neuronal cell body(GO:0043025)
0.3 46.4 GO:0030141 secretory granule(GO:0030141)
0.2 9.5 GO:0005801 cis-Golgi network(GO:0005801)
0.2 12.3 GO:0008021 synaptic vesicle(GO:0008021)
0.2 13.3 GO:0044297 cell body(GO:0044297)
0.1 47.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 179.4 GO:0005794 Golgi apparatus(GO:0005794)
0.1 19.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 142.7 GO:0005886 plasma membrane(GO:0005886)
0.1 148.0 GO:0016021 integral component of membrane(GO:0016021)
0.1 6.3 GO:0045202 synapse(GO:0045202)
0.1 3.7 GO:0005938 cell cortex(GO:0005938)
0.0 83.8 GO:0005634 nucleus(GO:0005634)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
26.7 133.4 GO:0033691 sialic acid binding(GO:0033691)
23.4 164.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
9.3 55.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
8.9 26.8 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
6.0 66.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
4.5 44.7 GO:0042301 phosphate ion binding(GO:0042301)
4.2 46.5 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
3.1 37.2 GO:0097109 neuroligin family protein binding(GO:0097109)
3.0 171.0 GO:0005179 hormone activity(GO:0005179)
2.9 85.4 GO:0001786 phosphatidylserine binding(GO:0001786)
2.9 67.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
2.5 54.1 GO:0017075 syntaxin-1 binding(GO:0017075)
1.8 66.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.8 19.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
1.8 47.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.5 28.8 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
1.4 56.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
1.2 8.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
1.2 61.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
1.2 75.4 GO:0042054 histone methyltransferase activity(GO:0042054)
1.1 52.7 GO:0045296 cadherin binding(GO:0045296)
0.9 5.4 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.9 26.4 GO:0005112 Notch binding(GO:0005112)
0.9 9.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.7 32.4 GO:0030507 spectrin binding(GO:0030507)
0.6 16.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 23.6 GO:0015485 cholesterol binding(GO:0015485)
0.5 56.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.5 37.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.4 10.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.4 47.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.4 7.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 14.0 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.2 19.6 GO:0000149 SNARE binding(GO:0000149)
0.2 89.7 GO:0005509 calcium ion binding(GO:0005509)
0.2 3.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 13.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.2 11.6 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.1 32.3 GO:0003729 mRNA binding(GO:0003729)
0.1 36.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 2.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 9.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 468.0 GO:0003674 molecular_function(GO:0003674)