Motif ID: Rfx2_Rfx7
Z-value: 1.770
Transcription factors associated with Rfx2_Rfx7:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Rfx2 | ENSMUSG00000024206.8 | Rfx2 |
| Rfx7 | ENSMUSG00000037674.9 | Rfx7 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Rfx7 | mm10_v2_chr9_+_72532609_72532828 | 0.28 | 2.9e-02 | Click! |
| Rfx2 | mm10_v2_chr17_-_56830916_56831008 | 0.19 | 1.6e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 139 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.4 | 31.9 | GO:0034441 | plasma lipoprotein particle oxidation(GO:0034441) |
| 0.2 | 18.1 | GO:0007631 | feeding behavior(GO:0007631) |
| 0.1 | 16.5 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 1.6 | 14.8 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.5 | 13.0 | GO:0035082 | axoneme assembly(GO:0035082) |
| 0.1 | 11.4 | GO:0051321 | meiotic cell cycle(GO:0051321) |
| 3.2 | 9.7 | GO:2000314 | negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
| 0.0 | 7.7 | GO:0007018 | microtubule-based movement(GO:0007018) |
| 1.5 | 7.6 | GO:2001170 | negative regulation of ATP biosynthetic process(GO:2001170) |
| 1.8 | 7.4 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.4 | 7.4 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.1 | 6.9 | GO:0034620 | cellular response to unfolded protein(GO:0034620) |
| 0.8 | 6.5 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.7 | 6.5 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
| 0.8 | 6.4 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 0.7 | 6.0 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.2 | 5.6 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.1 | 5.6 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.6 | 5.1 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.2 | 4.7 | GO:0007271 | synaptic transmission, cholinergic(GO:0007271) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 73 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 31.9 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 1.4 | 27.4 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.2 | 19.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.2 | 16.4 | GO:0031514 | motile cilium(GO:0031514) |
| 0.7 | 9.2 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.3 | 8.8 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 1.3 | 7.7 | GO:0036157 | axonemal dynein complex(GO:0005858) outer dynein arm(GO:0036157) |
| 0.3 | 7.6 | GO:0005605 | basal lamina(GO:0005605) |
| 2.5 | 7.5 | GO:0036156 | inner dynein arm(GO:0036156) |
| 1.5 | 6.0 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.1 | 5.2 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
| 0.0 | 4.9 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 4.5 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.5 | 4.4 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.2 | 4.2 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.4 | 4.0 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.2 | 3.6 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.9 | 3.5 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567) |
| 0.6 | 3.5 | GO:0016011 | dystroglycan complex(GO:0016011) |
| 0.3 | 3.4 | GO:0042612 | MHC class I protein complex(GO:0042612) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 99 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.5 | 31.9 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.1 | 19.2 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.9 | 18.0 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.2 | 10.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.2 | 10.7 | GO:0003774 | motor activity(GO:0003774) |
| 0.2 | 8.7 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.9 | 7.6 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 1.2 | 6.0 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 1.8 | 5.4 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
| 0.0 | 5.4 | GO:0022832 | voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832) |
| 0.6 | 4.7 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.1 | 4.7 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.0 | 4.2 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
| 0.2 | 4.0 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.7 | 3.5 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.1 | 3.5 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.2 | 3.4 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.2 | 3.4 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.1 | 3.4 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.3 | 3.1 | GO:0031996 | thioesterase binding(GO:0031996) |
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